Research across Cancer
Related studies from across the Cancer family.
Case review of epithelial-type Wilms tumor in a 23-year-old female with clear surgical margins
A rare kidney tumor in a young adult was removed with clear margins and no spread
This case review describes a 23-year-old female who underwent right radical nephrectomy for a rare epithelial-type Wilms tumor. Histopatholo…
A 23-year-old woman had a rare kidney tumor removed. The surgery showed clear edges and no spread. This case highlights the need for awarene…
Ultrasound-guided salvage brachytherapy with interstitial hyperthermia shows low toxicity in locally recurrent prostate cancer
New prostate cancer treatment shows low side effects after 5 years
This prospective phase 2 trial evaluated ultrasound-guided salvage brachytherapy with interstitial hyperthermia in 109 patients with locally…
A new treatment for recurrent prostate cancer kept 93% of patients alive at 5 years with very low serious side effects.
Kidney-directed SBRT shows modest renal function decline in inoperable patients
Small study shows kidney function drops after radiation for hard-to-treat tumors
This prospective phase 2 single-arm trial evaluated kidney-directed SBRT in 30 patients with primary or metastatic renal tumors who were med…
Radiation to treat kidney tumors may lower kidney function over two years, even when surgery is not an option.
Nephrometry Scores Show Limited Discrimination for Adverse Outcomes After RAPN in Larger Renal Tumors
Tumor complexity scores predict longer surgery time but not major complications in kidney cancer removal
This retrospective cohort study of 109 patients with pT1b–pT2a renal tumors found that PADUA and RENAL nephrometry scores had limited discri…
Scores measuring kidney tumor complexity predicted longer surgery time but failed to predict major complications in 109 patients.
Meta-analysis shows percutaneous irreversible electroporation plus immunotherapy improves outcomes in locally advanced pancreatic cancer
Adding immunotherapy to ablation therapy extends life for pancreatic cancer patients
This systematic review and meta-analysis evaluated percutaneous irreversible electroporation combined with immunotherapy versus irreversible…
Adding immune therapy to ablation therapy helps patients live longer with locally advanced pancreatic cancer without causing more side effec…
Retrospective review finds higher ORR with salvage DCRT in locally advanced ESCC
Salvage therapy works better than upfront treatment for some esophageal cancer patients
This retrospective analysis of 91 patients from 3 medical centers compared salvage versus upfront definitive chemoradiotherapy (DCRT) for lo…
New data shows treating esophageal cancer after a failed first attempt may lead to better outcomes than starting with the strongest drugs im…
Systematic review finds neoadjuvant chemohormonal therapy improves biochemical progression-free survival in locally advanced prostate cancer
Chemo Before Prostate Surgery Linked to Better Cancer Control
This systematic review and meta-analysis evaluated neoadjuvant chemohormonal therapy (NCHT) combined with radical prostatectomy versus radic…
Patients with advanced prostate cancer may see better cancer control with chemo before surgery, though survival gains need more proof.
Radical nephrectomy performed for renal inflammatory myofibroblastic tumor in an elderly female
Rare Kidney Tumor Treated Successfully With Surgery Alone
This is a case report of an elderly female patient who underwent radical right nephrectomy for a renal inflammatory myofibroblastic tumor.
A rare kidney tumor was removed with surgery, and no recurrence was seen at 6 months. But this is just one case.
Savolitinib and durvalumab combination yields response rates of 34% to 53% in papillary renal cancer patients
New Hope for a Tough Kidney Cancer Type
This single-arm phase II study evaluated savolitinib and durvalumab in 41 treatment-naïve or pretreated patients with papillary renal cancer…
A new drug pair breaks the shield blocking treatment for a rare kidney cancer type, offering patients a chance at longer survival after stan…
Review of case report showing durable response after surgery in metastatic bladder SqCC
She Was Offered Hospice. Surgery Gave Her Two More Years Instead
This narrative review synthesizes a single case report of a 65-year-old woman with metastatic squamous cell carcinoma of the bladder.
A woman with a rare, drug-resistant bladder cancer that had spread to both lungs chose surgery when hospice was offered — and two years late…
Curative-intent local therapy linked to improved survival in isolated contralateral axillary breast metastasis
Local therapy linked to better survival in advanced breast cancer patients with specific metastases
This retrospective cohort study of 1110 patients across two tertiary centers compared outcomes in isolated contralateral axillary metastasis…
Patients with specific breast cancer spread to the opposite armpit survived longer when receiving surgery or radiation compared to systemic …
Simlukafusp alfa plus atezolizumab with or without bevacizumab shows antitumor activity in metastatic renal cell carcinoma
Does adding bevacizumab nearly triple the time before kidney cancer grows back?
A phase Ib randomized open-label study in 66 patients with metastatic renal cell carcinoma found objective response rates of 25% with simluk…
Adding bevacizumab nearly tripled the time before kidney cancer grew back compared to a two-drug mix in this early study.