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Trigeminal Neuralgia

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Trigeminal Neuralgia

3 trials tracked for Trigeminal Neuralgia: 1 in phase 3 or 4.

3Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 2 1 Other / NA 1
  1. Phase 4 Anti-CGRP for Inflammation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia Completed
  2. Phase 2 Efficacy of Guanfacine and Lidocaine Combination in Trigeminal Nerve Block for Pain Management in Trigeminal Neuropathy Completed
  3. N/A Research Study to Test Safety and Effectiveness of Investigational Drug in Patients With Trigeminal Neuralgia Completed

Showing the 3 most-cited and recently-updated of 3 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Questions about Trigeminal Neuralgia

How effective is percutaneous balloon compression for multiple sclerosis trigeminal neuralgia patients?

Percutaneous balloon compression offers strong initial pain relief for multiple sclerosis-related trigeminal neuralgia, but pain often returns within a year, and the procedure carries a risk of facial numbness and chewing weakness.

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Are there specific prediction models for trigeminal neuralgia recurrence in 4,291 patients?

Yes, a 2025 meta-analysis analyzed 4,291 patients to create prediction models for trigeminal neuralgia recurrence, finding an average accuracy of 0.86.

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What is the success rate for microvascular decompression in multiple sclerosis trigeminal neuralgia?

Microvascular decompression (MVD) shows a 30.2% long-term success rate for pain relief in multiple sclerosis-related trigeminal neuralgia, though some single-center studies report higher initial success.

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