Vitamin D supplementation shows low certainty reductions in urinary markers for diabetic kidney disease
Vitamin D shows limited benefit for diabetic kidney disease
This umbrella review meta-analysis evaluates vitamin D and its analogs in patients with diabetic kidney disease. While some reduction in uri…
Vitamin D may lower protein in urine for diabetic kidney disease, but evidence is weak and no benefit for kidney function or survival.
miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
Specific MicroRNA Signatures Linked to Type 1 Diabetes Complications
This systematic review and meta-analysis of 9 studies involving 34 contrasts identified specific circulating miRNA signatures associated wit…
Researchers identified specific microRNA signals that may help track kidney and eye damage in patients with Type 1 Diabetes.
Narrative review of salvianolic acids for kidney disease pharmacokinetics and anti-fibrotic activity
Salvianolic Acids Show Potential for Kidney Disease Treatment
This narrative review synthesizes evidence on salvianolic acids A, B, and C for kidney conditions. It focuses on pharmacokinetic parameters,…
A review suggests salvianolic acids may help kidney conditions, though low absorption and fast metabolism limit current use.
Cross-sectional study links declining nephron number to CKD stage in diabetic nephropathy
Kidney Filters Fail One by One in Diabetes
This cross-sectional observational study abstract examined 105 patients with biopsy-proven diabetic nephropathy and overt proteinuria, strat…
Even when kidneys look okay, their filters are quietly failing in people with diabetes, a new study shows — and that could explain why damag…
Meta-analysis of observational studies associates serum lipid levels with diabetic nephropathy risk
High Triglycerides Raise Risk of Kidney Damage in Diabetes
This meta-analysis synthesizes data from 15 observational studies examining serum lipid levels and diabetic nephropathy risk.
Managing blood fats might help protect your kidneys if you have diabetes.
Meta-analysis of salidroside in diabetic nephropathy animal models shows mixed renal outcomes with high heterogeneity
Salidroside May Help Protect Kidneys in Diabetes
This systematic review and meta-analysis evaluated salidroside monotherapy in 257 diabetic nephropathy animal models.
A natural compound from Rhodiola may protect kidneys in diabetes by calming inflammation and fighting oxidative stress.
Liuwei Dihuang Pills combined with conventional medicine reduces albuminuria in early diabetic nephropathy
An Ancient Herbal Formula May Protect Kidneys From Diabetes Damage
A meta-analysis of 7 RCTs with 1,007 patients with early diabetic nephropathy found that adding Liuwei Dihuang Pills to conventional Western…
Adding an ancient Chinese herbal formula to standard diabetes care significantly reduced early kidney damage markers in patients with type 2…
Higher UACR associates with Gram-negative dominance and worse inflammation in diabetic foot infections
A Simple Urine Test Could Predict Your Diabetic Foot Infection
This retrospective cross-sectional observational study evaluated 325 diabetic foot infection patients from a northern Chinese tertiary hospi…
A common check for kidney health may also act as a crystal ball for foot infections, helping doctors pick the winning antibiotic from the st…
Chinese CKD Stage 5 HD patients report ~13 symptoms; symptom distress negatively correlates with QoL
What's the biggest struggle for people on dialysis? It's not just physical symptoms — it's worry and sleepless nights
A multi-center cross-sectional study of Chinese CKD Stage 5 patients on hemodialysis found patients reported an average of 13 symptoms, with…
People on dialysis in China face severe worry, sexual problems, and sleepless nights, with more symptoms directly lowering their quality of …
Research across Diabetes
Related studies from across the Diabetes family.
AI-OCT reports reduced false-positive DME referral rates from 69.1% to 24.1%
AI technology reduces unnecessary referrals for diabetic macular edema
This randomized clinical trial evaluated the impact of AI-OCT reports on identifying diabetic macular edema (DME) in patients with diabetes.…
New research shows that adding AI-powered imaging can significantly cut down on false alarms when screening patients for eye issues caused b…
Balanced crystalloids reduce time to DKA resolution by 1.60 hours compared to 0.9% saline
Balanced Crystalloids May Speed Recovery in Pediatric Diabetic Ketoacidosis
This meta-analysis of 320 pediatric patients with diabetic ketoacidosis found that balanced crystalloids significantly reduced the time to D…
A review of data suggests balanced crystalloid fluids may resolve diabetic ketoacidosis faster than standard saline in children.
