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Home › Conditions › Chronic Total Occlusion

Chronic Total Occlusion

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Chronic Total Occlusion

2 trials tracked for Chronic Total Occlusion: 1 in phase 3 or 4.

2Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Other / NA 1
  1. Phase 4 Boston Scientific OffRoad™ Re-entry Catheter System for Subintimal Recanalization of Chronic Total Occlusions in Femoropopliteal Arteries Completed
  2. N/A Chronic Total Occlusion Percutaneous Coronary Intervention Study Completed

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Higher SII and FAR levels associated with poorly-developed coronary collateral circulation in CTO patients
Cardiology Cohort
Higher SII and FAR levels associated with poorly-developed coronary collateral circulation in CTO patients Higher Inflammation Markers Linked to Poorer Blood Flow Around Blocked Heart Arteries
This retrospective cohort analysis of 469 patients with coronary chronic total occlusion undergoing elective angiography evaluated systemic…
Higher inflammation markers predict poor natural blood flow around blocked heart arteries, helping doctors spot patients needing extra care.
Frontiers Apr 9, 2026
CTO PCI does not affect diastolic coupling in STEMI patients; elevated baseline LACI predicts mortality
Cardiology RCT
CTO PCI does not affect diastolic coupling in STEMI patients; elevated baseline LACI predicts mortality Does opening a blocked artery after a heart attack help the heart relax?
In this RCT of 200 STEMI patients with concurrent CTO, CTO PCI did not significantly affect left atrioventricular coupling index (LACI) at 4…
Opening a blocked artery after a heart attack doesn't help the heart relax, but early heart relaxation scores predict who is most at risk of…
Apr 3, 2026