CKD-MBD care should shift from biochemical targets to phenotype-informed, outcome-oriented management
New approach to managing bone and vascular health in kidney disease
This narrative review argues that chronic kidney disease-mineral and bone disorder (CKD-MBD) management should move beyond biochemical targe…
Doctors are pushing for a new way to treat bone and blood vessel issues in patients with chronic kidney disease.
Traditional Chinese Medicine and modern multi-organ networks offer integrated perspectives on the kidney-bone axis
New research explores ancient and modern ways to treat bone disease
This systematic review explores the historical and modern conceptual frameworks of the kidney-bone axis in CKD-MBD. It identifies shared hol…
Researchers are looking at how ancient medicine and modern science can work together to treat bone issues caused by kidney disease.
CKD-MBD medication titration is associated with serum calcium, phosphorus, and parathyroid hormone levels
Doctors Titrate Kidney Medications Based on Specific Lab Results
This observational study of 23,549 patients on hemodialysis found that titration patterns for vitamin D sterols and calcimimetics were assoc…
New data shows that doctors adjust kidney medications based on specific lab markers like calcium and phosphorus levels for thousands of dial…
Systematic Review and Meta-Analysis Links α-Klotho to Frailty and Bone Health in Aging
Higher Alpha-Klotho Levels Mean Less Frailty And Better Bones
This systematic review and meta-analysis of 109 studies found that higher circulating α-Klotho levels were associated with lower odds of fra…
New research shows that higher Alpha-Klotho levels protect against frailty and bone loss, offering hope for better aging outcomes.
Systematic review links gut microbiota dysbiosis to CKD-MBD, RA, OA, and OP pathogenesis
Your gut holds the key to your bone health
This systematic review examines the role of gut microbiota dysbiosis in chronic kidney disease-mineral and bone disorder (CKD-MBD), rheumato…
Gut bacteria directly influence bone strength and kidney health, yet current treatments ignore the digestive system where the real problem s…
Questions about Chronic Kidney Disease-Mineral and Bone Disorder
Does gut health impact the progression of Chronic Kidney Disease-Mineral and Bone Disorder?
Gut health impacts the progression of CKD-MBD by influencing inflammation, bone metabolism, and the production of metabolites that affect both bone and vascular health.
Full answer →How does gut bacteria affect my Chronic Kidney Disease-Mineral and Bone Disorder?
Gut bacteria affect CKD-MBD by creating a "gut-kidney-bone axis" where an imbalance in bacteria leads to inflammation, the buildup of uremic toxins, and disrupted mineral metabolism.
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