HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Drug Pipeline
Sys. Review
Mitochondrial-targeted therapies may prevent doxorubicin cardiotoxicity via PANoptosis modulation
New strategies may protect heart health during chemotherapy treatment
This systematic review synthesizes evidence on mitochondrial-targeted strategies for doxorubicin-induced cardiotoxicity. It describes mechan…
Chemotherapy can damage the heart by disrupting mitochondria, but new research identifies several potential ways to shield the heart from th…
Frontiers
Aug 24, 2026
Cardiology
Sys. Review
Ferroptosis regulation via phytochemicals and targeted delivery systems offers potential to mitigate doxorubicin-induced cardiotoxicity
New strategies may protect heart during chemo without reducing cancer fight
This systematic review examines the mechanisms of myocardial ferroptosis during doxorubicin treatment and evaluates various intervention str…
A review reveals innovative ways to shield the heart from doxorubicin damage while keeping its cancer-killing power intact.
Frontiers
Jul 26, 2026