Deep Learning algorithms demonstrate potential for diagnosing oral potentially malignant disorders and squamous cell carcinoma
Artificial Intelligence Shows Potential for Detecting Oral Cancer
This meta-analysis evaluated the diagnostic accuracy of deep learning models using white light digital photographs to identify oral malignan…
New research shows that deep learning tools can help identify oral cancer and precancerous conditions using simple digital photos.
PD-L1 expression shows potential utility in predicting malignant transformation risk in oral potentially malignant disorders
PD-L1 expression may help identify risk in oral pre-cancer
This meta-analysis of 613 patients with oral potentially malignant disorders (OPMDs) found a malignant transformation rate of 21.04% (129 ou…
A review of patient data suggests that checking for specific immune markers could help doctors identify which oral tissue changes are more l…
Molecular markers may improve risk assessment in oral potentially malignant disorders
Molecular tools may improve risk assessment for oral lesions
This narrative review examines the limitations of conventional histopathological grading for oral potentially malignant disorders (OPMDs) an…
A review suggests molecular methods could better assess risk for oral potentially malignant disorders where standard grading is unreliable.
Meta-analysis identifies transcriptomic and immune shifts in oral potentially malignant disorders
Your Mouth's Immune Signals Predict Oral Cancer Risk Earlier
This meta-analysis of five datasets examines transcriptomic patterns and signaling processes across stages of oral potentially malignant dis…
• Immune cell patterns flag dangerous mouth lesions before cancer develops • Helps people with persistent white or red mouth sores • Still n…
Meta-analysis of VELscope diagnostic accuracy for oral potentially malignant disorders
Meta-analysis reviews VELscope device for detecting oral potentially malignant disorders
This meta-analysis of 24 studies evaluated VELscope for detecting oral potentially malignant disorders.
The VELscope screening tool catches most oral cancer cases but often flags healthy mouths as risky, causing unnecessary worry and extra test…
Research across Cancer
Related studies from across the Cancer family.
Postoperative conventional fractionation radiotherapy is more cost-effective than preoperative accelerated fractionation for oral cavity cancer
Postoperative radiation shows better quality of life for oral cancer
This randomized controlled trial of 240 patients with oral cavity cancer found that preoperative accelerated fractionation radiotherapy was …
Patients with oral cavity cancer may experience fewer symptoms and better quality of life with standard postoperative radiation.
Meta-analysis Evaluating Occupational Hexavalent Chromium Exposure and Specific Malignancy Risks
Occupational Chromium Exposure Linked to Bladder Cancer Mortality
A meta-analysis of 29 publications examined how occupational hexavalent chromium exposure impacts various cancer types in human populations.
A review of 29 publications found that while most cancers showed no link, bladder cancer mortality was associated with hexavalent chromium e…
Mirtazapine and olanzapine reduce anxiety and depression scores in oral cavity cancer patients
Two Common Pills Ease Cancer Anxiety and Depression
This randomized controlled trial included 144 patients with oral cavity cancer.
Two well-known antidepressants significantly eased anxiety and depression in oral cancer patients, with mirtazapine showing a slight edge.
Oral and pharyngeal cancer incidence increased in US population from 2007 to 2016
U.S. study finds rising rates of oral and throat cancers over a decade
An observational study of the US population from 2007 to 2016 found increasing incidence of combined oral cavity and pharyngeal cancers.
U.S. cancer rates for the mouth and throat rose between 2007 and 2016, possibly linked to more cases caused by HPV.
Questions about oral potentially malignant disorders
Can molecular markers improve over traditional grading for oral potentially malignant disorders?
Molecular markers may improve risk assessment for oral potentially malignant disorders (OPMD) because traditional grading based on tissue appearance can be unreliable due to the biological variety of these lesions.
Full answer →Are molecular markers better for assessing risk in oral potentially malignant disorders?
Molecular markers show promise for improving risk assessment in oral potentially malignant disorders, but they are not yet proven better than standard histopathology and need more validation.
Full answer →