Research across Cancer
Related studies from across the Cancer family.
TSH suppression therapy promotes tumor progression via G-protein signaling pathways in differentiated thyroid cancer
TSH Suppression Therapy Framework for Differentiated Thyroid Cancer
This systematic review synthesizes the biological mechanisms of TSH-mediated tumor progression and proposes a clinical decision-making frame…
New research outlines how TSH levels impact thyroid cancer growth and offers a new decision-making framework for personalized patient care.
I-SPECT/CT shows high patient-level specificity of 0.95 for detecting residual disease in DTC
Imaging technology shows promise for detecting thyroid cancer recurrence
This meta-analysis evaluates the diagnostic efficacy of I-SPECT/CT for identifying residual or recurrent disease in patients with differenti…
A new imaging method called I-SPECT/CT helps doctors find leftover or returning thyroid cancer cells with high accuracy after treatment.
Hemithyroidectomy is associated with a 3% higher risk difference in cancer recurrence rate
Hemithyroidectomy linked to higher thyroid cancer recurrence
This meta-analysis of 98,604 patients with differentiated thyroid carcinoma found that hemithyroidectomy (HT) was associated with a 3% highe…
A large meta-analysis found that hemithyroidectomy for differentiated thyroid cancer has a higher recurrence rate than total thyroidectomy, …
WBRT shows no significant survival benefit in thyroid cancer brain metastases meta-analysis
Whole-brain radiation shows no clear survival benefit for thyroid cancer brain metastases
A systematic review and individual patient data meta-analysis of 247 patients with thyroid cancer brain metastases found whole-brain radiati…
Whole-brain radiation therapy showed no clear survival benefit for patients with thyroid cancer that spread to their brain.
Nivolumab monotherapy yielded 12-month progression-free survival in metastatic anaplastic thyroid cancer
Off-label immunotherapy may help some patients with metastatic anaplastic thyroid cancer
This case report describes a 76-year-old female with metastatic anaplastic thyroid cancer treated with off-label nivolumab monotherapy. The …
A single case report suggests off-label nivolumab helped a 76-year-old woman live longer with metastatic anaplastic thyroid cancer.
Meta-analysis finds germline LTS and somatic TERT variants are mutually exclusive in thyroid cancer and melanoma
Two different cancer drivers do not appear together in these tumors
This meta-analysis of retrospective observational cohorts examined germline long-telomere syndrome variants and somatic TERT promoter altera…
A large review of nearly 2,000 adults with thyroid cancer or melanoma found that two specific genetic changes never occur in the same tumor.
Review of case report suggests multimodal therapy potential for unresectable intraductal papillary mucinous neoplasms of the bile duct
At-a-Glance
This review of a case report describes two patients with unresectable intraductal papillary mucinous neoplasms of the bile duct treated with…
A new three-drug combination shrank a rare bile duct tumor in one patient and stopped another from growing, offering hope for a cancer with …
Symptom Network Changes in Differentiated Thyroid Cancer Patients Undergoing Radioactive Iodine Therapy
Radioactive iodine therapy changes how symptoms connect in patients
This prospective cohort study of 520 patients with differentiated thyroid cancer found that radioactive iodine therapy significantly reorgan…
New research shows that radioactive iodine therapy reshapes how physical and psychological symptoms interact in people with thyroid cancer.
Central lymph node ratio threshold predicts lateral lymph node metastasis in pediatric differentiated thyroid carcinoma
One Number Might Predict Thyroid Cancer Spread in Children
This retrospective cohort study evaluated pediatric patients with differentiated thyroid carcinoma aged ≤14 years.
A simple number helps doctors predict if thyroid cancer will spread to side neck nodes in children under 14 years old.
TIRADS and Bethesda systems predict thyroid malignancy in 70 patients at Baghdad Teaching Hospital
Family history and neck swelling signal higher risk of thyroid cancer
This prospective cross-sectional study evaluated 70 patients with thyroid complaints at Baghdad Teaching Hospital.
A new look at thyroid nodules shows that family history and neck swelling are key signs of cancer, helping doctors catch it sooner.
Case series describes four clear cell variant papillary thyroid carcinoma cases with NCOA4-RET fusions
Rare Thyroid Cancer Has Unique Genetic Signature
This case series with literature review describes four pathologically confirmed cases of clear cell variant of papillary thyroid carcinoma d…
A rare thyroid cancer type may have a specific genetic cause that doctors can now look for.
Savolitinib and durvalumab combination yields response rates of 34% to 53% in papillary renal cancer patients
New Hope for a Tough Kidney Cancer Type
This single-arm phase II study evaluated savolitinib and durvalumab in 41 treatment-naïve or pretreated patients with papillary renal cancer…
A new drug pair breaks the shield blocking treatment for a rare kidney cancer type, offering patients a chance at longer survival after stan…