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Difficult-to-Control Asthma

Part of Asthma

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Asthma

Related studies from across the Asthma family.

Depemokimab maintains trough concentrations 90% above EC level with predicted half-life of 47 days
Allergy & Immunology RCT
Depemokimab maintains trough concentrations 90% above EC level with predicted half-life of 47 days New data supports twice yearly dosing for asthma and sinus disease
This observational analysis of pharmacokinetic and pharmacodynamic data from Phase I and Phase III trials evaluated depemokimab in patients …
A new analysis of trial data shows a specific treatment for asthma and nasal polyps may only need to be given twice a year.
High-dose omega-3 PUFA and EPA significantly reduce risk of asthma and wheezing in children
Allergy & Immunology Meta-analysis
High-dose omega-3 PUFA and EPA significantly reduce risk of asthma and wheezing in children High dose omega-3 fatty acids may lower asthma risk in children
This meta-analysis of 4156 children evaluated the impact of omega-3 polyunsaturated fatty acids on asthma. Findings indicate that high-dose …
New data suggests that specific high doses of omega-3 fatty acids and EPA could significantly reduce the risk of asthma and wheezing in chil…
Cloud-based intelligent management system improves medication adherence 89.2% vs 58.0% in pediatric asthma
Allergy & Immunology RCT
Cloud-based intelligent management system improves medication adherence 89.2% vs 58.0% in pediatric asthma Smart monitoring helps children with asthma manage their symptoms better
This randomized controlled trial of 208 children aged 6 to 12 years found that a cloud-based integrated intelligent management system signif…
A cloud-based management system significantly improved medication habits and lung function for children living with bronchial asthma.
Asthma and COPD are associated with significantly increased risk of pertussis infection
Allergy & Immunology Meta-analysis
Asthma and COPD are associated with significantly increased risk of pertussis infection Asthma and COPD Patients Face Higher Risk of Pertussis Infection
This meta-analysis of 10 studies involving over 18.6 million participants indicates that patients with asthma or COPD face a higher risk of …
People with asthma or COPD may face a significantly higher risk of contracting pertussis, according to an analysis of over 18 million partic…
Maternal hypertensive disorders of pregnancy are associated with increased offspring asthma risk
Psychiatry Meta-analysis
Maternal hypertensive disorders of pregnancy are associated with increased offspring asthma risk Maternal Pregnancy High Blood Pressure Linked to Higher Asthma Risk
This meta-analysis of over three million mother-infant pairs found a significant association between maternal hypertensive disorders of preg…
New data suggests that mothers with high blood pressure during pregnancy may have children at a higher risk for developing asthma.
Chlorinated pool air exposure is linked to mucosal irritation and asthma-like symptoms in swimmers
Orthopedics & Sports Medicine Sys. Review
Chlorinated pool air exposure is linked to mucosal irritation and asthma-like symptoms in swimmers Chlorinated pool air may cause asthma like symptoms in swimmers
This mini review synthesizes evidence regarding the impact of chlorinated pool air on competitive swimmers and workers. The authors conclude…
Swimming in chlorinated pools can lead to lung irritation and inflammation, posing a risk for athletes with sensitive airways.
CXCL16/CXCR6 axis exerts bidirectional regulatory influence on neoplasms and inflammatory disorders like asthma
Oncology Sys. Review
CXCL16/CXCR6 axis exerts bidirectional regulatory influence on neoplasms and inflammatory disorders like asthma New Biological Pathways May Help Doctors Treat Cancer and Asthma Better
This narrative review examines the CXCL16/CXCR6 axis as a multifaceted regulator in various pathological processes, including neoplasms and …
Scientists are looking at how a specific protein pathway can influence both cancer growth and lung inflammation.
Predictors of Polysomnography Progression in Children with Mild Sleep-Disordered Breathing
Pediatrics RCT
Predictors of Polysomnography Progression in Children with Mild Sleep-Disordered Breathing Certain risk factors may signal when children need surgery sooner
Identifying specific risk factors like ADHD and asthma can help clinicians determine which children with mild sleep-disordered breathing req…
New data shows that conditions like asthma and ADHD can make it more likely that a child's snoring and breathing issues will worsen over tim…
Upstream alarmins IL-33 and TSLP emerge as key targets in T2 asthma pathogenesis
Allergy & Immunology Sys. Review
Upstream alarmins IL-33 and TSLP emerge as key targets in T2 asthma pathogenesis New research identifies key triggers behind Type 2 asthma inflammation
This systematic review synthesizes the complex immune network underlying T2 asthma, highlighting epithelial-derived alarmins IL-33 and TSLP …
Scientists have identified specific early signals that trigger the complex immune response in people with Type 2 asthma.
Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases
Primary Care & Family Medicine Meta-analysis
Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases Better health literacy helps people manage chronic diseases more effectively
This meta-analysis of 138 studies found a moderate positive association (r = 0.29, 95% CI: 0.26-0.31) between health literacy and self-care …
Understanding medical information and using digital tools can help people with chronic conditions like diabetes or heart failure manage thei…
Genetic variant identification improves polygenic risk prediction for patients with asthma
Allergy & Immunology Meta-analysis
Genetic variant identification improves polygenic risk prediction for patients with asthma New Genetic Mapping Improves Prediction of Asthma Risk
Researchers investigated genetic variants associated with asthma in a large cohort of individuals of European ancestry. The analysis identif…
Researchers used deep learning to identify 69 new genetic markers for asthma, improving how doctors can predict risk in people of European a…
Over one-third of workers with occupational asthma experience adverse occupational outcomes
Allergy & Immunology Meta-analysis
Over one-third of workers with occupational asthma experience adverse occupational outcomes Over One-Third of Workers with Occupational Asthma Face Job Hardships
This meta-analysis of 3,393 adults with occupational asthma found a pooled prevalence of 35.9% for adverse occupational outcomes (AOO). Sign…
More than one-third of workers with occupational asthma face serious job impacts like unemployment or disability, highlighting the need for …