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Home › Conditions › Radiation dermatitis

Radiation dermatitis

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Radiation dermatitis

6 trials tracked for Radiation dermatitis: 1 in phase 3 or 4 and 1 with published results. The most-cited published study has 38 citations.

6Trials tracked
1Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 1 Phase 1 1 Other / NA 4
  1. Phase 3 Bacterial Decolonization to Prevent Radiation Dermatitis Completed · 38 cited
  2. Phase 1 Silverlon to Reduce Radiation Dermatitis Completed
  3. N/A KeraStat(R) Cream for Radiation Dermatitis Completed
  4. N/A Low Level Laser Therapy for Radiation Induced Dermatitis in H & N Squamous Cell Carcinoma Completed
  5. N/A MediHoney for Radiation Dermatitis Completed
  6. N/A Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy Completed

Showing the 6 most-cited and recently-updated of 6 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Radiation dermatitis: what the trials found

Chlorhexidine gluconate solution has been shown to significantly reduce the incidence of high-grade radiation dermatitis compared to the control group (0 vs. 9; p=0.004) 1.

While chlorhexidine gluconate was effective in reducing high-grade cases, it did not result in a statistically significant improvement in Quality of Life scores as measured by the Skindex-16 Dermatological Survey (p=0.20) 1.

Recent results — preliminary, needs further review

  • Silverlon showed varying outcomes across RTOG toxicity scores in a small cohort (N=31) 2.
  • The THOR Laser System for Low Level Laser Therapy (LLLT) was evaluated with 9 instances of Grade 3 or higher adverse events reported 3.
  • KeraStat Cream was evaluated regarding the number of participants with Grade 2+ radiation dermatitis and Dermatology Life Quality Index scores, though results were not statistically significant [4, 5].
  • Hydrophor (Group A) was investigated in a study involving 34 participants 6.

For the clinician treating this condition

  • Chlorhexidine gluconate is an effective intervention for preventing high-grade radiation dermatitis 1.
  • Clinical use of chlorhexidine gluconate does not currently show a statistically significant impact on patient-reported quality of life scores via Skindex-16 1.

AI synthesis of 4 cited trials, updated Jun 29, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
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