Case report details multimodal treatment for aggressive thyroid carcinoma
First new treatment combination in six months stabilizes advanced thyroid cancer
A 61-year-old man with papillary thyroid carcinoma achieved disease stabilization after thyroidectomy, radiotherapy, and targeted therapy. T…
A 61-year-old man with advanced thyroid cancer saw his disease stop growing after a specific mix of treatments within six months of his diag…
RAI therapy shifts hyperthyroidism to hypothyroidism in HRAS-mutated HGDTC with hyperfunctioning metastases
Radioactive iodine therapy helped one patient with rare thyroid cancer metastases
A case report and literature review describes a 68-year-old woman with HRAS-mutated high-grade differentiated thyroid carcinoma (HGDTC) and…
Radioactive iodine therapy successfully treated a rare case of thyroid cancer that had spread to the lungs and bones while overproducing hor…
Research across Cancer
Related studies from across the Cancer family.
WBRT shows no significant survival benefit in thyroid cancer brain metastases meta-analysis
Whole-brain radiation shows no clear survival benefit for thyroid cancer brain metastases
A systematic review and individual patient data meta-analysis of 247 patients with thyroid cancer brain metastases found whole-brain radiati…
Whole-brain radiation therapy showed no clear survival benefit for patients with thyroid cancer that spread to their brain.
Follicular T cell subsets and tertiary lymphoid structures may guide immunotherapy in ovarian cancer
New immune targets offer hope for ovarian cancer patients
This narrative review synthesizes evidence on follicular T cell subsets, tertiary lymphoid structures, and other immune features in ovarian …
A review highlights new immune system features that could help doctors predict treatment success and find better ways to fight ovarian cance…
Nivolumab monotherapy yielded 12-month progression-free survival in metastatic anaplastic thyroid cancer
Off-label immunotherapy may help some patients with metastatic anaplastic thyroid cancer
This case report describes a 76-year-old female with metastatic anaplastic thyroid cancer treated with off-label nivolumab monotherapy. The …
A single case report suggests off-label nivolumab helped a 76-year-old woman live longer with metastatic anaplastic thyroid cancer.
Intensity-modulated radiotherapy reduces acute and delayed G2+GI toxicities versus 3D-CRT in high-risk prostate cancer
Post hoc analysis shows IMRT reduces radiation side effects for high-risk prostate cancer
This post hoc analysis of a Phase III randomized controlled trial evaluated intensity-modulated radiotherapy (IMRT) versus three-dimensional…
A post hoc analysis of a Phase III trial found that intensity-modulated radiotherapy reduced radiation side effects compared to older techni…
Meta-analysis finds germline LTS and somatic TERT variants are mutually exclusive in thyroid cancer and melanoma
Two different cancer drivers do not appear together in these tumors
This meta-analysis of retrospective observational cohorts examined germline long-telomere syndrome variants and somatic TERT promoter altera…
A large review of nearly 2,000 adults with thyroid cancer or melanoma found that two specific genetic changes never occur in the same tumor.
Case report of YL205 antibody-drug conjugate in platinum-resistant ovarian carcinoma
First patient achieves complete response with new ovarian cancer drug YL205
This is a single-patient case report of a 40-year-old woman with platinum-resistant, BRCA-wildtype high-grade serous ovarian carcinoma treat…
A single patient with advanced ovarian cancer achieved a complete response after 24 weeks of treatment with YL205, a new antibody-drug conju…
Time to biochemical progression predicts second events in high-risk prostate cancer
Longer time to progression predicts better outcomes in prostate cancer
This phase 3 RCT of 413 men with high-risk localized prostate cancer found that a longer time from randomization to biochemical progression …
Men with high-risk prostate cancer who had a longer time before their cancer worsened were less likely to have further progression or spread…
Symptom Network Changes in Differentiated Thyroid Cancer Patients Undergoing Radioactive Iodine Therapy
Radioactive iodine therapy changes how symptoms connect in patients
This prospective cohort study of 520 patients with differentiated thyroid cancer found that radioactive iodine therapy significantly reorgan…
New research shows that radioactive iodine therapy reshapes how physical and psychological symptoms interact in people with thyroid cancer.
Trastuzumab emtansine and trastuzumab deruxtecan use in three patients with ERBB2-amplified rare tumors
Rare tumors respond to targeted antibody drug treatments
This retrospective case series evaluated three patients with ERBB2-amplified rare tumors, including periampullary, salivary duct, and poorly…
Three patients with rare, aggressive cancers saw significant tumor shrinkage after receiving targeted antibody drug therapies.
Central lymph node ratio threshold predicts lateral lymph node metastasis in pediatric differentiated thyroid carcinoma
One Number Might Predict Thyroid Cancer Spread in Children
This retrospective cohort study evaluated pediatric patients with differentiated thyroid carcinoma aged ≤14 years.
A simple number helps doctors predict if thyroid cancer will spread to side neck nodes in children under 14 years old.
Recurrence patterns in high-grade glioma after standard chemoradiotherapy: a retrospective review
Why tumors grow back inside the radiation beam, not just at the edges
This retrospective single-center review of 41 patients with high-grade glioma found that central recurrence was the most common pattern (36.…
New data shows brain tumors often return in the middle of the radiation zone, suggesting biology, not just targeting errors, drives failure.
TIRADS and Bethesda systems predict thyroid malignancy in 70 patients at Baghdad Teaching Hospital
Family history and neck swelling signal higher risk of thyroid cancer
This prospective cross-sectional study evaluated 70 patients with thyroid complaints at Baghdad Teaching Hospital.
A new look at thyroid nodules shows that family history and neck swelling are key signs of cancer, helping doctors catch it sooner.