Complete revascularization shows high probability of benefit for NSTEMI patients with multivessel disease
Complete revascularization shows high probability of benefit for NSTEMI patients with multivessel disease
This Bayesian re-analysis of a randomized trial evaluated complete versus culprit-only revascularization in patients with non-ST-elevation m…
A Bayesian re-analysis suggests complete revascularization offers a high probability of clinically meaningful benefit compared to treating o…
Meta-analysis shows no significant difference between immediate and staged revascularization for STEMI with multivessel disease
Immediate heart procedure shows no major benefit over staged approach for heart attack patients
This systematic review and meta-analysis evaluated patients with ST-elevation myocardial infarction and multivessel disease undergoing immed…
A large review of heart attack patients with multiple blocked arteries found that doing the full procedure right away did not lower the risk…
iFR-guided CABG improves mid-term graft patency versus angiography alone in multivessel disease
Can a simple test during heart surgery help grafts stay open longer?
A single-blinded RCT in patients with multivessel disease and intermediate stenoses found iFR-guided CABG significantly improved LIMA-to-LAD…
A simple pressure test during heart surgery keeps new blood vessel grafts open longer, with 80.5% staying clear versus 56.8% with standard i…
Meta-analysis finds 2% mean prevalence of class 1 revascularization indications in prekidney transplant CAD screening
Pre-kidney transplant heart screening rarely finds severe blockages needing immediate surgery
A meta-analysis of 44 prekidney transplant screening studies found a mean 2% prevalence of American Heart Association class 1 indications fo…
Most people screened before kidney transplants do not have severe heart blockages requiring immediate surgery, according to a review of 44 s…
Immediate revascularization tied to higher 1-year risk in STEMI with multivessel disease and heart failure
For heart attack patients with heart failure, does fixing all blockages right away help or hurt?
In the OPTION-STEMI trial, immediate complete revascularization was not non-inferior to staged revascularization.
For heart attack patients with heart failure, fixing all blockages immediately raises the risk of death or another heart attack within a yea…
Research across Myocardial ischemia
Related studies from across the Myocardial ischemia family.
Staged revascularization shows no significant difference versus immediate revascularization for major adverse cardiovascular events in STEMI and MVD patients
Timing of heart surgery does not change survival for a specific heart attack group
This meta-analysis reviewed 5077 patients with ST-segment elevation myocardial infarction and multivessel coronary artery disease comparing …
A large review found that waiting for staged heart surgery did not improve survival or reduce heart attacks compared to immediate surgery fo…
Five-year economic and quality of life outcomes favor PCI with zotarolimus stents over CABG in 3-vessel CAD
Five-year follow-up reveals lower costs and better employment for PCI over surgery in complex heart disease
This randomized trial compared fractional flow reserve-guided PCI using zotarolimus drug-eluting stents with coronary artery bypass grafting…
Patients with complex heart disease treated with stents had lower costs and better quality of life than those who had surgery after five yea…
FFR-guided complete revascularization reduces unplanned revascularization in MI patients with multivessel CAD
Complete Heart Repair May Stop Future Emergencies
A meta-analysis of 3,054 patients with myocardial infarction and multivessel coronary artery disease found that FFR-guided complete revascul…
Fixing all blocked heart arteries during surgery may stop future emergencies and unplanned procedures for patients with heart attacks.
Ticagrelor Not Noninferior to Prasugrel in Diabetes Patients With Multivessel CAD After PCI
New study shows ticagrelor did not beat prasugrel for heart attack prevention in diabetics
This randomized clinical trial of 1,800 patients with diabetes and multivessel coronary artery disease undergoing PCI compared ticagrelor pl…
For diabetics with heart stents, a new study found ticagrelor offered no clear advantage over prasugrel in preventing death, heart attacks, …
Questions about Multivessel Disease
What is the risk of immediate complete revascularization versus staged revascularization for my heart attack?
For most patients with STEMI and multivessel disease, immediate and staged revascularization have similar risks of death or heart attack, but staged may reduce the need for repeat procedures.
Full answer →Is there a difference between immediate and staged surgery for STEMI with multivessel disease?
For STEMI with multivessel disease, immediate and staged revascularization show similar outcomes overall, but staged may be safer in patients with heart failure or cardiogenic shock.
Full answer →Does immediate surgery help or hurt STEMI patients with multivessel disease and heart failure?
Immediate surgery does not improve outcomes for all STEMI patients with multivessel disease, and it may increase risks for those with heart failure.
Full answer →