N/A N=30 Effect of Local Anaesthetic Volume on Axillary Brachial Plexus Block Duration
Brachial Plexus Blockade
Primary: Overall Duration of Sensory Block. — 165; 188 minutes — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Effect of Local Anaesthetic Dilution on the Characteristics of Ultrasound Guided Axillary Brachial Plexus Block
Brachial Plexus Blockade
Primary: Onset of Axillary Block — 8.75; 6.25 minutes — p=0.03
N/A N=19 Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery
Basal Cell Carcinoma · Squamous Cell Carcinoma
Primary: The Number of Subjects With Detectable Serum Lidocaine Concentrations (<0.1 ug/mL) at Each Blood Draw. — 0; 1; 0; 2 Participants
Phase 4 N=25 Effectiveness Study of Different Local Anesthetic Mixtures
Pain
Primary: Length of Action — 6.63; 7.02; 7.48; 7.16 minutes — p=0.359
Phase 4 N=150 Local Anesthetics for Pain Reduction Prior to IV Line Placement
Pain · Local Anesthesia for Peripheral Intravenous Catheterization
Primary: Pain Score Following Anesthetic Administration — 2.81; 1.64; 2.05 units on a scale
N/A N=49 Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers.
Anesthesia
Primary: Participants Anesthetic Preference — 32; 16 participant preference selection
Phase 4 N=156 Preventing Propofol-associated Injection Pain
Pain
Primary: Verbal Pain Score — 3; 0; 0 Units on a scale — p=<0.0001
Phase 2 N=66 The Prevention of Hypotension After Epidural Analgesia After Major Surgery
Hypotension · Pain
Primary: Changes Between the 3 Groups Assessed by Blood Pressure Measurement — 5; 2; 3; 10 Participants — p=0.165
N/A N=91 Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics
Methemoglobinemia
Primary: Peak Methemoglobin Blood Levels — 3.55; 1.63; 1.60 percentage of methemoglobin in blood — p=<.001
Phase 3 N=233 Lidocaine + Clonidine for Intraoral Anesthesia in Patients With Diabetes Mellitus Type 2
Diabetes Mellitus · Local Anesthesia
Primary: Duration of Intraoral Local Anesthesia — 132.48; 173.27; 182.09; 195.35 minutes — p=<0.05
Phase 4 N=13 The Pharmacokinetics of 4% Lidocaine Gel When Applied Topically to the Breasts
Adverse Effects
Primary: Pharmacokinetic Parameters Based on Plasma Concentration of Lidocaine and MEGX in Nanograms/Milliliter. — NA; NA nanograms/mililiter — p=<0.05
N/A N=19 The Adverse Drug Reaction (ADRe) Profile for Polypharmacy
Polypharmacy
Primary: Number of Participants With Changes in Signs and Symptoms Related to Adverse Effects of Prescribed Medicines. Clinical Gains and Benefits to Residents — 17 Participants
Phase 4 N=60 Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar
Anesthetic Effectiveness
Primary: Successful Pulpal Anesthesia. — 37; 27; 22; 33 participants
N/A N=1,194 Drug Use Investigation Of Gabapentin
Epilepsies, Partial
Primary: Number of Participants With Treatment-Related Adverse Events Unexpected From Japanese Package Insert — 27 participants
N/A N=23 Clinical Outcomes of Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine
Anesthesia
Primary: Mean Time to Pulpal Response After Mandibular Molar Anesthesia — 99; 98 Minutes — p=0.74
N/A N=478 Lidocaine For Neuroprotection During Cardiac Surgery
Cognitive Decline
Primary: Change in Cognitive Function From Baseline Characterized as Continuous Cognitive Change — 0.07; 0.07 units on a scale
N/A N=24 Clinical Outcomes Maxilla: Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine
Anesthesia
Primary: Mean Time to Pulpal Response After Maxillary Molar Anesthesia — 98.8; 84.5 minutes
Phase 4 N=72 Safety of Gebauer's Pain Ease and Gebauer's Ethyl Chloride
Spray · Pain · Safety Issues
Primary: Presence of Microbial Growth (1+ CFU) — 2; 1; 1; 1 Number of samples with 1+ CFU — p=0.317
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
N/A N=100 Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena
Pharyngitis
Primary: Visual Analogue Scale(0-100mm) by the Subject. — 51; 40; 22; 9 mm
N/A N=24 Comparison Between Epinephrine and Clonidine as Adjuvants to Lidocaine in Axillary Brachial Plexus Block.
Brachial Plexus Blockade
Primary: Onset of Sensory Block — 10; 5 minutes — p=<0.001
Phase 4 N=20 Buffered Local Anesthetic
Dental Pain
Primary: Pain Score as Measured by the Behavior Pain Scale — 2.24; 2.61 score on a scale — p=0.005
N/A N=76 Local Anesthesia and Pain Perception During an Amniocentesis
Pregnancy
Primary: Intensity of Perceived Maternal Pain as Measured by the Visual Analogue Scale (VAS) — 9.5; 18.4 units on a scale
Phase 4 N=31 Anesthetic Effect Duration Assessment
Healthy Volunteers
Primary: Duration of Anesthesia(Minutes) — 80; 140; 0; 400 Minutes
Early Phase 1 N=90 Prevalence of Lidocaine Ineffectiveness in Adults With and Without ADHD
ADHD · PMS
Primary: Number of Subjects With Lidocaine Ineffectiveness — 11; 9; 16; 5 Participants — p=0.017
Phase 3 N=646 Topical Application of Cocaine HCl 4%, or 10%, or Placebo Solution in Local (Topical) Anesthesia
Any Ear Nose or Throat Conditions · With Identified Need for a Diagnostic Procedure or Surgery on or Through the Mucous Membranes of the Nasal Cavities
Primary: Immediate and Sustained Anesthetic Success for Cocaine HCl 4% Topical Solution and Placebo Topical Solution — 0.7093; 0.1969 proportion of participants — p=<0.0001
N/A N=88 Efficacy of Buffered Lidocaine in Patients With Facial Swelling
Orofacial Swelling
Primary: Pain Measurement as Assessed on a Heft-Parker 170 mm Visual Analog Scale — 69.3; 59.2 units on a scale
Phase 4 N=48 Effects of Intravenous Lidocaine Associated With Magnesium Sulfate on the Cisatracurium-Induced Neuromuscular Block
Neuromuscular Block
Primary: Latency — 139.70; 151.30; 147.80 seconds — p=0.9651
N/A N=394 Observational Study on 2-chloroprocaine Hydrochloride 1%
Neurological Complication, in Particular TNS or CES
Primary: Number of Participants With Adverse Events — 9; 5 participants
Phase 4 N=90 The Effects of Scalp Block With Bupivacaine Versus Levobupivacaine
Hypertension
Primary: Change in Mean Arterial Pressure — 110; 105; 100 mmHg