Narrative review examines synthetic circRNA therapeutics versus mRNA and saRNA in oncology and rare diseases.
A Ring-Shaped Medicine Could Last Longer Than Anything Before It
This narrative review evaluates preclinical and early translational evidence regarding synthetic (exogenous) circRNA therapeutics compared t…
A ring-shaped RNA molecule could last longer inside the body than standard medicines, potentially helping treat cancer and rare diseases.
Phenotype database PAVS shows utility for gene prioritization in rare disease cases
New database helps prioritize genes for rare disease diagnosis in Saudi Arabian patients
An observational database evaluation study assessed PAVS, a curated database integrating phenotype-associated variants from Saudi Arabian ra…
A new database called PAVS helps doctors prioritize genes for rare diseases in Saudi patients by combining genetic data with detailed sympto…