AnchorMan LAA closure device non-inferior to Watchman 2.5 in patients with non-valvular atrial fibrillation
Trial shows AnchorMan device works like Watchman for stroke risk
This randomized trial of 216 patients with non-valvular atrial fibrillation at high risk of ischaemic stroke found AnchorMan non-inferior to…
A new trial shows the AnchorMan device provides similar protection against stroke compared to the Watchman device for patients with atrial f…
Left atrial appendage occlusion and NOACs reduce mortality compared with warfarin in atrial fibrillation
LAAO, low-dose NOACs beat warfarin for atrial fibrillation survival
A network meta-analysis compared left atrial appendage occlusion (LAAO), low-dose NOACs, standard-dose NOACs, and warfarin in non-valvular a…
For people with atrial fibrillation, warfarin may be the worst option for survival. New analysis finds LAAO and NOACs outperform it.
LAAC shows noninferior efficacy and reduced bleeding versus NOACs in non-valvular AF
New data shows left atrial appendage closure offers bleeding safety for some adults with atrial fibrillation
This meta-analysis of RCTs in adults with non-valvular AF found percutaneous left atrial appendage closure (LAAC) achieved noninferiority fo…
A large review of trials found that closing the heart appendage reduced bleeding compared to blood thinners. However, stroke risk trends wer…
Sex differences in outcomes after stroke in NVAF with ASCVD: a post hoc analysis
Women and Men With AFib and Clogged Arteries Share Same Stroke Risk
This post hoc analysis of an RCT included 222 patients with recent ischemic stroke or TIA, NVAF, and ASCVD. No significant sex differences w…
Women and men with AFib and clogged arteries face similar risks for stroke, heart attack, and bleeding over two years.
Machine learning models predict stroke risk in low-risk non-valvular atrial fibrillation patients using cardiac biomarkers
New ML models predict stroke risk in low-risk atrial fibrillation patients
This single-center, retrospective cohort study evaluated machine-learning models for stroke risk prediction in 82 NVAF-related stroke cases …
A new study shows machine learning models using heart markers can better predict stroke risk in patients with low-risk atrial fibrillation.
FDA Approves Xarelto (rivaroxaban) for multiple indications including stroke prevention in nonvalvular atrial fibrillation and treatment of VTE
FDA approves a new blood thinner called Xarelto for several heart and clot conditions
The FDA approved rivaroxaban (Xarelto), a factor Xa inhibitor, for multiple indications including reducing stroke risk in nonvalvular atrial…
FDA approves new blood thinner Xarelto to prevent dangerous clots in heart conditions, deep vein issues, and after major surgeries.
Research across Atrial Fibrillation
Related studies from across the Atrial Fibrillation family.
Metabolic syndrome increases risk of incident atrial fibrillation by 1.4- to 1.9-fold
Metabolic Syndrome Increases Risk of Atrial Fibrillation in Patients
This narrative review examines the association between metabolic syndrome and atrial fibrillation incidence. The authors synthesize evidence…
Metabolic syndrome is linked to a higher risk of atrial fibrillation, with high blood pressure and abdominal obesity showing the strongest c…
Conscious or deep sedation reduces procedural time in pulsed field ablation for atrial fibrillation
Comparing Sedation and General Anesthesia for Pulsed Field Ablation of Atrial Fibrillation
This meta-analysis of 10 studies involving 3,692 patients found that conscious or deep sedation (CS/DS) significantly shortened overall proc…
Doctors are finding that using light sedation instead of full general anesthesia can speed up heart procedures without hurting safety.
