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Primary Peritoneal Cancer

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Primary Peritoneal Cancer

22 trials tracked for Primary Peritoneal Cancer: 2 in phase 3 or 4 and 1 with published results. The most-cited published study has 20 citations.

22Trials tracked
2Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 2 Phase 2 16 Phase 1 2 Other / NA 2
  1. Phase 3 A Study of the Efficacy and Safety of Bevacizumab in Chinese Women With Newly Diagnosed, Previously Untreated Stage III or Stage IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Completed · 20 cited
  2. Phase 3 Saracatinib and Paclitaxel in Platinum-resistant Ovarian Cancer Completed
  3. Phase 2 A Study LY2228820 for Recurrent Ovarian Cancer Completed
  4. Phase 2 Japan Phase 2 Study of Niraparib in Participants With Advanced, Relapsed Ovarian Cancer Completed
  5. Phase 2 Allogeneic Natural Killer (NK) Cells for Ovarian, Fallopian Tube, Peritoneal and Metastatic Breast Cancer Completed
  6. Phase 2 Gleevec and Gemzar in Patients With Epithelial Ovarian Cancer Completed
Show 16 more trials
  1. Phase 2 Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations Completed
  2. Phase 2 Neoadjuvant Therapy for Ovarian Cancer Completed
  3. Phase 2 Hu3S193 in Treating Women With Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer Completed
  4. Phase 2 Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab Completed
  5. Phase 2 Japan Phase 2 Study of Niraparib (Maintenance Therapy) in Participants With Relapsed Ovarian Cancer Completed
  6. Phase 2 Avastin +/- Erlotinib Consolidation Chemotherapy After Carboplatin, Paclitaxel, and Avastin (CTA) Induction Therapy for Advanced Ovarian, Fallopian Tube, Primary Peritoneal Cancer & Papillary Serous or Clear Cell Mullerian Tumors Completed
  7. Phase 2 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab, Carboplatin, Pegylated Liposomal Doxorubicin, Pembrolizumab, or Bevacizumab + Carboplatin in Participants With Folate Receptor Alpha (FRα) Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal, or Fallopian Tube Cancer Completed
  8. Phase 2 VTX-2337 and Pegylated Liposomal Doxorubicin (PLD) in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer Completed
  9. Phase 2 A Study of Chemotherapy Treatment for Patients With Ovarian Cancer Completed
  10. Phase 2 Trial of Pemetrexed and Carboplatin in Patients With Recurrent Ovarian or Primary Peritoneal Cancer Completed
  11. Phase 2 Phase II ABT-888 With Cyclophosphamide Completed
  12. Phase 2 Sorafenib and Bevacizumab to Treat Ovarian, Fallopian and Peritoneal Cancer Completed
  13. Phase 1 Phase 1 Study of NY-ESO-1 Overlapping Peptides in Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Completed
  14. Phase 1 Neoadjuvant Chemotherapy IV Carboplatin With Weekly Paclitaxel \Bevacizumab for Primary Ovarian Completed
  15. N/A Outcomes in Ovarian Cancer and Fallopian Tube Cancer Patients Using Complementary Alternative Medicine Completed
  16. N/A Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study Completed

Showing the 22 most-cited and recently-updated of 22 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Primary Peritoneal Cancer: what the trials found

Paclitaxel treatment in patients with primary peritoneal cancer is associated with statistically significant improvements in progression-free survival (PFS) 1. Clinical observations also indicate that Paclitaxel is associated with improvements in patient-reported abdominal pain (ranging from 31.3% to 48.4%) and bloating (ranging from 26.1% to 47.4%) 1. However, other trials evaluating Paclitaxel did not find a statistically significant difference in 6-month progression-free survival rates 2 or overall survival 2.

Carboplatin has been evaluated in clinical settings for this condition 20, and its administration was associated with specific quality of life (QOL) scores 5.

Niraparib was evaluated in a Phase 2 trial, where 17 participants experienced Grade 3 or higher treatment-emergent adverse events (TEAEs) 7. In a separate trial, 14 participants experienced Grade 3 or higher TEAEs, and 6 participants experienced Grade 3 or 4 thrombocytopenia within 30 days of initial administration 8.

Bevacizumab has been established in clinical trials for this condition [14, 15].

Recent results — preliminary, needs further review

  • Rucaparib was evaluated in a recent study where the average dose received per 12 hours was 545.5 and 513.5 21.

For the clinician treating this condition

  • Paclitaxel is associated with statistically significant improvements in progression-free survival and may correlate with improvements in patient-reported symptoms like abdominal pain and bloating 1.
  • Niraparib is associated with specific safety profiles, including Grade 3 or higher TEAEs and instances of Grade 3 or 4 thrombocytopenia [7, 8].
  • Carboplatin and Bevacizumab are established interventions in the treatment landscape for primary peritoneal cancer [14, 15, 20].

AI synthesis of 7 cited trials, updated Sep 19, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.