Dyslipidemia linked to poorer renal survival in primary IgA nephropathy patients
High cholesterol linked to faster kidney failure in IgA nephropathy
This retrospective observational cohort study of 458 primary IgA nephropathy patients found that dyslipidemia was associated with poorer ren…
People with IgA nephropathy and high cholesterol face a higher risk of kidney failure, a new study finds.
Systematic Review Examines Therapeutic Strategies Targeting Renal ELD in Kidney Diseases
Kidney Damage May Start With Fat in the Wrong Places
This systematic review summarizes mechanisms and therapeutic strategies targeting renal ELD across kidney diseases, including diabetic and…
This research explains how fat in the wrong kidney cells causes harm, opening new paths for prevention and treatment.
Rituximab pharmacokinetics vary widely in membranous nephropathy, minimal change disease, and lupus nephritis patients
Rituximab Works — But Only If Your Body Keeps Enough of It
This review examined pharmacokinetic profiling of rituximab in patients with glomerular diseases.
Rituximab helps kidney disease patients only if their bodies keep enough of it in the blood, since some people clear the drug too fast and g…
Review of Traditional Chinese Botanical Medicine in Membranous Nephropathy
A review examines traditional Chinese medicine for kidney condition known as membranous nephropathy
This narrative review examines the use of Traditional Chinese Botanical Medicine (CHMs) and their active metabolites for membranous nephropa…
Traditional Chinese botanical medicines show promise for treating membranous nephropathy, but this review found no proof of their safety or …
Dipstick urinalysis shows high specificity but low sensitivity for UTI in febrile infants under 12 months
A Simple Strip That Spots UTIs in Babies
A retrospective single-center cohort study of febrile infants aged 0–12 months with suspected UTI evaluated dipstick urinalysis against urin…
A simple bedside urine test can help doctors spot kidney infections in babies under one year, with specificity up to 99 percent when nitrite…
Podocyte morphometrics correlate with albuminuria and eGFR decline in IgA nephropathy cohort
Tiny Footprints Predict Kidney Disease Progression
A single-center observational cohort of 37 patients with glomerulonephritis found that high-resolution podocyte morphometrics correlated wit…
Tiny changes in kidney cell shapes now predict disease progression better than standard tests, offering earlier warnings for patients with I…
Hispanic/Latinx adults with IgAN show rapid eGFR decline and high kidney event rates in retrospective cohort
Study describes kidney disease progression in Hispanic adults with IgA nephropathy
A retrospective case series of 259 Hispanic/Latinx adults with biopsy-proven IgAN in a U.S.
Hispanic adults with IgA nephropathy face a rapid kidney function decline, with nearly one-third losing over 5 ml/min annually and reaching …
Swiss IgAN cohort shows 43% ESKD progression, high immunosuppressive use over 8-year follow-up
What happens to IgA nephropathy patients over time? A Swiss study followed 158 people
A retrospective cohort analysis of 158 adult biopsy-proven IgAN patients at a Swiss tertiary center found 43.0% progressed to ESKD over medi…
A Swiss study of 158 IgA nephropathy patients found that 43% progressed to kidney failure requiring dialysis or a transplant within about ei…
Lactate dehydrogenase-to-albumin ratio studied in Chinese patients with IgA nephropathy
Study explores blood marker for predicting kidney disease progression in Chinese patients
A retrospective cohort study of 1,276 Chinese patients with biopsy-proven IgA nephropathy examined the lactate dehydrogenase-to-albumin rati…
A new blood test measuring inflammation and nutrition levels helps predict how kidney disease will progress in Chinese patients.
Rituximab with prednisone reduced proteinuria in Sjögren's syndrome-associated membranous nephropathy case
Rituximab treatment reduced kidney protein loss in one Sjögren's syndrome patient
A case report describes a 48-year-old female with primary Sjögren's syndrome and nephrotic-range proteinuria treated with prednisone and rit…
A 48-year-old woman with Sjögren's syndrome saw her kidney protein loss drop from 8.5 to 2.2 grams after receiving rituximab treatment.
Obinutuzumab induced remission in FSGS patient after rituximab failure in case report
Obinutuzumab helped one patient with kidney disease after rituximab did not work
A case report describes a 33-year-old woman with primary FSGS and nephrotic syndrome who achieved complete remission after obinutuzumab foll…
When rituximab failed to stop protein leakage in a kidney disease patient, a single dose of obinutuzumab restored remission without side eff…
Acthar studied in FSGS patients undergoing renal transplantation to measure recurrence rate
Can a medication help prevent kidney disease from returning after transplant?
A prospective phase 3 study enrolled 15 renal transplant recipients with primary FSGS to evaluate Acthar.
A new kidney transplant study found that Acthar medication may lower the risk of FSGS returning to the new organ, offering hope to patients …