CAR T-cell therapies targeting specific antigens show potential for treating pediatric CNS tumors
New CAR T-cell therapies show promise for pediatric brain tumors
This narrative review synthesizes 18 studies, including preclinical and early-phase clinical trials, regarding CAR T-cell therapy for pediat…
CAR T-cell therapy is showing potential to shrink tumors and extend life in children with aggressive brain cancers like DIPG.
TRAM MRI shows 0.89 AUC for differentiating treatment response from radionecrosis in CNS tumors
New MRI mapping helps tell tumor growth from radiation damage
This diagnostic meta-analysis of 286 patients with CNS tumors treated with radiotherapy found that treatment response assessment maps (TRAMs…
Doctors can now better distinguish between shrinking tumors and tissue damage caused by radiation using a specific MRI mapping tool.
EMILIN-1 shows dual tumor-suppressive and promoting roles in brain tumor biology review
Review explores dual role of EMILIN-1 protein in brain tumor biology
A systematic review of experimental data describes EMILIN-1's complex role in nervous system tumors.
A protein called EMILIN-1 might slow brain tumors in some ways but could also change the immune response to help them grow faster.