AnchorMan LAA closure device non-inferior to Watchman 2.5 in patients with non-valvular atrial fibrillation
Trial shows AnchorMan device works like Watchman for stroke risk
This randomized trial of 216 patients with non-valvular atrial fibrillation at high risk of ischaemic stroke found AnchorMan non-inferior to…
A new trial shows the AnchorMan device provides similar protection against stroke compared to the Watchman device for patients with atrial f…
Left atrial appendage occlusion and NOACs reduce mortality compared with warfarin in atrial fibrillation
LAAO, low-dose NOACs beat warfarin for atrial fibrillation survival
A network meta-analysis compared left atrial appendage occlusion (LAAO), low-dose NOACs, standard-dose NOACs, and warfarin in non-valvular a…
For people with atrial fibrillation, warfarin may be the worst option for survival. New analysis finds LAAO and NOACs outperform it.
LAAC shows noninferior efficacy and reduced bleeding versus NOACs in non-valvular AF
New data shows left atrial appendage closure offers bleeding safety for some adults with atrial fibrillation
This meta-analysis of RCTs in adults with non-valvular AF found percutaneous left atrial appendage closure (LAAC) achieved noninferiority fo…
A large review of trials found that closing the heart appendage reduced bleeding compared to blood thinners. However, stroke risk trends wer…
Sex differences in outcomes after stroke in NVAF with ASCVD: a post hoc analysis
Women and Men With AFib and Clogged Arteries Share Same Stroke Risk
This post hoc analysis of an RCT included 222 patients with recent ischemic stroke or TIA, NVAF, and ASCVD. No significant sex differences w…
Women and men with AFib and clogged arteries face similar risks for stroke, heart attack, and bleeding over two years.
Machine learning models predict stroke risk in low-risk non-valvular atrial fibrillation patients using cardiac biomarkers
New ML models predict stroke risk in low-risk atrial fibrillation patients
This single-center, retrospective cohort study evaluated machine-learning models for stroke risk prediction in 82 NVAF-related stroke cases …
A new study shows machine learning models using heart markers can better predict stroke risk in patients with low-risk atrial fibrillation.
FDA Approves Xarelto (rivaroxaban) for multiple indications including stroke prevention in nonvalvular atrial fibrillation and treatment of VTE
FDA approves a new blood thinner called Xarelto for several heart and clot conditions
The FDA approved rivaroxaban (Xarelto), a factor Xa inhibitor, for multiple indications including reducing stroke risk in nonvalvular atrial…
FDA approves new blood thinner Xarelto to prevent dangerous clots in heart conditions, deep vein issues, and after major surgeries.
Research across Atrial Fibrillation
Related studies from across the Atrial Fibrillation family.
Thoracic Radiotherapy Linked to 7.6% Pooled Incidence of Reported Atrial Fibrillation
Thoracic radiation for cancer may increase risk of heart rhythm issues
This meta-analysis of 9 cohort-level estimates examines reported atrial fibrillation after thoracic radiotherapy in adults with thoracic mal…
New data shows that patients receiving radiation for chest cancers may face a higher risk of developing atrial fibrillation, a common heart …
Composite lipid and metabolic indices show more consistent associations with atrial fibrillation recurrence than individual measures
Lipid Profiles May Reflect Metabolic Burden in Atrial Fibrillation
This narrative review examines the relationship between circulating lipid profiles and atrial fibrillation risk or post-ablation recurrence.…
New research suggests that lipid levels in the blood may reflect overall metabolic health rather than acting as direct causes of heart rhyth…
Pulsed-field ablation shows shorter ablation times and lower phrenic nerve palsy than cryoballoon ablation
Pulsed-field Ablation Shows Faster Times for Atrial Fibrillation Treatment
This meta-analysis of 2024 patients with atrial fibrillation undergoing pulmonary vein isolation compares pulsed-field ablation (PFA) to cry…
A new analysis suggests pulsed-field ablation may offer faster procedure times and lower nerve damage risks for patients with atrial fibrill…
Clinical risk factors including smoking and sleep apnea increase arrhythmia recurrence after atrial fibrillation ablation
Clinical risk factors linked to higher atrial fibrillation recurrence rates
This meta-analysis examined various clinical risk factors and their impact on arrhythmia recurrence in patients undergoing catheter ablation…
Specific health conditions like sleep apnea and gum disease are linked to a higher risk of heart rhythm issues returning after surgery.
