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Locally advanced renal cell carcinoma

Part of Cancer

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Cancer

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Machine learning predicts Ki-67 in renal tumors with moderate accuracy, AUC 0.85 to 0.86
Radiology & Imaging Meta-analysis
Machine learning predicts Ki-67 in renal tumors with moderate accuracy, AUC 0.85 to 0.86 Machine Learning Models Help Predict Ki-67 in Renal Tumors
This meta-analysis of 7 retrospective cohort studies evaluated machine learning models for noninvasive Ki-67 prediction in renal tumors. Poo…
New machine learning models show promise in predicting Ki-67 levels in renal tumors, offering a potential noninvasive tool to support pathol…
Single-port robot-assisted partial nephrectomy reduces estimated blood loss by 16.62 mL compared to multi-port
Oncology Meta-analysis
Single-port robot-assisted partial nephrectomy reduces estimated blood loss by 16.62 mL compared to multi-port Single Port Surgery Shows Less Blood Loss for Renal Tumors
This meta-analysis of 442 patients with low-complexity renal tumors found that single-port robot-assisted partial nephrectomy (SP-RAPN) resu…
A single-port robotic approach may reduce blood loss during certain kidney tumor surgeries compared to multi-port methods.
Adjunctive hemostatic agents in partial nephrectomy show no transfusion benefit
Oncology Meta-analysis
Adjunctive hemostatic agents in partial nephrectomy show no transfusion benefit Adding topical agents to kidney surgery does not reduce blood loss
This meta-analysis of 3408 patients undergoing partial nephrectomy for T1 renal tumors found no significant difference in blood transfusion …
New data shows that adding certain clotting agents during kidney surgery does not lower the need for blood transfusions or prevent complicat…
Comparative Analysis of Robot Assisted and Laparoscopic Partial Nephrectomy for Renal Tumors
Oncology Meta-analysis
Comparative Analysis of Robot Assisted and Laparoscopic Partial Nephrectomy for Renal Tumors Robot-assisted surgery shows fewer complications for certain kidney tumors
A meta-analysis of 6,202 patients suggests robot-assisted partial nephrectomy offers comparable oncologic outcomes with superior renal prese…
A large review suggests robot-assisted surgery may lead to less blood loss and better kidney function for patients with specific renal tumor…
Robot-assisted radical nephrectomy reduces conversion rates and blood loss compared to laparoscopic surgery for complex tumors
Oncology Meta-analysis
Robot-assisted radical nephrectomy reduces conversion rates and blood loss compared to laparoscopic surgery for complex tumors Robot-assisted Surgery Shows Benefits for Complex Renal Tumors
This meta-analysis of 4,163 patients evaluated robot-assisted radical nephrectomy (RARN) versus laparoscopic radical nephrectomy (LRN) for h…
Robotic surgery may reduce blood loss and the need for transfusions while preserving kidney function in patients with complex renal tumors.
Case review of epithelial-type Wilms tumor in a 23-year-old female with clear surgical margins
Oncology Sys. Review
Case review of epithelial-type Wilms tumor in a 23-year-old female with clear surgical margins A rare kidney tumor in a young adult was removed with clear margins and no spread
This case review describes a 23-year-old female who underwent right radical nephrectomy for a rare epithelial-type Wilms tumor. Histopatholo…
A 23-year-old woman had a rare kidney tumor removed. The surgery showed clear edges and no spread. This case highlights the need for awarene…
Ultrasound-guided salvage brachytherapy with interstitial hyperthermia shows low toxicity in locally recurrent prostate cancer
Urology Phase II
Ultrasound-guided salvage brachytherapy with interstitial hyperthermia shows low toxicity in locally recurrent prostate cancer New prostate cancer treatment shows low side effects after 5 years
This prospective phase 2 trial evaluated ultrasound-guided salvage brachytherapy with interstitial hyperthermia in 109 patients with locally…
A new treatment for recurrent prostate cancer kept 93% of patients alive at 5 years with very low serious side effects.
Kidney-directed SBRT shows modest renal function decline in inoperable patients
Nephrology Phase II
Kidney-directed SBRT shows modest renal function decline in inoperable patients Small study shows kidney function drops after radiation for hard-to-treat tumors
This prospective phase 2 single-arm trial evaluated kidney-directed SBRT in 30 patients with primary or metastatic renal tumors who were med…
Radiation to treat kidney tumors may lower kidney function over two years, even when surgery is not an option.
Nephrometry Scores Show Limited Discrimination for Adverse Outcomes After RAPN in Larger Renal Tumors
Nephrology Cohort
Nephrometry Scores Show Limited Discrimination for Adverse Outcomes After RAPN in Larger Renal Tumors Tumor complexity scores predict longer surgery time but not major complications in kidney cancer removal
This retrospective cohort study of 109 patients with pT1b–pT2a renal tumors found that PADUA and RENAL nephrometry scores had limited discri…
Scores measuring kidney tumor complexity predicted longer surgery time but failed to predict major complications in 109 patients.
Meta-analysis shows percutaneous irreversible electroporation plus immunotherapy improves outcomes in locally advanced pancreatic cancer
Oncology Meta-analysis
Meta-analysis shows percutaneous irreversible electroporation plus immunotherapy improves outcomes in locally advanced pancreatic cancer Adding immunotherapy to ablation therapy extends life for pancreatic cancer patients
This systematic review and meta-analysis evaluated percutaneous irreversible electroporation combined with immunotherapy versus irreversible…
Adding immune therapy to ablation therapy helps patients live longer with locally advanced pancreatic cancer without causing more side effec…
Retrospective review finds higher ORR with salvage DCRT in locally advanced ESCC
Oncology Guideline
Retrospective review finds higher ORR with salvage DCRT in locally advanced ESCC Salvage therapy works better than upfront treatment for some esophageal cancer patients
This retrospective analysis of 91 patients from 3 medical centers compared salvage versus upfront definitive chemoradiotherapy (DCRT) for lo…
New data shows treating esophageal cancer after a failed first attempt may lead to better outcomes than starting with the strongest drugs im…
Systematic review finds neoadjuvant chemohormonal therapy improves biochemical progression-free survival in locally advanced prostate cancer
Oncology Meta-analysis
Systematic review finds neoadjuvant chemohormonal therapy improves biochemical progression-free survival in locally advanced prostate cancer Chemo Before Prostate Surgery Linked to Better Cancer Control
This systematic review and meta-analysis evaluated neoadjuvant chemohormonal therapy (NCHT) combined with radical prostatectomy versus radic…
Patients with advanced prostate cancer may see better cancer control with chemo before surgery, though survival gains need more proof.