Left atrial appendage occlusion and NOACs reduce mortality compared with warfarin in atrial fibrillation
LAAO, low-dose NOACs beat warfarin for atrial fibrillation survival
A network meta-analysis compared left atrial appendage occlusion (LAAO), low-dose NOACs, standard-dose NOACs, and warfarin in non-valvular a…
For people with atrial fibrillation, warfarin may be the worst option for survival. New analysis finds LAAO and NOACs outperform it.
Sex differences in outcomes after stroke in NVAF with ASCVD: a post hoc analysis
Women and Men With AFib and Clogged Arteries Share Same Stroke Risk
This post hoc analysis of an RCT included 222 patients with recent ischemic stroke or TIA, NVAF, and ASCVD. No significant sex differences w…
Women and men with AFib and clogged arteries face similar risks for stroke, heart attack, and bleeding over two years.
Machine learning models predict stroke risk in low-risk non-valvular atrial fibrillation patients using cardiac biomarkers
New ML models predict stroke risk in low-risk atrial fibrillation patients
This single-center, retrospective cohort study evaluated machine-learning models for stroke risk prediction in 82 NVAF-related stroke cases …
A new study shows machine learning models using heart markers can better predict stroke risk in patients with low-risk atrial fibrillation.
FDA Approves Xarelto (rivaroxaban) for multiple indications including stroke prevention in nonvalvular atrial fibrillation and treatment of VTE
FDA approves a new blood thinner called Xarelto for several heart and clot conditions
The FDA approved rivaroxaban (Xarelto), a factor Xa inhibitor, for multiple indications including reducing stroke risk in nonvalvular atrial…
FDA approves new blood thinner Xarelto to prevent dangerous clots in heart conditions, deep vein issues, and after major surgeries.
Research across Atrial Fibrillation
Related studies from across the Atrial Fibrillation family.
SGLT2 inhibitors provide robust prognostic benefits in heart failure with inconsistent results in post-myocardial infarction settings
SGLT2 inhibitors show promise for heart failure and diabetes
This narrative review examines the cardiovascular and metabolic effects of SGLT2 inhibitors, specifically empagliflozin and dapagliflozin. T…
New evidence shows how SGLT2 inhibitors may protect the heart and manage risks for patients with type 2 diabetes and heart failure.
Incidental arrhythmia findings on ambulatory ECG vary widely in adults without prior atrial fibrillation
Hidden heart rhythm problems found in up to 96% of adults
This systematic review and meta-analysis of 136,344 community-based adults without prior atrial fibrillation found that the prevalence of in…
A review of 136,344 adults found hidden heart rhythm issues in up to 96% of people without known atrial fibrillation.
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients
Renal denervation may help resistant hypertension patients with heart issues
This systematic review and meta-analysis evaluated renal denervation in patients with resistant hypertension. The pooled analysis included 8…
A meta-analysis suggests renal denervation improves heart and sleep markers in patients with resistant hypertension, though larger trials ar…
Hypertension history associates with 2.22-fold higher cognitive impairment risk in AF patients
High blood pressure history doubles dementia risk in atrial fibrillation patients
This systematic review and meta-analysis of observational studies found that a history of hypertension is associated with an increased risk …
A history of high blood pressure is linked to a much higher risk of cognitive impairment in people with atrial fibrillation, according to a …
Pulsed-field ablation shows no significant AKI difference versus radiofrequency ablation in AF
Pulsed-field ablation shows similar kidney risk as radiofrequency ablation
This systematic review and meta-analysis of 3,843 patients found no significant difference in acute kidney injury (AKI) between pulsed-field…
A large review found no major difference in kidney injury risk between two heart rhythm treatments, though one method showed slightly higher…
Discontinuing oral anticoagulation after AF ablation reduces bleeding without increasing thromboembolic risk
Stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger
This systematic review and meta-analysis evaluated patients who stopped versus continued oral anticoagulation following atrial fibrillation …
A massive analysis shows stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger for many patient…
Narrative review on atrial fibrillation and depression highlights bidirectional links and integrated care needs
Depression and heart rhythm problems may worsen each other
This narrative review synthesizes evidence on the bidirectional relationship between atrial fibrillation and depression. It suggests depress…
A new review suggests depression and atrial fibrillation can fuel each other, making it vital to screen for both conditions together.
LAAC shows noninferior efficacy and reduced bleeding versus NOACs in non-valvular AF
New data shows left atrial appendage closure offers bleeding safety for some adults with atrial fibrillation
This meta-analysis of RCTs in adults with non-valvular AF found percutaneous left atrial appendage closure (LAAC) achieved noninferiority fo…
A large review of trials found that closing the heart appendage reduced bleeding compared to blood thinners. However, stroke risk trends wer…
Edoxaban trough concentration and PT predict major bleeding in very old AF patients
Blood thinner levels linked to bleeding in very old patients
This post hoc analysis of the ELDERCARE-AF RCT included 427 very old Japanese patients with atrial fibrillation and high bleeding risk. High…
Higher edoxaban levels in the blood may increase bleeding risk in patients 80 and older with atrial fibrillation.
Review links metabolic syndrome to 1.5 to 2 times higher atrial fibrillation risk
Metabolic syndrome raises atrial fibrillation risk by 1.5 to 2 times
This narrative review examines the association between metabolic syndrome and atrial fibrillation. The authors synthesize evidence suggestin…
Metabolic syndrome increases the risk of developing atrial fibrillation by 1.5 to 2 times, a finding that could help doctors target preventi…
Editorial argues emergency physicians are key to AF heart teams
Emergency doctors key to atrial fibrillation care, editorial says
This editorial argues that emergency physicians are indispensable members of atrial fibrillation heart teams. They enhance integration of ac…
An editorial argues emergency physicians should be core members of AF heart teams to improve care coordination and outcomes.
Routine prophylactic left atrial appendage closure did not significantly reduce the incidence of the primary composite endpoint
Routine valve closure did not significantly reduce stroke risk in heart surgery patients
In a randomized trial involving 2118 patients undergoing valve repair or replacement, surgical left atrial appendage occlusion failed to low…
A major surgery trial found that closing a heart chamber did not lower stroke risk compared to standard care for patients getting valve repa…