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Home › Conditions › thyroid eye disease

Thyroid eye disease

Part of Graves' disease

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for thyroid eye disease

5 trials tracked for thyroid eye disease: 3 in phase 3 or 4 and 2 with published results. The most-cited published study has 694 citations.

5Trials tracked
3Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 1 Phase 3 2 Phase 2 1 Other / NA 1
  1. Phase 3 Treatment of Graves' Orbitopathy (Thyroid Eye Disease) to Reduce Proptosis With Teprotumumab Infusions in a Randomized, Placebo-Controlled, Clinical Study Completed · 694 cited
  2. Phase 3 Treatment of Graves' Orbitopathy to Reduce Proptosis With Teprotumumab Infusions in an Open-Label Clinical Extension Study Completed · 26 cited
  3. Phase 4 A Study Evaluating TEPEZZA® Treatment in Patients With Chronic (Inactive) Thyroid Eye Disease Completed
  4. Phase 2 A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease Completed
  5. N/A Twenty-four Hour Intraocular Pressure Patterns in Patients With Uncontrolled Thyroid Eye Disease Completed

Showing the 5 most-cited and recently-updated of 5 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis reports elevated IL-6 and IL-17 in thyroid eye disease patients
Diabetes & Endocrinology Meta-analysis
Meta-analysis reports elevated IL-6 and IL-17 in thyroid eye disease patients New Clues in Your Tears Could Change Thyroid Eye Disease Care
This meta-analysis of observational studies found that serum or tear levels of IL-6 and IL-17 were significantly higher in patients with thy…
Two inflammatory markers found in blood and tears are significantly higher in people with thyroid eye disease, offering new clues for faster…
Frontiers May 8, 2026
Intravenous tocilizumab improves clinical activity in moderate-to-severe thyroid eye disease patients
Diabetes & Endocrinology Cohort
Intravenous tocilizumab improves clinical activity in moderate-to-severe thyroid eye disease patients Doctors spot four signs that predict which eye disease patients will heal fastest
This retrospective cohort study evaluated intravenous tocilizumab in 234 patients with moderate-to-severe thyroid eye disease at Beijing Ton…
A new study reveals four simple blood tests that tell doctors if a specific eye drug will work for you soon.
Frontiers Apr 27, 2026

Research across Graves' disease

Related studies from across the Graves' disease family.

Baseline vitamin D deficiency occurred in 73.08% of TAO patients receiving IVGC therapy with calcium supplementation
Allergy & Immunology Cohort
Baseline vitamin D deficiency occurred in 73.08% of TAO patients receiving IVGC therapy with calcium supplementation Simple Blood Test Could Predict Thyroid Eye Treatment Success
This retrospective cohort study evaluated 52 thyroid-associated ophthalmopathy patients treated with intravenous glucocorticoids and standar…
Checking vitamin D levels could help doctors choose the best treatment for thyroid eye disease.
Frontiers Apr 21, 2026