Research across Cancer
Related studies from across the Cancer family.
Hashimoto's thyroiditis functions as a dual-natured immune microenvironment in differentiated thyroid cancer
Hashimoto's thyroiditis may both help and hinder thyroid cancer
This narrative review explores the role of Hashimoto's thyroiditis (HT) in the immune microenvironment of differentiated thyroid cancer. The…
Hashimoto's thyroiditis can act as both a shield and a sword for thyroid cancer, depending on the specific immune environment of the patient…
Individualized treatment planning for synchronous bilateral primary breast cancer is supported by independent lesion characterization
Individualized treatment plans help patients with dual primary breast cancers
This case report and literature review examines 1 case and 7 literature cases of synchronous bilateral primary breast cancer. The authors hi…
Doctors are finding that treating each tumor as a unique case helps patients with cancer in both breasts.
Radioactive iodine does not significantly reduce recurrence in low-risk differentiated thyroid cancer
Radioactive Iodine May Not Prevent Recurrence in Low-Risk Thyroid Cancer
This meta-analysis of 5260 patients evaluated the impact of radioactive iodine on recurrence and survival in low-risk differentiated thyroid…
New data suggests that radioactive iodine may not provide a significant benefit for preventing cancer recurrence in patients with low-risk t…
High tumoral PD-L1 expression correlates with increased local invasion and distant metastases in differentiated thyroid cancer
High PD-L1 levels linked to thyroid cancer spread
This meta-analysis of 12 retrospective studies indicates that high tumoral PD-L1 expression is significantly associated with lymphovascular …
New data shows that high levels of a specific protein can signal if thyroid cancer is more likely to spread locally or to distant parts of t…
Completion thyroidectomy follows total thyroidectomy for similar operative safety in differentiated thyroid cancer
Less surgery may be safer for thyroid cancer patients
This meta-analysis of 43,362 patients evaluated the surgical safety of completion thyroidectomy (CT) compared to upfront total thyroidectomy…
For some thyroid cancers, a less extensive surgery may be safer with fewer complications.
Laryngeal obstruction as initial sign of MEN2B in two pediatric cases with RET mutations
Rare genetic disorder first shows as breathing trouble in children
This case report describes 2 pediatric patients with MEN2B presenting with laryngeal obstruction and progressive respiratory compromise as i…
Two children with a rare genetic condition first showed breathing trouble from nerve growths in the airway, not the usual symptoms.
TSH suppression therapy promotes tumor progression via G-protein signaling pathways in differentiated thyroid cancer
TSH Suppression Therapy Framework for Differentiated Thyroid Cancer
This systematic review synthesizes the biological mechanisms of TSH-mediated tumor progression and proposes a clinical decision-making frame…
New research outlines how TSH levels impact thyroid cancer growth and offers a new decision-making framework for personalized patient care.
I-SPECT/CT shows high patient-level specificity of 0.95 for detecting residual disease in DTC
Imaging technology shows promise for detecting thyroid cancer recurrence
This meta-analysis evaluates the diagnostic efficacy of I-SPECT/CT for identifying residual or recurrent disease in patients with differenti…
A new imaging method called I-SPECT/CT helps doctors find leftover or returning thyroid cancer cells with high accuracy after treatment.
Hemithyroidectomy is associated with a 3% higher risk difference in cancer recurrence rate
Hemithyroidectomy linked to higher thyroid cancer recurrence
This meta-analysis of 98,604 patients with differentiated thyroid carcinoma found that hemithyroidectomy (HT) was associated with a 3% highe…
A large meta-analysis found that hemithyroidectomy for differentiated thyroid cancer has a higher recurrence rate than total thyroidectomy, …
Signet ring morphology in gastric biopsies may mask metastatic invasive lobular carcinoma from breast cancer
Expert Review Helps Identify Breast Cancer Spreading to Stomach
This case report describes a 52-year-old woman with metastatic invasive lobular carcinoma that was initially misidentified as primary gastri…
A single patient's case shows how specific lab tests can help doctors distinguish between stomach cancer and metastatic breast cancer.
WBRT shows no significant survival benefit in thyroid cancer brain metastases meta-analysis
Whole-brain radiation shows no clear survival benefit for thyroid cancer brain metastases
A systematic review and individual patient data meta-analysis of 247 patients with thyroid cancer brain metastases found whole-brain radiati…
Whole-brain radiation therapy showed no clear survival benefit for patients with thyroid cancer that spread to their brain.
Nivolumab monotherapy yielded 12-month progression-free survival in metastatic anaplastic thyroid cancer
Off-label immunotherapy may help some patients with metastatic anaplastic thyroid cancer
This case report describes a 76-year-old female with metastatic anaplastic thyroid cancer treated with off-label nivolumab monotherapy. The …
A single case report suggests off-label nivolumab helped a 76-year-old woman live longer with metastatic anaplastic thyroid cancer.