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Coronavirus infection

Part of Middle East Respiratory Syndrome

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for coronavirus infection

16 trials tracked for coronavirus infection: 3 in phase 3 or 4 and 2 with published results. The most-cited published study has 55 citations.

16Trials tracked
3Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 1 Phase 3 2 Phase 2 9 Other / NA 4
  1. Phase 3 Novel Experimental COVID-19 Therapies Affecting Host Response Completed · 55 cited
  2. Phase 4 BCG Vaccine for Health Care Workers as Defense Against COVID 19 Completed · 7 cited
  3. Phase 3 Convalescent Plasma Collection and Treatment in Pediatrics and Adults Completed
  4. Phase 2 Convalescent Plasma for Patients With COVID-19 Completed
  5. Phase 2 Evaluation of Activity and Safety of Oral Selinexor in Participants With Severe COVID-19 Infection Completed
  6. Phase 2 Pilot Study of Ensifentrine or Placebo Delivered Via pMDI in Hospitalized Patients With COVID-19 Completed
Show 10 more trials
  1. Phase 2 COVFIS-HOME: COVID-19 Pilot Study of Fisetin to Alleviate Dysfunction and Decrease Complications Completed
  2. Phase 2 A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 Completed
  3. Phase 2 Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) Completed
  4. Phase 2 Sars-CoV-2/COVID-19 Ivermectin Navarra-ISGlobal Trial Completed
  5. Phase 2 CONTAIN COVID-19: Convalescent Plasma to Limit COVID-19 Complications in Hospitalized Patients Completed
  6. Phase 2 University of Utah COVID-19 Hydrochloroquine Trial Completed
  7. N/A Efficacy of Oral Rinses for Inactivation of COVID-19 (MOR2) Completed
  8. N/A Effect of Respiratory Exerciser on Pulmonary Functions of COVID-19 Patients Completed
  9. N/A Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19) Completed
  10. N/A Community Collaboration to Combat COVID-19 (C-FORWARD) Completed

Showing the 16 most-cited and recently-updated of 16 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Coronavirus infection: what the trials found

Convalescent plasma has been evaluated in multiple trials for the treatment of coronavirus infection. One Phase 3 trial included convalescent plasma as an intervention 1. In a Phase 2 study, convalescent plasma was associated with a reduction in ventilator days (15.6 vs. 4.2) and a higher rate of normal chest X-rays at 28 days (9 vs. 3) 8. Another Phase 2 trial evaluating convalescent plasma showed no significant difference in clinical improvement scores on the WHO 11-point Ordinal Scale at either 14 or 28 days 9.

The BCG vaccine was evaluated in a Phase 4 study for coronavirus infection 2.

Recent results — preliminary, needs further review

  • A study of throat/nose swabs showed increasing percentages of patients with positive detection of IgG specific antibodies to the SARS-CoV-2 spike-protein over time (34.9% to 61.9%) and nucleocapsid protein (14.7% to 14.3%) 13.

For the clinician treating this condition

  • Convalescent plasma shows mixed results in clinical outcomes; while one study reported a significant reduction in ventilator days, another showed no difference in WHO clinical improvement scores.
  • The BCG vaccine has been evaluated in Phase 4 trials for this condition.

AI synthesis of 5 cited trials, updated Jun 29, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.