Research across Arthritis
Related studies from across the Arthritis family.
Coumarins and derivatives may protect musculoskeletal health by modulating inflammatory and oxidative mediators
Coumarins may protect bone and joint health in several diseases
This systematic review examines the role of coumarins and their derivatives in managing musculoskeletal diseases including osteoporosis, rhe…
Coumarins and their derivatives may slow the progression of bone and joint diseases by targeting inflammation and specific cellular pathways…
B-cell targeted therapies show durable immune responses in pemphigus vulgaris and myasthenia gravis
New data shows how B-cell therapies treat autoimmune diseases
This systematic review of 24 clinical trials involving more than 3,500 participants evaluates B-cell targeted therapies for various autoimmu…
New research highlights how targeting specific immune cells can provide lasting relief for several different autoimmune conditions.
HLA-B alleles B*39:01, B*13:01, and B*38:02 serve as markers for sulfasalazine-induced SCARs in Asian populations
Genetic markers help predict severe reactions to sulfasalazine medication
This meta-analysis of a multicountry genetic study identifies specific HLA-B alleles as markers for sulfasalazine-induced severe cutaneous a…
New research identifies specific genetic markers that can help predict if patients with arthritis will have a severe skin reaction to sulfas…
Vunakizumab may induce severe ulcerative colitis and hepatic enzyme elevation in patients with psoriatic arthritis
Vunakizumab Linked to Severe Ulcerative Colitis in Single Case
This case report and literature review describes a single case of severe ulcerative colitis and hepatic enzyme elevation following vunakizum…
A single case report shows a patient developed severe ulcerative colitis and high liver enzymes after receiving vunakizumab injections.
ACR20 overestimates treatment effects compared to target-based outcomes in patients with rheumatoid arthritis
New data shows specific goals better track rheumatoid arthritis success
This meta-epidemiological study of 30,778 patients with rheumatoid arthritis evaluates the concordance between ACR response criteria and tar…
New research shows that some common ways of measuring rheumatoid arthritis progress may overestimate how well a treatment is actually workin…
Exercise improves physical function and reduces pain in adults with rheumatoid arthritis
Exercise Shows Small Gains for Rheumatoid Arthritis
This meta-analysis of 20 studies involving 1487 participants for physical function and 14 studies involving 998 participants for pain indica…
Exercise may slightly improve physical function and pain in rheumatoid arthritis, but more research is needed.
CDAI and SDAI scores improve prediction of osteoporosis in patients with rheumatoid arthritis
New scores help identify osteoporosis risk in rheumatoid arthritis patients
This guideline provides a cross-sectional analysis of osteoporosis prediction in patients with rheumatoid arthritis. The authors found that …
Specific disease-activity scores can help doctors better identify osteoporosis risk in patients living with rheumatoid arthritis.
Caulophyllum robustum extracts show anti-inflammatory and bone protective activity in preclinical models of rheumatoid arthritis
Caulophyllum robustum Shows Potential Activity Against Rheumatoid Arthritis
This systematic review synthesizes preclinical evidence regarding Caulophyllum robustum components, including triterpenoid saponins and alka…
Early laboratory research suggests that compounds found in Caulophyllum robustum may help manage inflammation and joint damage in rheumatoid…
Adalimumab significantly improves ACR70 and PASI100 outcomes in patients with psoriatic arthritis
Trial data shows adalimumab helps manage psoriatic arthritis symptoms
This meta-analysis of 5,655 patients with psoriatic arthritis found that adalimumab significantly improved multiple clinical markers includi…
New analysis of over 5,000 patients shows the drug adalimumab significantly improves skin and joint symptoms for those with psoriatic arthri…
Engineered nanobodies offer programmable platform to overcome limitations of conventional antibodies in angiogenic diseases
Engineered nanobodies may offer better ways to treat solid tumors
This systematic review examines engineered nanobodies targeting angiogenesis-related pathways for solid tumors and other conditions like wet…
Tiny engineered proteins called nanobodies could overcome the limitations of standard treatments for solid tumors and other blood vessel-rel…
Tailor-made DMARD selection based on autoantibody status does not improve DAS scores in RA
Tailored Treatment Plans Show Similar Results for Rheumatoid Arthritis
This randomized controlled trial of 308 adults with DMARD-naīre Rheumatoid Arthritis found no significant difference in mean DAS trajectorie…
A new trial shows that tailoring initial medications based on autoantibody status does not change clinical outcomes for patients with rheuma…
Inaccessible infrastructure and stigma create significant barriers to WASH access for adults with musculoskeletal disabilities
Identifying Barriers to Water and Sanitation for People with Disabilities
This qualitative systematic review of 19 studies identifies key barriers, facilitators, and interventions regarding water, sanitation, and h…
People with musculoskeletal disabilities face unique barriers like stigma and inaccessible infrastructure when trying to access clean water …