CHIP mutations linked to higher lymph node metabolic activity in people with treated HIV
CHIP Mutations Linked to Lymph Nodes Not Arteries in HIV Patients
This cohort study of 230 people with HIV ages 31-74 years found that clonal hematopoiesis of indeterminate potential (CHIP) was not associat…
New research shows HIV patients with specific gene changes have active lymph nodes but not thicker arteries yet.
Specific TET2 and DNMT3A mutations drive most CHIP clinical risk in large biobank analysis
Specific blood cell mutations linked to higher disease risk in large biobank study
An observational study of over 1 million individuals across three biobanks found that a discrete subset of enzymatically disruptive mutation…
Certain blood cell mutations linked to heart disease and blood cancers are worse than others, and a new blood test can now measure this spec…
Phase 2a trial of DFV890 and MAS825 for inflammation in CHD/CHIP patients completes with 31 participants
Can two experimental drugs calm the dangerous inflammation linked to heart disease and a blood condition called CHIP?
A Phase 2a, multi-center, randomized, placebo-controlled, blinded study evaluated the efficacy, safety, and tolerability of DFV890 (oral dai…
A new trial tested two experimental drugs to safely turn down the dangerous inflammation driving heart disease in patients with CHIP.