Research across Cancer
Related studies from across the Cancer family.
WBRT shows no significant survival benefit in thyroid cancer brain metastases meta-analysis
Whole-brain radiation shows no clear survival benefit for thyroid cancer brain metastases
A systematic review and individual patient data meta-analysis of 247 patients with thyroid cancer brain metastases found whole-brain radiati…
Whole-brain radiation therapy showed no clear survival benefit for patients with thyroid cancer that spread to their brain.
Nivolumab monotherapy yielded 12-month progression-free survival in metastatic anaplastic thyroid cancer
Off-label immunotherapy may help some patients with metastatic anaplastic thyroid cancer
This case report describes a 76-year-old female with metastatic anaplastic thyroid cancer treated with off-label nivolumab monotherapy. The …
A single case report suggests off-label nivolumab helped a 76-year-old woman live longer with metastatic anaplastic thyroid cancer.
Meta-analysis finds germline LTS and somatic TERT variants are mutually exclusive in thyroid cancer and melanoma
Two different cancer drivers do not appear together in these tumors
This meta-analysis of retrospective observational cohorts examined germline long-telomere syndrome variants and somatic TERT promoter altera…
A large review of nearly 2,000 adults with thyroid cancer or melanoma found that two specific genetic changes never occur in the same tumor.
Case report details multimodal treatment for aggressive thyroid carcinoma
First new treatment combination in six months stabilizes advanced thyroid cancer
A 61-year-old man with papillary thyroid carcinoma achieved disease stabilization after thyroidectomy, radiotherapy, and targeted therapy. T…
A 61-year-old man with advanced thyroid cancer saw his disease stop growing after a specific mix of treatments within six months of his diag…
Review of a case report on epithelioid clear cell mesothelioma in a 76-year-old male with 24 months follow-up
A 76-year-old man with rare cancer stayed cancer-free for two years
This publication is a review of a single case report involving a 76-year-old male with epithelioid clear cell mesothelioma. The patient had …
A 76-year-old man with a rare form of cancer had no signs of the disease returning after two years, offering hope for others facing this dif…
Review of case report suggests multimodal therapy potential for unresectable intraductal papillary mucinous neoplasms of the bile duct
At-a-Glance
This review of a case report describes two patients with unresectable intraductal papillary mucinous neoplasms of the bile duct treated with…
A new three-drug combination shrank a rare bile duct tumor in one patient and stopped another from growing, offering hope for a cancer with …
Symptom Network Changes in Differentiated Thyroid Cancer Patients Undergoing Radioactive Iodine Therapy
Radioactive iodine therapy changes how symptoms connect in patients
This prospective cohort study of 520 patients with differentiated thyroid cancer found that radioactive iodine therapy significantly reorgan…
New research shows that radioactive iodine therapy reshapes how physical and psychological symptoms interact in people with thyroid cancer.
Central lymph node ratio threshold predicts lateral lymph node metastasis in pediatric differentiated thyroid carcinoma
One Number Might Predict Thyroid Cancer Spread in Children
This retrospective cohort study evaluated pediatric patients with differentiated thyroid carcinoma aged ≤14 years.
A simple number helps doctors predict if thyroid cancer will spread to side neck nodes in children under 14 years old.
TIRADS and Bethesda systems predict thyroid malignancy in 70 patients at Baghdad Teaching Hospital
Family history and neck swelling signal higher risk of thyroid cancer
This prospective cross-sectional study evaluated 70 patients with thyroid complaints at Baghdad Teaching Hospital.
A new look at thyroid nodules shows that family history and neck swelling are key signs of cancer, helping doctors catch it sooner.
Separate molecular profiling of mixed endometrial carcinoma components yields limited prognostic data in a small retrospective cohort
Separate tumor profiling may reveal hidden risks in mixed endometrial cancer
This hypothesis-generating retrospective cohort analysis included 8 patients with mixed endometrial carcinomas (MEEC).
In mixed endometrial cancer, testing each tumor component separately could uncover risk profiles that standard testing misses.
Savolitinib and durvalumab combination yields response rates of 34% to 53% in papillary renal cancer patients
New Hope for a Tough Kidney Cancer Type
This single-arm phase II study evaluated savolitinib and durvalumab in 41 treatment-naïve or pretreated patients with papillary renal cancer…
A new drug pair breaks the shield blocking treatment for a rare kidney cancer type, offering patients a chance at longer survival after stan…
Machine learning models predict survival in lymph-node-positive medullary thyroid carcinoma
A Machine Learning Tool Now Predicts Survival for One Tricky Thyroid Cancer
This cohort study evaluated machine learning models for predicting survival in patients with lymph-node-positive medullary thyroid carcinoma…
A new AI tool predicts survival for aggressive medullary thyroid cancer that has spread to lymph nodes, revealing that skipping surgery is t…