N/A N=34 Youth Smoking Cessation: Therapy +/- "The Patch"
Smoking
Primary: Acceptance of Nicotine Replacement Therapy — 26 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=139 Cigarette Smoking Among Young Adults
Cigarette Smoking · Smoking Behaviors
Primary: Puff Topography — 1108; 1045.2; 1084.6 mL
N/A N=199 Perceptions of Cigarette Smoking in Young Adults
Smoking, Cigarette
Primary: Subjective Response to Smoking Cigarettes From the Cigarette Evaluation Scale — 4.68; 4.50 score on a scale — p=>.05
Phase 2 N=49 Impact of Nicotine Reduction on Adolescent Cigarette Use, Alternative Tobacco Use, and Harm From Tobacco
Nicotine Dependence, Cigarettes, Uncomplicated
Primary: Average Cigarettes Smoked Per Day — 4.3; 8.0 average cigarettes per day — p=.111
N/A N=105 Young Adult EC Use and Respiratory Outcomes
E Cig Use
Primary: Spirometry to Measure the Change From Baseline in Forced Vital Capacity (FVC) — 4.42; 3.54; 4.61; 3.68 liter
N/A N=362 Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents
Vaping
Primary: Change in Percentage of Participants Susceptible to Future Vaping — 1.1; -5.7; -2.3; -3.2 percentage of participants
N/A N=127 Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents
Attentional Bias · Smoking Cues · Positive Perceptions About Cigarette Smoking
Primary: Implicit Positive Smoking Expectancies, Measured by the Implicit Association Test — 1072.96; 1029.87 milliseconds
Early Phase 1 N=62 Responses to E-Cigarette Advertising
E-Cig Use
Primary: Attention to Specific ad Feature — -1.7062; -0.9676; -1.8238 Beats per minute
N/A N=88 Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth
E-cigarette Use
Primary: Plasma Nicotine Concentration — 0.78; 1.08; 0.89; 1.16 ng/ml
N/A N=71 Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping
E-cigarette Use · Vaping
Primary: Participant Recruitment and Retention — 37; 31 Participants
Phase 3 N=39 Behavioral Activation Intervention, Reward Processing, and Youth Smoking Cessation
Smoking
Primary: Number of Participants Smoking-Abstinent for 7 Days, 12 Weeks Post Quit Date — 7 Participants
N/A N=187 Effects Among Smokers Who Use and Do Not Use E-Cigarettes
Toxicant Exposure
Primary: Toxicant Exposure — 40; 97 pg/ml
Phase 4 N=312 Smoking Cessation Study In Healthy Adolescent Smokers
Smoking Cessation
Primary: 4-Week Continuous Abstinence Rate: Percentage of Participants Who Remained Abstinent From Week 9 Through Week 12 — 20.2; 27.2; 18.0 percentage of participants — p=0.6337
Phase 1 N=42 Effects of E-cigarette Flavors on Youth TCORS 2.0
Nicotine Use Disorder
Primary: Liking: Difference Score in Liking/Wanting of Each E-cigarette Condition — 1.268; -3.916 score on a scale — p=0.053
N/A N=480 Impact of E-Cigarette Prevention Messages on Adolescents
Vaping Behavior
Primary: Mean Susceptibility to Vaping Score — 1.91; 1.82 score on a scale
N/A N=58 Decision Support for Smoking Cessation in Young Adults With Severe Mental Illness
Mental Illness · Tobacco Smoking · Psychotic Disorders
Primary: Number of Participants Who Utilized Smoking Cessation Treatment — 2; 1 Participants — p=0.65
Phase 3 N=157 Varenicline for Adolescent Smoking Cessation
Nicotine Dependence
Primary: Number of Participants With Cotinine-confirmed 7-day Point Prevalence Abstinence at the End of Treatment — 4; 4 Participants
N/A N=296 Motivation and Skills for Detained Teen Smokers
Motivational Intervention · Nicotine Anonymous · Cognitive Behavior Therapy
Primary: Cigarette Use, Average # of Cigarettes Per Smoking Day. — 8.01; 8.87; 8.89; 7.55 days
N/A N=186 Responses to Regulated E-Cigarette Advertisements
Tobacco Use
Primary: Tobacco Use at 1 Month — 5; 5 Participants
N/A N=1,565 Impact of Vaping Prevention Advertisements
Vaping
Primary: Mean Susceptibility to Vaping Score — 2.16; 2.21; 2.36 score on a scale
N/A N=37 Cigarette Smoking Decision Study
Tobacco Smoking
Primary: Demand Intensity as Assessed by a Behavioral Economic Demand Curve — 4.709677419; 2.580645161 puff bouts
N/A N=484 Parent eReferral to Tobacco Quitline
Secondhand Smoke
Primary: Number of Parent Smokers Who Enrolled in Quitline — 209; 245; 24; 5 Participants
N/A N=1,215 Comparison of Text and Pictorial Waterpipe Tobacco Warnings Among Young Adults
Waterpipe Tobacco Smoking
Primary: Behavioral Intentions — 1.83; 1.72; 2.21 score on a scale
N/A N=29 Electronic Cigarette Use in Young Adult Men and Women
Cigarette Smoking · Tobacco Use
Primary: Contextual Factors Associated With Tobacco Use Episode Reported Via Ecological Momentary Assessment — 3; 22; 11; 12 tobacco use episodes — p=0.002
N/A N=31 Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking
Smoking
Primary: Breath Sample (Expired Carbon Monoxide) — 18.77; 31.07; 25.38; 30.49 parts per million — p=0.92
N/A N=61 A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Nicotine Dependence · Nicotine Addiction · Nicotine Use Disorder
Primary: Overall Treatment Satisfaction Rating — 3.8 units on a scale
N/A N=3,070 Young Adult Smoker's Treatment Demand
Smoking Cessation
Primary: Program Enrollment — .05 proportion of click-throughs who enroll
N/A N=1,132 Correcting Public Misperceptions About Very Low Nicotine Content Cigarettes
Tobacco Use, Cigarette Use
Primary: Very Low Nicotine Content (VLNC) Misperception — 3.12; 3.04; 3.04; 3.36 score on a scale
N/A N=108 Cognitive and Emotional Skills to Aid Smoking Prevention
Tobacco Smoking
Primary: Specific Aim 1: Percentage of Participants Who Attended 13 or More Interventions — 41.0; 50; 40.5 percentage of participants
Phase 4 N=261 Varenicline for Nicotine Vaping Cessation in Adolescents
Vaping · Nicotine Dependence
Primary: Continuous 4-week Nicotine Vaping Abstinence at End of Treatment (Weeks 9-12) — 45; 12; 5 Participants — p=<0.001