Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Conditions › Prader–Willi syndrome

Prader–Willi syndrome

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Prader–Willi syndrome

14 trials tracked for Prader–Willi syndrome: 4 in phase 3 or 4 and 3 with published results. The most-cited published study has 49 citations.

14Trials tracked
4Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 3 4 Phase 2 8 Other / NA 2
  1. Phase 3 A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome Completed · 49 cited
  2. Phase 3 Phase 3 Study of Intranasal Carbetocin (LV-101) in Patients With Prader-Willi Syndrome Completed · 48 cited
  3. Phase 3 Study of the Efficacy and Safety of Somatropin in Japanese Participants With PWS Completed
  4. Phase 3 Growth Hormone Use in Adults With Prader-Willi Syndrome Completed
  5. Phase 2 Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS Infants Completed
  6. Phase 2 Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome Completed
Show 8 more trials
  1. Phase 2 A Study of GLWL-01 in Patients With Prader-Willi Syndrome Completed
  2. Phase 2 A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension Completed
  3. Phase 2 Understanding the Role of Gut Microbiota in Hyperphagia in Prader-Willi Syndrome Completed
  4. Phase 2 Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome Completed
  5. Phase 2 Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome Completed
  6. Phase 2 Intranasal Oxytocin for Infants With Prader-Willi Syndrome Completed
  7. N/A Effects of Exenatide on Overweight Adolescents With Prader-Willi Syndrome Completed
  8. N/A Pilot Study of Startle-response Test to Assess Transcranial Direct Current Stimulation-induced Modulation of Hyperphagia in Prader-Willi Syndrome Completed

Showing the 14 most-cited and recently-updated of 14 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
MCH1 Receptor Antagonist RGH-706 Shows Weight Loss in Preclinical and Early Clinical Study
Diabetes & Endocrinology Phase I
MCH1 Receptor Antagonist RGH-706 Shows Weight Loss in Preclinical and Early Clinical Study New Drug Targets Hunger Brain Signals to Help Shed Pounds
A preclinical and phase I/II study evaluated the MCH1 receptor antagonist RGH-706 for obesity and Prader-Willi Syndrome.
Scientists found a new medicine that may help people lose weight by turning off hunger signals.
Apr 24, 2026
Endocrine-informed monitoring framework for scoliosis in children with Prader-Willi syndrome
Diabetes & Endocrinology Cohort
Endocrine-informed monitoring framework for scoliosis in children with Prader-Willi syndrome Why Growth Hormone Might Hurt Your Spine
This narrative review evaluates an endocrine-informed monitoring framework for scoliosis in children and adolescents with Prader-Willi syndr…
Doctors now know to watch growth hormone levels and puberty stages to stop bad spinal curves before they get worse.
Frontiers Apr 13, 2026