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Gastroenterology
Meta-analysis
Refractory ascites significantly reduces social, mental, and physical functioning in patients with advanced chronic liver disease
Refractory ascites significantly lowers quality of life for liver patients
This systematic review and meta-analysis of 1040 patients with refractory ascites found significantly lower scores in social functioning (-1…
Living with fluid buildup from advanced liver disease causes significant drops in physical, mental, and social health for both patients and …
Oct 16, 2026
Gastroenterology
Meta-analysis
FIPS AUC 0.821 outperforms MELD scores for 90-day mortality prediction in TIPS for ascites
New score outperforms MELD for predicting death after TIPS for bleeding
This meta-analysis of 5,180 patients undergoing TIPS for ascites or gastroesophageal bleeding compared MELD-based scores and the FIPS index …
A new scoring system called FIPS may better predict 90-day death risk after TIPS for bleeding than older MELD scores.
Jun 1, 2026
Gastroenterology
Phase I
First-in-human study finds VS-01 generally well tolerated in decompensated cirrhosis with ascites
Early safety study of VS-01 infusion in 12 patients with advanced liver disease
This phase 1b, open-label, non-randomized study in 12 patients with decompensated cirrhosis, ascites, and covert hepatic encephalopathy foun…
A new liver treatment called VS-01 was safe for patients with advanced disease, causing mostly mild stomach issues in an early study of 12 p…
Apr 9, 2026