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Non-ST-elevation myocardial infarction

Part of Myocardial ischemia

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Non-ST-elevation myocardial infarction

3 trials tracked for Non-ST-elevation myocardial infarction: 3 in phase 3 or 4 and 1 with published results. The most-cited published study has 353 citations.

3Trials tracked
3Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 3
  1. Phase 4 Tailored Use of Tirofiban for Non-ST-elevation Acute Coronary Syndrome Patients Completed · 353 cited
  2. Phase 4 Brilinta Taiwan Post Approval Safety Study Completed
  3. Phase 4 Clinical Effects of Eptifibatide Administration in High Risk Patients Presenting With Non-ST Segment Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Urgent Coronary Artery Bypass Graft Surgery in Short- and Long-Term Follow-up Completed

Showing the 3 most-cited and recently-updated of 3 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Myocardial ischemia

Related studies from across the Myocardial ischemia family.

Beta-blocker therapy shows no significant reduction in primary composite outcomes for patients with LVEF ≥ 40%
Cardiology Meta-analysis
Beta-blocker therapy shows no significant reduction in primary composite outcomes for patients with LVEF ≥ 40% Beta-blocker therapy shows mixed results for heart attack patients
This meta-analysis of 18,504 patients with acute myocardial infarction and LVEF ≥ 40% found no significant reduction in the primary composit…
New data suggests beta-blockers may only show a significant benefit for heart attack patients with specific levels of heart muscle function.
Naoxintong Supplementation Reduces Heart Failure Risk Following Acute Myocardial Infarction
Cardiology RCT
Naoxintong Supplementation Reduces Heart Failure Risk Following Acute Myocardial Infarction New treatment may lower heart failure risk after heart attack
A randomized trial suggests that adding Naoxintong to standard therapy significantly reduces heart failure incidence and MACE rates post-AMI…
A new study shows that adding a herbal formula to standard care can significantly reduce heart failure risk for patients after a heart attac…
Clinical signs, imaging, and biomarkers facilitate risk stratification for cardiac rupture in myocardial infarction
Cardiology Sys. Review
Clinical signs, imaging, and biomarkers facilitate risk stratification for cardiac rupture in myocardial infarction New tools help doctors predict life-threatening heart ruptures after heart attacks
This mini review synthesizes clinical warning signs, point-of-care imaging, and biomarker trajectories to stratify risk of cardiac rupture i…
Doctors are developing a new four-step plan to spot early warning signs of heart rupture, a condition where the heart muscle tears during a …
Intravenous nicorandil did not significantly reduce primary composite outcomes in patients with STEMI
Cardiology RCT
Intravenous nicorandil did not significantly reduce primary composite outcomes in patients with STEMI Trial shows intravenous nicorandil does not improve heart attack outcomes
This randomized controlled trial of 1,503 patients with STEMI found no significant difference in the primary composite outcome between intra…
A large trial of over 1,500 patients found that the drug nicorandil did not improve primary outcomes for those with a heart attack.
DeepSeek AI generates guideline-conforming exercise prescriptions for myocardial infarction, heart failure, and atrial fibrillation
Physical Medicine & Rehab Guideline
DeepSeek AI generates guideline-conforming exercise prescriptions for myocardial infarction, heart failure, and atrial fibrillation AI Shows Potential for Creating Heart Health Exercise Plans
This guideline-based simulation study evaluates the use of the DeepSeek model to generate exercise prescriptions for patients with myocardia…
A simulation study shows that AI can generate safe, guideline-based exercise plans for patients with heart conditions like heart failure and…
Functional Coronary Angiography Improves Clinical Outcomes in Multivessel STEMI Patients
Cardiology RCT
Functional Coronary Angiography Improves Clinical Outcomes in Multivessel STEMI Patients Physiology guided heart procedures show lower risk of major events
Physiology-guided revascularization significantly reduces major adverse cardiac events and improves safety profiles compared to traditional …
A large international trial shows that using functional imaging to guide heart artery procedures may lower the risk of stroke and heart atta…
High-intensity statin adherence correlates with greater LDL-C reductions and improved plaque stability post-AMI
Cardiology RCT
High-intensity statin adherence correlates with greater LDL-C reductions and improved plaque stability post-AMI High-Intensity Statins Show Better Results for Heart Patients Following Heart Attack
This randomized controlled trial sub-study of 255 patients with acute myocardial infarction evaluated high-intensity statin therapy. Adheren…
Patients who strictly followed their high-intensity statin regimen after a heart attack showed significantly better improvements in heart he…
GLP-1 receptor agonists reduce MACE (HR 0.69) and all-cause mortality (HR 0.67) in Type 2 Diabetes
Cardiology Meta-analysis
GLP-1 receptor agonists reduce MACE (HR 0.69) and all-cause mortality (HR 0.67) in Type 2 Diabetes GLP-1 medications show promise for heart health in diabetes
This meta-analysis of 37,393 patients with Type 2 Diabetes and myocardial infarction-defined populations found that GLP-1 receptor agonists …
A large review of over 37,000 patients suggests GLP-1 medications may lower heart failure risks for those with Type 2 Diabetes.
Ticagrelor monotherapy following primary PCI for STEMI shows reduced non-access site bleeding
Cardiology RCT
Ticagrelor monotherapy following primary PCI for STEMI shows reduced non-access site bleeding Trial shows ticagrelor monotherapy may reduce bleeding after heart attack
This pilot study compared ticagrelor monotherapy against ticagrelor plus aspirin in patients with STEMI after primary PCI. The trial reporte…
A pilot study suggests that using ticagrelor alone after a heart attack may reduce specific types of bleeding compared to a dual-drug approa…
Impact of Early Aspirin Withdrawal on Myocardial Infarction in Patients After PCI
Cardiology Meta-analysis
Impact of Early Aspirin Withdrawal on Myocardial Infarction in Patients After PCI Aspirin withdrawal shortly after heart procedures may increase heart attack risk
Early aspirin withdrawal within 30 days post-PCI significantly increases myocardial infarction risk, despite long-term reductions in bleedin…
Stopping aspirin within 30 days of a heart procedure may increase the risk of a heart attack in the first month.
High-dose statin preloading increases TIMI flow grade 3 and reduces all-cause mortality in STEMI
Cardiology Meta-analysis
High-dose statin preloading increases TIMI flow grade 3 and reduces all-cause mortality in STEMI High dose statins may improve outcomes for heart attack patients
This meta-analysis of 1862 patients with STEMI undergoing primary PCI indicates that high-dose statin preloading is associated with improved…
A high dose of statins before a heart procedure may improve blood flow and lower death rates for patients with a heart attack.
Ticagrelor monotherapy after primary PCI shows 3.1% MACCE versus 2.0% in DAPT group
Cardiology RCT
Ticagrelor monotherapy after primary PCI shows 3.1% MACCE versus 2.0% in DAPT group Trial shows ticagrelor alone may reduce bleeding after heart attack
This pilot randomized controlled trial of 200 STEMI patients compared ticagrelor monotherapy to ticagrelor plus aspirin (DAPT) after primary…
A new trial looks at whether using one blood thinner instead of two can reduce bleeding risks for patients after a heart attack.