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Home › Conditions › Myocardial Fibrosis

Myocardial Fibrosis

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Myocardial Fibrosis

2 trials tracked for Myocardial Fibrosis: 2 in phase 3 or 4 and 2 with published results. The most-cited published study has 80 citations.

2Trials tracked
2Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 2
  1. Phase 4 Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy Completed · 80 cited
  2. Phase 4 Effects of SGLT-2 Inhibition on Myocardial Fibrosis and Inflammation as Assessed by Cardiac MRI in Patients With DM2 Completed · 52 cited

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
HIV infection is associated with significantly higher myocardial fibrosis markers in patients living with HIV
Cardiology Meta-analysis
HIV infection is associated with significantly higher myocardial fibrosis markers in patients living with HIV HIV infection is linked to increased heart muscle scarring
This meta-analysis of 13 studies indicates that patients living with HIV exhibit significantly higher late gadolinium enhancement (OR: 5.47)…
New data shows that people living with HIV have significantly higher levels of heart tissue scarring compared to healthy individuals.
medRxiv Sep 30, 2026
Traditional Chinese Medicine modulates mitochondrial quality control to potentially address myocardial fibrosis
Cardiology Sys. Review
Traditional Chinese Medicine modulates mitochondrial quality control to potentially address myocardial fibrosis Traditional Chinese Medicine May Help Protect Heart Tissue from Scarring Damage
This systematic review synthesizes evidence regarding Traditional Chinese Medicine (TCM) monomers and formulas in the context of myocardial …
New research looks at how traditional herbal formulas might protect heart cells and improve energy production in patients with heart scarrin…
Frontiers Sep 29, 2026
Systematic review examines programmed cell death roles in myocardial fibrosis mechanisms
Cardiology Sys. Review
Systematic review examines programmed cell death roles in myocardial fibrosis mechanisms Review links cell death types to heart scarring processes
This systematic review investigated the roles of various programmed cell death types in myocardial fibrosis.
Different types of programmed cell death drive heart scarring by activating fibroblasts and altering the heart's structural material, offeri…
Frontiers Apr 9, 2026
Review suggests TWEAK-Fn14 axis contributes to brain injury and cardiac dysfunction pathology
Cardiology Sys. Review
Review suggests TWEAK-Fn14 axis contributes to brain injury and cardiac dysfunction pathology Review explores protein link between brain and heart diseases
A systematic review summarizes evidence on the TWEAK-Fn14 signaling pathway in cardio-cerebrovascular diseases.
High levels of two specific proteins linked to brain swelling and heart scarring may offer a future target for treating brain-heart syndrome…
Frontiers Apr 2, 2026

Questions about Myocardial Fibrosis

Does the TWEAK-Fn14 axis contribute to myocardial fibrosis?

The TWEAK-Fn14 axis is implicated in several pathological processes in the heart, including inflammation, hypertrophy, and fibrosis.

Full answer →
Can Traditional Chinese Medicine help treat myocardial fibrosis?

Traditional Chinese Medicine (TCM) shows promise in research for treating myocardial fibrosis by targeting specific cellular pathways and improving mitochondrial health.

Full answer →