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Alpha-1 Antitrypsin Deficiency

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Alpha-1 Antitrypsin Deficiency

16 trials tracked for Alpha-1 Antitrypsin Deficiency: 3 in phase 3 or 4.

16Trials tracked
3Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 3 2 Phase 2 8 Phase 1 2 Other / NA 3
  1. Phase 4 Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor) Completed
  2. Phase 3 Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults Completed
  3. Phase 3 The Safety and Tolerability of Alpha-1 Modified Process (MP) In Subjects With Alpha-1-antitrypsin (AAT) Deficiency Completed
  4. Phase 2 Effect of Double Dose of Alpha 1-antitrypsin Augmentation Therapy on Lung Inflammation. Completed
  5. Phase 2 Phase II, Safety and Efficacy Study of Kamada-alpha-1-antitrypsin (AAT) for Inhalation" Completed
  6. Phase 2 Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT) Completed
Show 10 more trials
  1. Phase 2 Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency Completed
  2. Phase 2 Alpha-1-Antitrypsin (AAT) To Treat Emphysema In AAT-Deficient Patients (EXACTLE) Completed
  3. Phase 2 Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency Completed
  4. Phase 2 Safety Dose Finding Study of ADVM-043 Gene Therapy to Treat Alpha-1 Antitrypsin (A1AT) Deficiency Completed
  5. Phase 2 Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD) Completed
  6. Phase 1 Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin (AAT) Deficiency Completed
  7. Phase 1 Pharmacokinetic Study of ARALAST (Human Alpha1- PI) Completed
  8. N/A Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability Completed
  9. N/A Alpha-1 Carrier Genomics Study Completed
  10. N/A Long-Term Follow-up Study of ADVM-043 Completed

Showing the 16 most-cited and recently-updated of 16 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

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