Research across Cancer
Related studies from across the Cancer family.
Camrelizumab plus chemotherapy is cost-effective for first-line treatment of advanced squamous non-small-cell lung cancer
Immune Checkpoint Inhibitors Show Cost-Effectiveness for Lung Cancer Treatment
This network meta-analysis evaluates the cost-effectiveness of six immune checkpoint inhibitor-based first-line therapies combined with chem…
New analysis shows specific immune checkpoint inhibitor combinations may be more cost-effective than chemotherapy for advanced lung cancer p…
VRE Prevalence 18.4% in Hematologic Malignancy Patients, Pooled Meta-Analysis Finds
Vancomycin-resistant Enterococcus is common in patients with certain blood cancers
This meta-analysis of 120 studies estimates the pooled prevalence of vancomycin-resistant Enterococcus (VRE) in patients with hematological …
A large review of 120 studies shows that nearly 1 in 5 patients with leukemia or lymphoma carry a resistant strain of bacteria.
Evaluating Cytokine and Molecular Biomarkers for Diagnosing Primary Vitreoretinal Lymphoma
Biomarkers Show Promise in Detecting Vitreoretinal Lymphoma
A meta-analysis identifies the IL-10 to IL-6 ratio and MYD88 as high-performing biomarkers for distinguishing vitreoretinal lymphoma from in…
New research identifies specific biomarkers that may help doctors more accurately detect and diagnose a rare type of eye cancer.
Blinatumomab plus chemotherapy improves disease-free and overall survival in pediatric B-ALL
Trial shows blinatumomab improves survival for pediatric B-cell leukemia
This meta-analysis of randomized trials found that adding blinatumomab to chemotherapy improved disease-free survival (RR 0.63) and overall …
Adding blinatumomab to chemotherapy may improve survival rates for children with specific types of high-risk or relapsed B-cell leukemia.
Brexucabtagene autoleucel achieves 88% overall response rate in relapsed or refractory mantle cell lymphoma
Trial Shows Brexucabtagene Autoleucel Provides Durable Benefit for Blood Cancers
This meta-analysis of 31 cohorts evaluates brexucabtagene autoleucel for relapsed or refractory mantle cell lymphoma and B-cell acute lympho…
Brexucabtagene autoleucel shows high response rates and durable benefits for adults with specific types of relapsed or refractory blood canc…
Exercise interventions improve bone mineral density, cardiorespiratory endurance, and quality of life in children with acute leukemia
Exercise May Help Kids With Leukemia Feel and Move Better
This best evidence summary synthesizes 16 systematic reviews and 2 clinical practice guidelines regarding exercise interventions for childre…
Exercise may improve bone strength, fitness, and quality of life in children with acute leukemia, a new evidence summary suggests.
Multiparametric MRI and image-guided neurointerventions provide critical roles in brain tumor management and surveillance
Advanced Imaging and Interventions Improve Brain Tumor Management
This narrative review examines the roles of advanced diagnostic imaging and image-generated neurointerventions in managing brain tumors, inc…
Newer imaging techniques and minimally invasive procedures are expanding how doctors detect, plan, and treat various types of brain tumors.
EBV prevalence varies widely across lymphoma subtypes, highest in ENKTL at 92.4%
EBV Presence Linked to Lymphoma Cases in People with HIV
This meta-analysis of 307 studies and over 21,140 lymphoma cases quantifies Epstein-Barr virus (EBV) prevalence across lymphoma subtypes, st…
A large review of over 21,000 cases shows that the Epstein-Barr virus is more common in certain lymphoma types among people living with HIV.
Deep learning for leukemia diagnosis faces fragmented research and limited multimodal integration in current literature
AI for leukemia diagnosis still fragmented, review finds
This scoping review evaluates deep learning techniques for leukemia detection across morphological, immunophenotyping, and molecular modalit…
A new review shows AI tools for leukemia diagnosis are promising but fragmented, with few using multiple data types.
CircRNAs act as signaling hubs for immune checkpoints and indicators of ICI response in lymphoma
CircRNAs May Help Predict Response to Lymphoma Immunotherapy
This systematic review examines the role of circRNAs, including EBV-encoded types, in immune evasion within lymphomas. The authors conclude …
New research suggests that specific molecules called circRNAs could help doctors predict how patients with lymphoma will respond to immune c…
Immunotherapy regimens for TKI-resistant NSCLC are not cost-effective without significant price reductions
New lung cancer treatments show better results but higher costs
This network meta-analysis evaluated the cost-effectiveness of three immunotherapy-based combinations compared to chemotherapy in patients w…
Newer drug combinations offer better survival for certain lung cancer patients, but high costs currently make them difficult to fund widely.
Mosunetuzumab plus polatuzumab vedotin achieved a 100% overall response rate in Japanese patients with LBCL
Trial shows promising results for relapsed large B-cell lymphoma
This Phase III randomized controlled trial analyzed a subgroup of 16 Japanese patients with relapsed or refractory large B-cell lymphoma. Th…
A new treatment combination showed a high response rate and longer progression-free survival for patients with a specific type of lymphoma.