N/A N=49 Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers.
Anesthesia
Primary: Participants Anesthetic Preference — 32; 16 participant preference selection
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=25 Effectiveness Study of Different Local Anesthetic Mixtures
Pain
Primary: Length of Action — 6.63; 7.02; 7.48; 7.16 minutes — p=0.359
N/A N=30 Effect of Local Anaesthetic Volume on Axillary Brachial Plexus Block Duration
Brachial Plexus Blockade
Primary: Overall Duration of Sensory Block. — 165; 188 minutes — p=<0.001
Early Phase 1 N=70 Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Surgical Anesthesia, Cesarean Section
Primary: The Onset Time to Surgical Anesthesia — 558; 655 seconds — p=0.10
Phase 4 N=64 Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis
Anesthesia of Mucous Membrane
Primary: Measurement of Pain Associated With Injection, in Millimeters, According to Visual Analog Scale — 38.5; 26.9 mm
N/A N=100 Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena
Pharyngitis
Primary: Visual Analogue Scale(0-100mm) by the Subject. — 51; 40; 22; 9 mm
N/A N=154 Effect of Local Anesthetic Dose on Interscalene Block
Shoulder Arthroscopy · Interscalene Block
Primary: Handgrip Strength — 6.45; 2.98 kg
Phase 4 N=150 Local Anesthetics for Pain Reduction Prior to IV Line Placement
Pain · Local Anesthesia for Peripheral Intravenous Catheterization
Primary: Pain Score Following Anesthetic Administration — 2.81; 1.64; 2.05 units on a scale
Phase 4 N=60 Testing the Anesthetic Effectiveness of Three Different Dental Local Anesthetics Injected Next to a Lower First Molar
Anesthetic Effectiveness
Primary: Successful Pulpal Anesthesia. — 37; 27; 22; 33 participants
Phase 3 N=59 The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
Pain, Procedural
Primary: Post Operative Pain — 13; 10 Participants
N/A N=19 Serum Concentration of Lidocaine After Local Injection During Mohs Micrographic Surgery
Basal Cell Carcinoma · Squamous Cell Carcinoma
Primary: The Number of Subjects With Detectable Serum Lidocaine Concentrations (<0.1 ug/mL) at Each Blood Draw. — 0; 1; 0; 2 Participants
Phase 4 N=35 Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
Endodontic Disease · Post Operative Pain · Symptomatic Irreversible Pulpitis
Primary: Post-operative Pain Level 6 Hours on a Visual Analog Scale — 64.2; 43.1 units on a scale
Phase 4 N=43 Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
Adverse Reaction to Spinal Anesthetic · Maternal Care for Cervical Incompetence
Primary: Time to Resolution of Motor Block — 109; 112 minutes
Phase 4 N=31 Anesthetic Effect Duration Assessment
Healthy Volunteers
Primary: Duration of Anesthesia(Minutes) — 80; 140; 0; 400 Minutes
N/A N=76 Local Anesthesia and Pain Perception During an Amniocentesis
Pregnancy
Primary: Intensity of Perceived Maternal Pain as Measured by the Visual Analogue Scale (VAS) — 9.5; 18.4 units on a scale
Phase 2 N=40 Experimental Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray in Normal Volunteers
Anesthesia
Primary: Duration of Anesthesia as Measured by Pin Prick Test (PPT) for One Spray CTY-5339-A Compared to One Spray CTY-5339-CB — 17.9; 16.4 minutes — p=0.322
Phase 4 N=201 Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars
Irreversible Pulpitis
Primary: Anesthetic Success Rate of Supplemental Infiltration Injection — 22; 25; 23; 12 Participants — p=.901
Phase 4 N=150 Split Face Study of the Duration of Local Anesthetics
Anesthetics, Local
Primary: Time to Return to Baseline Sensation, as Determined by Binary Outcomes (Yes/no) in 15 Minute Increments — 54.34; 49.86; 43.13; 55.78 Minutes — p=0.93
Phase 4 N=72 Safety of Gebauer's Pain Ease and Gebauer's Ethyl Chloride
Spray · Pain · Safety Issues
Primary: Presence of Microbial Growth (1+ CFU) — 2; 1; 1; 1 Number of samples with 1+ CFU — p=0.317
Phase 2 N=33 Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures
Malignant Neoplasm
Primary: Total Dose of Propofol Administered to Each Patient — 2.94; 3.22 mg/kg — p=0.036
Phase 4 N=103 Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures
Eyelid Tumor · Eyelid Bump · Eyelid Deformity
Primary: Pain on Injection — 2.8; 3.6 score on a scale
Phase 4 N=24 Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic
Application Site Discomfort · Medical Device Discomfort
Primary: Time in Minutes That Tq Remained Inflated — 30.5; 22.4 Minutes
Phase 4 N=98 An Evaluation of the Effectiveness of Local Anesthetics Used During Intravenous Catheter Insertion
IV Insertion Pain
Primary: Differences in Patients' Perceptions of Pain Between Treatment Methods — 0.015; 0; 0; 1.909 units on a scale
Phase 4 N=100 The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections
Pain
Primary: Number of Participants Achieving Pulpal Anesthesia Success. — 44; 40 Participants — p=1.00
Phase 4 N=80 Testing the Anesthetic Effectiveness of Buffered Articaine Injected Next to a Lower First Molar.
Anesthetic Effectiveness
Primary: Number of Participants Achieving Pulpal Anesthesia. — 52; 57 Participants
Phase 2 N=120 Local Anesthetics on Postsurgical Analgesia Following Posterior Colporrhaphy
Postoperative Pain
Primary: Change in Vaginal Pain Scores Using the Defense and Veterans Pain Rating Scale (Visual Analog Scale) Between Bupivacaine Alone Versus Exparel® Following Posterior…
N/A N=91 Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics
Methemoglobinemia
Primary: Peak Methemoglobin Blood Levels — 3.55; 1.63; 1.60 percentage of methemoglobin in blood — p=<.001
Phase 4 N=156 Preventing Propofol-associated Injection Pain
Pain
Primary: Verbal Pain Score — 3; 0; 0 Units on a scale — p=<0.0001
Phase 4 N=40 Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis
Symptomatic Irreversible Pulpitis
Primary: VAS Scores as Measures of Profoundness of Pulpal Anesthesia — 3.1; 1.2 Score on a scale
N/A N=24 Clinical Outcomes Maxilla: Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine
Anesthesia
Primary: Mean Time to Pulpal Response After Maxillary Molar Anesthesia — 98.8; 84.5 minutes