Yangxin Dingji plus conventional therapy reduces 6-month atrial fibrillation recurrence and improves LVEF
Yangxin Dingji Combined With Standard Care Shows Promise for Atrial Fibrillation
This meta-analysis of 872 patients evaluated Yangxin Dingji (YXDJ) as an adjunct to conventional therapy for atrial fibrillation. The study …
Adding Yangxin Dingji to standard treatment may improve symptoms and reduce the risk of heart rhythm recurrence in patients with atrial fibr…
Left atrial appendage occlusion reduces non-procedure-related bleeding but may increase ischemic stroke risk
LAAO Procedure Shows Mixed Results Compared to Oral Anticoagulants
This meta-analysis of 5,890 randomized patients evaluated left atrial appendage occlusion (LAAO) compared to oral anticoagulation for atrial…
A procedure called LAAO can reduce certain types of bleeding but may increase stroke risk compared to standard oral medications for heart pa…
Mortality Risk Factors in Atrial Fibrillation: Umbrella Review Findings
Specific risk factors linked to higher death rates in atrial fibrillation
An umbrella review found 86 of 216 risk factors significantly linked to mortality in atrial fibrillation, including several medications and …
New data identifies specific medications and health conditions that may increase the risk of death for people living with atrial fibrillatio…
Vascular closure devices reduce time to hemostasis by 5.63 minutes in atrial fibrillation ablation
Vascular closure devices speed up bleeding control in heart procedures
This meta-analysis of 30,560 patients undergoing atrial fibrillation ablation found that vascular closure devices (VCDs) significantly reduc…
New data shows that vascular closure devices help stop bleeding faster during atrial fibrillation procedures, though they do not change disc…
Empiric superior vena cava isolation reduces atrial tachyarrhythmia recurrence compared to pulmonary vein isolation alone
Adding a specific step can reduce heart rhythm issues
This meta-analysis of randomized controlled trials evaluated superior vena cava isolation (SVCI) as an adjunct to pulmonary vein isolation (…
Adding a technique called superior vena cava isolation can significantly lower the chances of heart rhythm issues returning after surgery.
Single transseptal puncture is a safe alternative to double puncture for atrial fibrillation ablation
Single Transseptal Puncture Is Safe for Atrial Fibrillation Ablation
This meta-analysis of 1811 patients evaluated single versus double transseptal puncture during atrial fibrillation ablation. The analysis fo…
A single transseptal puncture is a safe alternative to double puncture during atrial fibrillation procedures, despite taking more time to co…
Extended rhythm monitoring identifies 64% of asymptomatic atrial fibrillation in patients on BTKi therapy
BTK Inhibitors Linked to Hidden Heart Rhythm Problem in Cancer Patients
This meta-analysis of 2839 patients with hematologic malignancies treated with Bruton's tyrosine kinase inhibitors (BTKi) found an overall a…
A meta-analysis of 2,839 patients found that 14% of atrial fibrillation cases during BTK inhibitor therapy had no symptoms.
Remote ischemic preconditioning reduces postoperative atrial fibrillation in patients with specific genetic risk factors
Trial Shows Remote Ischemic Preconditioning Reduces Heart Rhythm Issues
Researchers investigated the impact of remote ischemic preconditioning on patients with a specific genetic profile undergoing coronary arter…
A new trial shows that a specific preconditioning technique may reduce the risk of heart rhythm problems after heart bypass surgery.
Intracardiac echocardiography is a safe, non-inferior alternative to transesophageal echocardiography for atrial fibrillation ablation
Intracardiac echocardiography shows safety and efficiency in atrial fibrillation procedures
This meta-analysis of 7,671 patients undergoing catheter ablation for atrial fibrillation found no significant difference between intracardi…
New data shows that intracardiac echocardiography is a safe and effective alternative to traditional imaging during atrial fibrillation hear…
Atrial fibroblast metabolic reprogramming is a candidate mechanism for multicellular atrial cardiomyopathy in atrial fibrillation
Metabolic Changes in Heart Cells May Link to Atrial Fibrillation
This narrative review evaluates atrial fibroblast metabolic reprogramming as a potential mechanism for atrial cardiomyopathy. While studies …
New research explores how changes in cell metabolism might drive heart tissue scarring and irregular heartbeats in conditions like atrial fi…
Questions about Nonvalvular Atrial Fibrillation
Is left atrial appendage occlusion better than warfarin for Nonvalvular Atrial Fibrillation mortality?
Yes, left atrial appendage occlusion (LAAO) is associated with lower all-cause mortality compared to warfarin in patients with nonvalvular atrial fibrillation, based on network meta-analyses.
Full answer →Are there sex differences in stroke outcomes for people with Nonvalvular Atrial Fibrillation?
Yes, sex differences exist: women with NVAF-related stroke tend to have worse short-term outcomes, but after adjusting for age and other factors, their long-term mortality risk may be lower.
Full answer →Does left atrial appendage closure cause less bleeding than NOACs for Nonvalvular Atrial Fibrillation?
Yes, left atrial appendage closure (LAAC) causes significantly less non-procedural bleeding than NOACs in patients with nonvalvular atrial fibrillation, based on recent trials.
Full answer →Is Xarelto approved to prevent strokes in patients with Nonvalvular Atrial Fibrillation?
Yes, Xarelto (rivaroxaban) is FDA-approved for stroke prevention in nonvalvular atrial fibrillation, based on the ROCKET-AF trial showing it is noninferior to warfarin with a favorable benefit-risk profile.
Full answer →