Research across Stroke
Related studies from across the Stroke family.
Intracranial hemorrhage rates were higher in tenecteplase than standard care at 14.4% versus 9.2% in minor ischemic stroke
Even small bleeds after minor stroke raise death risk in this trial analysis
This secondary analysis of a multicenter randomized controlled trial evaluated 865 patients with minor ischemic stroke within 12 hours of sy…
A look at trial data shows that small bleeds after minor stroke are linked to higher death rates, even if they do not worsen long-term funct…
Stroke scale expansions improve posterior circulation deficit detection
New tools help doctors spot brain issues in the back part of the head better than old methods
Expanded NIHSS and posterior-specific tools enhance sensitivity for posterior stroke deficits, aiding bedside assessment and prognostic stra…
Doctors are using new scales to find strokes in the back of the brain. These tools work better than the standard ones used today.
Systematic review and meta-analysis on EVT for anterior circulation LVO with low ASPECTS
Stroke patients regain independence years after clot removal procedure
This systematic review and meta-analysis synthesized evidence on endovascular thrombectomy for patients with anterior circulation large vess…
A clot-removal procedure that already helps severe stroke patients at 90 days now shows those benefits hold strong for a full year or more.
Sex differences in outcomes after stroke in NVAF with ASCVD: a post hoc analysis
Women and Men With AFib and Clogged Arteries Share Same Stroke Risk
This post hoc analysis of an RCT included 222 patients with recent ischemic stroke or TIA, NVAF, and ASCVD. No significant sex differences w…
Women and men with AFib and clogged arteries face similar risks for stroke, heart attack, and bleeding over two years.
Meta-analysis finds no benefit of IV thrombolysis for minor ischemic stroke
Clot-busting drugs did not improve function but raised bleeding risk for minor strokes
This systematic review and meta-analysis of RCTs involving 4,361 patients with minor ischemic stroke (NIHSS ≤5) found no significant differe…
A large review found clot-busting drugs offered no benefit for minor strokes but significantly increased the risk of dangerous brain bleedin…
Acupuncture frequency affects aphasia outcomes post-stroke in randomized trial
Does acupuncture speed up speech recovery after stroke, and does the needle speed matter?
This randomized controlled trial in 105 patients with post-ischemic stroke aphasia compared low-frequency and high-frequency acupuncture at …
Slowly twirling acupuncture needles helped stroke patients recover speech and understanding better than fast needles or fake needles after s…
Tenecteplase shows worse functional outcomes in older patients with minor ischemic stroke compared to standard care
The Clot-Busting Drug That Backfires in Patients Over 80
This post hoc analysis of a randomized controlled trial evaluated tenecteplase versus nonthrombolytic standard of care in 884 patients with …
In patients over 80 with minor stroke, a clot-busting drug improved short-term recovery but worsened outcomes at 90 days compared to standar…
PDE5 inhibitors increased cerebral blood flow in white matter hyperintensity regions in adults with cerebral small vessel disease
An Old Drug Class May Protect the Brain From Silent Damage
This systematic review and meta-analysis evaluated phosphodiesterase-5 inhibitors (sildenafil or tadalafil) versus placebo in 236 adults wit…
Drugs already approved for other conditions may help restore blood flow in a part of the brain that quietly fuels strokes and dementia.
Independent risk factors and a predictive nomogram for early neurological deterioration after mechanical thrombectomy in LVO-AIS patients
Why Some Stroke Patients Get Worse After a Successful Brain Procedure
This retrospective cohort study examined 486 patients with acute ischemic stroke due to large vessel occlusion who underwent successful reca…
A new prediction tool helps identify which stroke patients are most at risk of getting worse after successful clot removal, a problem affect…
Intravenous tenecteplase improves functional outcomes but increases hemorrhage risk in non-large vessel occlusion acute ischemic stroke
Tenecteplase improves stroke recovery but increases bleeding risk in late treatment window
This randomized, open-label, blinded end-point trial evaluated intravenous tenecteplase versus standard medical treatment in 570 patients wi…
Tenecteplase helps late-arriving stroke patients recover better but raises bleeding risk, giving doctors a new tool for those beyond the usu…
Protocol for argatroban plus clopidogrel versus aspirin plus clopidogrel in acute minor ischemic stroke
Study will compare two blood thinner combinations for minor strokes
This is a study protocol for a randomized controlled trial of 464 patients with acute minor ischemic stroke (NIHSS ≤5) within 72 hours.
A new trial will test if adding argatroban to clopidogrel leads to better recovery than aspirin plus clopidogrel for minor stroke patients.
Post hoc analysis finds cilostazol reduces stroke recurrence without lowering systolic blood pressure
Study finds cilostazol reduces stroke recurrence without lowering blood pressure
A post hoc mediation analysis of an RCT in 1,795 patients with noncardioembolic ischemic stroke found dual therapy with cilostazol plus…
Cilostazol lowers stroke recurrence risk in patients with prior noncardioembolic strokes without working by dropping their blood pressure.