Co-administration of CD19 and CD22 CAR-T therapy in pediatric relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
Years Later, These Kids With Tough Leukemia Are Still in Remission
This retrospective subanalysis evaluated long-term outcomes in pediatric patients with relapsed/refractory Philadelphia chromosome-positive …
Pairing two reprogrammed immune cell therapies gave most kids with an aggressive form of leukemia long-term remission — without a single tre…
In children with Ph+ ALL, TKI-based therapy reduced HSCT use while maintaining comparable outcomes versus Ph+ALL04.
Reduced transplant use showed similar outcomes in children with Philadelphia chromosome-positive leukemia
This single-arm Phase 2 trial evaluated chemotherapy with tyrosine kinase inhibitors (TKIs) guided by minimal residual disease in 41 eligibl…
Children with a specific leukemia type achieved similar survival rates without stem cell transplants, offering a less intensive treatment op…