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Allergy & Immunology
Sys. Review
Extracellular vesicle signalling may participate in postoperative neurocognitive disorder progression in older surgical patients
Scientists explore how stress signals might worsen brain recovery after surgery
This review examines extracellular vesicle signalling as a potential mechanism in perioperative neurocognitive disorders among older and vul…
Current evidence suggests multiple factors drive brain issues after surgery, but exactly how stress signals cause lasting problems remains u…
Frontiers
Jun 2, 2026
Psychiatry
RCT
Parecoxib reduces postoperative anxiety but not cognitive decline in pancreaticoduodenectomy patients
Pain Drug Cuts Anxiety After Major Surgery
This randomized controlled trial of 80 patients undergoing laparoscopic pancreaticoduodenectomy evaluated intravenous parecoxib versus salin…
A common pain drug called parecoxib significantly lowers anxiety and may reduce mental fog for patients recovering from major pancreatic sur…
NEJM
Apr 19, 2026