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Familial combined hyperlipidemia

Part of Hyperlipidemia

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Hyperlipidemia

Related studies from across the Hyperlipidemia family.

Cerivastatin best for total cholesterol, simvastatin for LDL-C in DKD with hyperlipidemia
Diabetes & Endocrinology Meta-analysis
Cerivastatin best for total cholesterol, simvastatin for LDL-C in DKD with hyperlipidemia Lipid-Lowering Drugs Show Different Benefits for Kidney Disease
A network meta-analysis of 20 RCTs in patients with diabetic kidney disease and hyperlipidemia found that cerivastatin most effectively redu…
A review of 20 trials found that different statins and fenofibrate have unique effects on cholesterol, kidney markers, and heart risks in di…
Narrative review on PCSK9 inhibitors for familial hypercholesterolemia
Drug Pipeline Sys. Review
Narrative review on PCSK9 inhibitors for familial hypercholesterolemia Review explores PCSK9 inhibitors for familial hypercholesterolemia
This narrative review synthesizes evidence on PCSK9 inhibitors, including evolocumab, for familial hypercholesterolemia. The authors discuss…
This review looks at PCSK9 inhibitors like evolocumab for people with familial hypercholesterolemia. It discusses how these drugs work and t…
Case report and review of literature on acute NSTEMI after fluorescein angiography in a 76-year-old woman
Ophthalmology Sys. Review
Case report and review of literature on acute NSTEMI after fluorescein angiography in a 76-year-old woman Rare heart attack possible after fluorescein angiography in older adults with heart disease
This case report and review of the literature describes a 76-year-old woman with hypertension, hyperlipidemia, and type 2 diabetes mellitus …
A 76-year-old woman with heart disease had a heart attack shortly after a dye test, highlighting rare risks.
FDA Approves Crestor (rosuvastatin) for Cardiovascular Risk Reduction in Adults
Cardiology FDA Approval
FDA Approves Crestor (rosuvastatin) for Cardiovascular Risk Reduction in Adults FDA approves Crestor to prevent heart attacks and strokes in certain adults.
FDA approved Crestor (rosuvastatin) to reduce risk of major adverse cardiovascular events in adults without established coronary heart disea…
The FDA approved Crestor (rosuvastatin) to reduce the risk of heart attack, stroke, and related events in adults without heart disease but w…
Pitavastatin lowers LDL and MACE risk in people with HIV on stable antiretroviral therapy
Infectious Disease RCT
Pitavastatin lowers LDL and MACE risk in people with HIV on stable antiretroviral therapy This cholesterol drug cuts heart risk for people with HIV
This secondary analysis of a phase 3 trial examined pitavastatin versus placebo in people with HIV aged 40 to 75 years on stable antiretrovi…
A large trial found that a daily statin cut heart risk by more than a third in people with HIV, even when their cholesterol looked fine.
Exploratory analysis of RYGB and SG shows variable LDL cholesterol response in patients with obesity and high LDL cholesterol
Nutrition & Obesity Medicine RCT
Exploratory analysis of RYGB and SG shows variable LDL cholesterol response in patients with obesity and high LDL cholesterol Two bariatric surgeries lower cholesterol through completely different biological paths
This exploratory analysis of a randomized clinical trial (BASALTO) evaluated 30 patients with obesity and high LDL cholesterol undergoing Ro…
New research shows that two popular weight loss surgeries lower bad cholesterol in very different ways that could change how doctors pick a …
Essential phospholipids reduced hepatic steatosis and improved HbA1c in patients with MASLD and type 2 diabetes over 6 months
Diabetes & Endocrinology RCT
Essential phospholipids reduced hepatic steatosis and improved HbA1c in patients with MASLD and type 2 diabetes over 6 months Essential Phospholipids Reduce Liver Fat In Six Months
This randomised, placebo-controlled phase 4 trial enrolled 193 patients with metabolic dysfunction-associated steatotic liver disease and ty…
Essential phospholipids may lower liver fat and improve energy levels for people with fatty liver disease and diabetes within just six month…
Surgical treatment for gouty tophi wounds associated with high healing rates in retrospective study
Orthopedics & Sports Medicine Cohort
Surgical treatment for gouty tophi wounds associated with high healing rates in retrospective study Surgery may help heal gouty tophi wounds
This retrospective cohort study of 130 patients with gouty tophi wounds in China observed high wound healing rates following surgical interv…
A small study shows that surgical treatment, including wound cleaning and vacuum drainage, helped most patients with gouty tophi wounds heal…
Lipid lowering therapy patterns in patients with ASCVD and familial hypercholesterolemia in Israel
Cardiology Cohort
Lipid lowering therapy patterns in patients with ASCVD and familial hypercholesterolemia in Israel Lipid lowering therapy patterns observed in Israeli patients
This retrospective database study examined lipid lowering therapy patterns among patients with atherosclerotic cardiovascular disease, ASCVD…
A look at how patients with high cholesterol and heart disease manage their lipid lowering therapy and treatment adherence in Israel.
Systematic review of observational data shows wide variation in primary care discontinuation of lipid-lowering and antihypertensive therapies
Primary Care & Family Medicine Sys. Review
Systematic review of observational data shows wide variation in primary care discontinuation of lipid-lowering and antihypertensive therapies Millions of heart patients stop or restart key medicines at alarming rates in primary care
This systematic review of observational data analyzed 9,146,252 patients in primary care regarding discontinuation and restarting of lipid-l…
Nearly one million patients in primary care stopped or restarted heart medicines within a year, with rates varying widely by age and backgro…
Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
Drug Pipeline Meta-analysis
Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions Ancient Herbs May Help Modern Health
This systematic review synthesizes data on Rhaponticum species, covering 24 documented species worldwide and their applications for conditio…
Imagine walking through a garden filled with wildflowers.
Phase 4 study of evolocumab safety and tolerability in renal transplant recipients
Diabetes & Endocrinology Phase IV
Phase 4 study of evolocumab safety and tolerability in renal transplant recipients Can a new cholesterol drug help kidney transplant patients without causing harm?
This Phase 4 study evaluated the safety and tolerability of evolocumab, a PCSK-9 inhibitor, in renal transplant recipients at three hospital…
A new cholesterol injection kept kidney transplant patients safe for over two years without serious side effects, offering a potential alter…