Early subcutaneous basal insulin plus IV insulin reduces time to DKA resolution by 4.06 hours
Early Subcutaneous Insulin Shortens Recovery Time for Diabetic Ketoacidosis
This meta-analysis of randomized controlled trials evaluated adding early subcutaneous basal insulin to intravenous insulin for adults with …
Adding early subcutaneous insulin to IV treatment can speed up recovery for patients with diabetic ketoacidosis without increasing safety ri…
Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
Fluocinolone Acetonide Implant May Reduce Injection Frequency for DME
A Phase 4 trial shows fluocinolone acetonide implants achieve similar visual outcomes to aflibercept with significantly fewer total injectio…
A new eye implant for diabetic macular edema may significantly reduce the number of monthly injections needed to maintain vision.
High prevalence of microvascular and macrovascular complications among adult Ugandans with diabetes
High rates of diabetes complications found in adult Ugandans
This meta-analysis examined the prevalence of various diabetic complications, including neuropathy and retinopathy, in a large cohort of adu…
More than half of Ugandan adults with diabetes suffer from nerve damage, highlighting a critical need for earlier screening and better care.
Immunometabolic dysregulation drives hyperalgesia and hypoesthesia in diabetic peripheral neuropathy
New research explores how inflammation drives nerve damage in diabetes
This narrative review explores the pathophysiology of diabetic peripheral neuropathy, focusing on how hyperglycemia, lipotoxicity, and intes…
Chronic high blood sugar causes more than just high glucose; it triggers a cycle of inflammation and immune stress that damages nerves.
Chronic hyperglycemia causes multi-level nerve damage across the peripheral, autonomic, and central nervous systems
Understanding how high blood sugar damages the entire nervous system in diabetes
This narrative review synthesizes how chronic hyperglycemia impacts the entire neuroaxis in patients with diabetes. It details metabolic and…
High blood sugar can damage nerves throughout the whole body. This affects your senses, movement, and internal organs.
Intravitreal ziv-aflibercept reduces central macular thickness and improves visual acuity in DME and RVO
Trial shows ziv-aflibercept improves vision in macular edema cases
This systematic review and meta-analysis of 5 RCTs and 8 observational studies found that intravitreal ziv-aflibercept significantly reduced…
A new eye treatment called ziv-aflibercept may help reduce swelling and improve vision for patients with specific types of macular edema.
Local antibiotic delivery systems increase healing rates in diabetic foot osteomyelitis compared with control groups in this meta-analysis
Local Antibiotics May Boost Healing in Diabetic Foot Infections
This systematic review and meta-analysis evaluated local antibiotic delivery systems versus control groups for patients with diabetic foot o…
A new analysis suggests local antibiotic delivery may improve healing for diabetic foot bone infections, but more research is needed.
Antibiotic cement achieves 85.2% healing rate in diabetic foot osteomyelitis meta-analysis
Antibiotic cement may help heal diabetic foot infections without major surgery
A systematic review and meta-analysis of 82 patients with diabetic foot osteomyelitis found a weighted healing rate of 85.2% with antibiotic…
A meta-analysis suggests antibiotic-impregnated cement can heal diabetic foot osteomyelitis in most patients, though some still need surgery…
SGLT2 inhibitor use associated with increased diabetic ketoacidosis risk, especially with elevated HbA1c
New review shows SGLT2 drugs raise DKA risk when blood sugar is high
This meta-analysis of observational and randomized trials found SGLT2 inhibitor use is associated with an increased risk of diabetic ketoaci…
A big review of many studies found that medicines for diabetes called SGLT2 inhibitors can increase the chance of a serious condition called…
Perioperative anti-VEGF injections improve vision and reduce bleeding in proliferative diabetic retinopathy
Anti-VEGF injections before eye surgery improve vision and reduce bleeding in diabetic retinopathy
This network meta-analysis evaluated the timing of perioperative anti-VEGF injections for proliferative diabetic retinopathy. Results indica…
A network meta-analysis of 2,646 eyes found that perioperative anti-VEGF injections improved vision and reduced bleeding in patients with pr…