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Ischemic cardiomyopathy

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Ischemic cardiomyopathy

9 trials tracked for Ischemic cardiomyopathy: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 83 citations.

9Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 2 4 Phase 1 1 Other / NA 3
  1. Phase 3 Ranolazine Implantable Cardioverter-Defibrillator Trial Completed · 83 cited
  2. Phase 2 Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease Completed
  3. Phase 2 Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study) Completed
  4. Phase 2 Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury Completed
  5. Phase 2 Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure Completed
  6. Phase 1 Autologous Stem Cells for Cardiac Angiogenesis (FOCUS HF) Completed
Show 3 more trials
  1. N/A Ablation at Virtual-hEart pRedicted Targets for VT Completed
  2. N/A Contrast ICE for Myocardial Scar in VT Ablations Completed
  3. N/A Feasibility and Effectiveness of Micronutrients as Palliative Care Therapy in Patients With Congestive Heart Failure Completed

Showing the 9 most-cited and recently-updated of 9 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Ischemic cardiomyopathy: what the trials found

In patients with ischemic cardiomyopathy, Ranolazine was evaluated for its impact on ventricular arrhythmias. While there was no statistically significant difference in the total number of patients experiencing ventricular tachycardia (VT), ventricular fibrillation (VF), or death (p=0.117), or those requiring ICD shock for these events (p=0.891), Ranolazine was associated with a significant reduction in the number of recurrent episodes of VT or VF requiring antitachycardia pacing (ATP) or ICD shock therapies (p=0.028) 1.

Recent results — preliminary, needs further review

  • Virtual Heart Guided Ablation was investigated in a small cohort (n=10) 7.

For the clinician treating this condition

  • Ranolazine significantly reduces the frequency of recurrent VT or VF episodes requiring ATP or ICD shock therapies in patients with ischemic cardiomyopathy 1.
  • Ranolazine did not show a statistically significant impact on the total number of patients experiencing VT, VF, or death 1.

AI synthesis of 2 cited trials, updated Sep 7, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.