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Home › Conditions › Esophageal Carcinoma

Esophageal Carcinoma

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Esophageal Carcinoma

10 trials tracked for Esophageal Carcinoma: 3 in phase 3 or 4 and 1 with published results. The most-cited published study has 582 citations.

10Trials tracked
3Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 3 Phase 2 6 Other / NA 1
  1. Phase 3 Study of SHR-1210 Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal Cancer Completed · 582 cited
  2. Phase 3 Study of Pembrolizumab (MK-3475) Versus Investigator's Choice Standard Therapy for Participants With Advanced Esophageal/ Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181) Completed
  3. Phase 3 Study of Pembrolizumab (MK-3475) Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal/Esophagogastric Junction Carcinoma That Progressed After First-Line Therapy (MK-3475-181/KEYNOTE-181)-China Extension Study Completed
  4. Phase 2 Chemoradiation and Tetrathiomolybdate (TM) in Patients With Esophageal Carcinoma Completed
  5. Phase 2 Ursodiol in Treating Patients With Barrett Esophagus and Low-Grade Dysplasia Completed
  6. Phase 2 Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer Completed
Show 4 more trials
  1. Phase 2 Phase II Trial of Preoperative Combined Modality Therapy for Esophageal Carcinoma: Cisplatin-Irinotecan Followed by Radiation Therapy With Concurrent Cisplatin and Irinotecan. Completed
  2. Phase 2 Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer Completed
  3. Phase 2 Study of Pembrolizumab (MK-3475) in Previously-Treated Participants With Advanced Carcinoma of the Esophagus or Esophagogastric Junction (MK-3475-180/KEYNOTE-180) Completed
  4. N/A Staging and Outcome Depending on Surgical Treatment in Adenocarcinomas of the Oesophagogastric Junction Completed

Showing the 10 most-cited and recently-updated of 10 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
SIB-RT plus S-1 improves survival in elderly inoperable esophageal cancer
ENT (Otolaryngology) RCT
SIB-RT plus S-1 improves survival in elderly inoperable esophageal cancer Combination therapy improves survival in older esophageal cancer patients
This phase III multicenter RCT compared simultaneous integrated boost radiotherapy plus oral S-1 (CRTCT) to radiotherapy alone in patients a…
Adding chemo to radiation boosts 5-year survival from 24% to 34% in older patients with inoperable esophageal cancer.
May 1, 2026