Research across Cancer
Related studies from across the Cancer family.
Comprehensive diagnostic evaluation identifies HPV-associated squamous cell carcinoma in a patient with a pelvic mass
HPV Testing Helps Identify Source of Pelvic Squamous Cell Carcinoma
This case report describes a 55-year-old woman with a pelvic mass and a squamous cell carcinoma. The report highlights the utility of integr…
A single case report shows how combining imaging and HPV testing can help doctors identify the source of a pelvic tumor.
Camrelizumab plus chemotherapy is cost-effective for first-line treatment of advanced squamous non-small-cell lung cancer
Immune Checkpoint Inhibitors Show Cost-Effectiveness for Lung Cancer Treatment
This network meta-analysis evaluates the cost-effectiveness of six immune checkpoint inhibitor-based first-line therapies combined with chem…
New analysis shows specific immune checkpoint inhibitor combinations may be more cost-effective than chemotherapy for advanced lung cancer p…
Intersphincteric resection reduces local recurrence and improves five-year survival in lower rectal cancer
Intersphincteric resection shows better outcomes for lower rectal cancer
This meta-analysis of retrospective studies evaluates intersphincteric resection (ISR) compared to abdominoperineal resection (APR) for lowe…
A new analysis shows that intersphincteric resection can lower complication rates and improve survival for patients with lower rectal cancer…
Artificial Intelligence Performance in Dermatoscopic Image Interpretation for Skin Cancer Diagnosis
AI Shows High Performance in Detecting Skin Cancer Images
A meta-analysis of 208 articles evaluates how AI compares to expert dermatoscopy in identifying melanoma and other common skin malignancies.
Artificial intelligence may improve the accuracy of diagnosing skin cancers like melanoma when analyzing specialized skin images.
Immunotherapy regimens for TKI-resistant NSCLC are not cost-effective without significant price reductions
New lung cancer treatments show better results but higher costs
This network meta-analysis evaluated the cost-effectiveness of three immunotherapy-based combinations compared to chemotherapy in patients w…
Newer drug combinations offer better survival for certain lung cancer patients, but high costs currently make them difficult to fund widely.
EGFR and TP53 mutations linked to worse survival in sinonasal squamous cell carcinoma
Genetic markers linked to survival in sinonasal squamous cell carcinoma
A meta-analysis of 25 retrospective cohort studies including 1194 patients with sinonasal squamous cell carcinoma found that EGFR and TP53 m…
Specific genetic mutations and protein levels can help doctors predict how patients with certain head and neck cancers will respond to treat…
Diverse therapeutic approaches including immunotherapy are utilized for patients with occult squamous cell carcinoma
Men and women show different patterns in squamous cell carcinoma
This systematic review of case reports examines clinical characteristics and treatment strategies for patients with occult squamous cell car…
New data shows that men and women experience different locations for lymph node spread in certain types of skin cancer.
Actinic keratosis increases melanoma risk while alcohol consumption is associated with lower squamous cell carcinoma risk
Actinic Keratosis Linked to Higher Risk of Melanoma
This meta-analysis of genome-wide association studies evaluates causal relationships between 11 modifiable risk factors and skin cancers. Th…
New research identifies a link between actinic keratosis and melanoma risk while highlighting potential new targets for skin cancer treatmen…
Sugar sweetened beverages and orange juice are associated with increased risk of several cancer types
Sugar sweetened drinks may increase risk of several cancer types
This meta-analysis of 51 cohort studies evaluates the link between sugar sweetened beverages (SSBs), artificially sweetened beverages (ASBs)…
New research suggests a link between sugar-sweetened beverages and an increased risk of certain cancers, including pancreatic and colorectal…
EGFR inhibitors show reproducible activity and manageable toxicity in locally advanced or metastatic anal squamous cell carcinoma
EGFR Inhibitors Show Activity in Advanced Anal Squamous Cell Carcinoma
This meta-analysis of 404 patients evaluated EGFR inhibitors (cetuximab and panitumumab) for anal squamous cell carcinoma. The analysis foun…
New analysis shows that EGFR inhibitors like cetuximab and panitumumab may improve response rates for patients with advanced anal squamous c…
Trastuzumab deruxtecan and pyrotinib provide disease control in lung squamous cell carcinoma with ERBB2 mutation
New Treatment Strategy Shows Promise for Lung Squamous Cell Carcinoma
This case report describes a patient with stage IA2 lung squamous cell carcinoma and an ERBB2 exon 20 p.G776V mutation treated with trastuzu…
A new treatment plan using trastuzumab deruxtecan and pyrotinib showed promising results for a patient with a specific lung cancer mutation.
Transitioning from static TNM staging to a multidimensional, adaptive treatment model integrating genomics and immunology for HPV-associated OPSCC
Doctors are shifting from static staging to adaptive care for HPV throat cancer
This narrative review discusses the evolving management of HPV-associated oropharyngeal squamous cell carcinoma. The authors argue for trans…
Medical teams are moving away from old staging rules toward a new model that uses genomics and immunology for precise care.