Early oral anticoagulants show no significant difference in stroke risk compared to late initiation
Early blood thinners show no extra risks for stroke patients
This meta-analysis of 6522 adults with atrial fibrillation and recent ischemic stroke found no significant difference in recurrent ischemic …
Starting blood thinners soon after a stroke does not increase the risk of bleeding or death compared to waiting.
DOACs reduce device-related thrombosis and bleeding risk compared to DAPT after left atrial appendage closure
DOACs Show Lower Risk of Blood Clots After Heart Procedure
This meta-analysis of 704 patients with atrial fibrillation undergoing percutaneous left atrial appendage closure found that DOACs significa…
Patients with atrial fibrillation may have a lower risk of blood clots and bleeding when using DOACs after a specific heart procedure.
DOACs reduce stroke, mortality, and major bleeding risk compared to vitamin K antagonists in hemodialysis
DOACs Show Lower Stroke and Bleeding Risk in Dialysis Patients
This meta-analysis evaluated the efficacy and safety of direct oral anticoagulants (DOACs) compared to vitamin K antagonists in patients wit…
Patients with atrial fibrillation on hemodialysis may have lower risks of stroke and major bleeding when using DOACs instead of vitamin K an…
Digital recruitment strategy yielded 1,406 registrations from 1,319 potential individuals with atrial fibrillation
Digital Ads Help Recruit Patients for Atrial Fibrillation Trials
This observational feasibility study evaluated digital recruitment strategies using online advertisements and a pre-screening website for at…
New data shows digital advertising can help find more diverse participants for atrial fibrillation clinical trials, though some gaps remain.
Double-chambered left ventricle in adulthood with severe mitral regurgitation and refractory heart failure
Complex heart structure can cause severe heart failure in adults
This case report describes a 50-year-old man with longstanding atrial fibrillation and heart failure with reduced ejection fraction, found t…
A man with a rare double-chambered heart and chronic irregular heartbeat showed that complex anatomy can lead to severe heart failure.
Adding antiplatelet therapy to anticoagulation does not cut stroke risk but raises major bleeding
Combined Anticoagulant and Antiplatelet Therapy Increases Bleeding Risk
This meta-analysis of 14,884 patients with recent ischemic stroke, nonvalvular atrial fibrillation, and large artery atherosclerosis found t…
Combining two types of blood thinners may increase bleeding risks without reducing the chance of a second stroke in patients with certain he…
Postoperative atrial fibrillation increases long-term thromboembolic risk following CABG and isolated valve surgery
Atrial Fibrillation After Heart Surgery Linked to Higher Blood Clot Risk
This meta-analysis of observational studies indicates that postoperative atrial fibrillation (POAF) is associated with increased long-term t…
New analysis suggests that patients who develop atrial fibrillation after heart surgery face a higher risk of long-term blood clots.
DOACs associated with lower risks of recurrent ICH, ischemic stroke, and mortality in atrial fibrillation
Trial Shows Direct Oral Anticoagulants Reduce Risks for Atrial Fibrillation
This meta-analysis evaluates the efficacy of direct oral anticoagulants (DOACs) compared to vitamin K antagonists (VKAs) in patients with at…
New data suggests that direct oral anticoagulants may lower the risk of stroke and bleeding for patients with atrial fibrillation.
Questions about Nonvalvular Atrial Fibrillation
Is left atrial appendage occlusion better than warfarin for Nonvalvular Atrial Fibrillation mortality?
Yes, left atrial appendage occlusion (LAAO) is associated with lower all-cause mortality compared to warfarin in patients with nonvalvular atrial fibrillation, based on network meta-analyses.
Full answer →Are there sex differences in stroke outcomes for people with Nonvalvular Atrial Fibrillation?
Yes, sex differences exist: women with NVAF-related stroke tend to have worse short-term outcomes, but after adjusting for age and other factors, their long-term mortality risk may be lower.
Full answer →Does left atrial appendage closure cause less bleeding than NOACs for Nonvalvular Atrial Fibrillation?
Yes, left atrial appendage closure (LAAC) causes significantly less non-procedural bleeding than NOACs in patients with nonvalvular atrial fibrillation, based on recent trials.
Full answer →Is Xarelto approved to prevent strokes in patients with Nonvalvular Atrial Fibrillation?
Yes, Xarelto (rivaroxaban) is FDA-approved for stroke prevention in nonvalvular atrial fibrillation, based on the ROCKET-AF trial showing it is noninferior to warfarin with a favorable benefit-risk profile.
Full answer →