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Chronic rhinosinusitis with nasal polyps

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Chronic rhinosinusitis with nasal polyps

6 trials tracked for Chronic rhinosinusitis with nasal polyps: 5 in phase 3 or 4 and 4 with published results. The most-cited published study has 138 citations.

6Trials tracked
5Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 3 Phase 3 2 Phase 1 1
  1. Phase 3 Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis Completed · 138 cited
  2. Phase 4 EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients Completed · 27 cited
  3. Phase 4 Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab) Completed · 2 cited
  4. Phase 4 Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52) Completed
  5. Phase 3 Dupilumab in Chinese Adult Participants With CRSwNP Completed
  6. Phase 1 Study Of PF-06817024 In Healthy Subjects, In Patients With Chronic Rhinosinusitis With Nasal Polyps And in Patients With Atopic Dermatitis Completed

Showing the 6 most-cited and recently-updated of 6 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Questions about Chronic rhinosinusitis with nasal polyps

Can mepolizumab help patients with asthma who also have nasal polyps?

Yes, mepolizumab can help patients with asthma who also have nasal polyps by reducing polyp size, improving symptoms, and lowering exacerbation risk.

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How long does tezepelumab treatment need to be for smell improvement?

Smell improvement from tezepelumab begins within days and continues to grow over 52 weeks of treatment.

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Will biologics help my quality of life if I have severe nasal polyps?

Yes, biologics significantly improve quality of life in severe nasal polyps by reducing symptoms, need for steroids, and surgery, with benefits seen in smell, congestion, and overall well-being.

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Do anti-IL-5 drugs work for chronic rhinosinusitis with nasal polyps?

Anti-IL-5 drugs like mepolizumab and tezepelumab improve symptoms and smell in chronic rhinosinusitis with nasal polyps, though surgery often adds extra benefit.

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Can tezepelumab help improve my sense of smell and taste over time?

Yes, tezepelumab significantly improves sense of smell and taste in adults with chronic rhinosinusitis with nasal polyps, with benefits seen as early as one week and sustained over 52 weeks.

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See all 5 questions about Chronic rhinosinusitis with nasal polyps →