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Home › Conditions › Vaginal Atrophy

Vaginal Atrophy

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Vaginal Atrophy

12 trials tracked for Vaginal Atrophy: 9 in phase 3 or 4 and 6 with published results. The most-cited published study has 244 citations.

12Trials tracked
9Phase 3 & 4
0Recruiting
6With published results
Phase distribution
Phase 4 3 Phase 3 6 Phase 2 2 Other / NA 1
  1. Phase 3 Intravaginal Prasterone (DHEA) Against Vulvovaginal Atrophy Associated With Menopause Completed · 244 cited
  2. Phase 3 Topical DHEA Against Vaginal Atrophy Completed · 190 cited
  3. Phase 3 DHEA Against Vaginal Atrophy - 3-Month Efficacy Study Completed · 104 cited
  4. Phase 3 Dehydroepiandrosterone (DHEA) Against Vaginal Atrophy Completed · 90 cited
  5. Phase 3 DHEA Against Vaginal Atrophy - Safety Study of 12 Months Completed · 90 cited
  6. Phase 3 Study to Determine Efficacy & Safety of a Low Concentration Estriol (0.005%) in Postmenopausal Vaginal Atrophy. Completed · 76 cited
Show 6 more trials
  1. Phase 4 Vaginal Estrogen on Postpartum Atrophy, Perineal Pain, and Sexual Function Completed
  2. Phase 4 Investigation of Microbiomes of Postmenopausal Women Looking for Outcomes and Response to Estrogen Therapy Completed
  3. Phase 4 Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial Completed
  4. Phase 2 A Clinical Trial to Assess the Safety of 0.005 % Estriol Vaginal Gel in Hormone Receptor-Positive Postmenopausal Women With Early Stage Breast Cancer in Treatment With Aromatase Inhibitor in the Adjuvant Setting Completed
  5. Phase 2 Study Evaluating the Efficacy and Safety of Three Formulations of Ultra-low Dose Estriol Vaginal Gel (0.005%, 0.002%, 0.0008% Estriol Vaginal Gel) for the Treatment of Vaginal Dryness in Postmenopausal Women With Vulvovaginal Atrophy Completed
  6. N/A Radiofrequency and Hybrid Fractional Laser for Vaginal Rejuvenation Completed

Showing the 12 most-cited and recently-updated of 12 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Non-hormonal vaginal moisturizer improves vaginal health indices in postmenopausal breast cancer survivors
OB/GYN & Women's Health RCT
Non-hormonal vaginal moisturizer improves vaginal health indices in postmenopausal breast cancer survivors Can a simple moisturizer help breast cancer survivors with vaginal discomfort?
An open-label randomized trial in 100 postmenopausal breast cancer survivors with vaginal symptoms found that a non-hormonal vaginal moistur…
A simple non-hormonal moisturizer improved vaginal health scores and tissue pH in breast cancer survivors who finished treatment, offering r…
Apr 8, 2026