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Infectious Disease
Sys. Review
Beta-lactam/beta-lactamase inhibitor therapy reduces all-cause mortality in multidrug-resistant Gram-negative infections
Combination Therapy Shows Better Outcomes for Gram-Negative Infections
This systematic review and network meta-analysis of 1760 patients found that beta-lactam/beta-lactamase inhibitor therapy significantly redu…
Combining certain antibiotics may lower death rates and reduce kidney damage for patients with multidrug-resistant Gram-negative infections.
Sep 3, 2026
Infectious Disease
Cohort
Tigecycline monotherapy shows no outcome disadvantage versus combination therapy for MDR gram-negative infections in retrospective cohort
Study finds no clear benefit of combination therapy over tigecycline alone for resistant infections
A retrospective cohort study of 280 hospitalized adults with MDR gram-negative infections found no independent association between tigecycli…
Combining antibiotics with tigecycline offers no clear benefit over using the drug alone for treating severe, drug-resistant bacterial infec…
Frontiers
Apr 4, 2026