Research across Asthma
Related studies from across the Asthma family.
Biologics provide effective and long-lasting disease control for chronic rhinosinusitis with nasal polyps
Biologics May Help Chronic Sinusitis With Nasal Polyps
This narrative review examines the efficacy of biologics, including dupilumab, mepolizumab, omalizumab, and tezepelumab, for patients with c…
A new review suggests biologic drugs may improve sinus symptoms, smell, and asthma in people with nasal polyps.
Epigenetic mechanisms provide a molecular interface between genetic susceptibility and immune dysregulation in asthma
Epigenetic markers could help identify specific types of asthma
This mini review explores how epigenetic mechanisms, including DNA methylation and histone modifications, link environmental exposures to im…
New research explores how chemical changes to DNA could help doctors identify specific types of asthma and tailor treatments to individual p…
Macrophage metabolic reprogramming and polarization may offer therapeutic targets for chronic airway inflammatory diseases
Metabolic Reprogramming May Offer New Path for Airway Inflammation
This systematic review examines the role of macrophage polarization and metabolic reprogramming in chronic upper and lower airway inflammato…
New research suggests that changing how certain immune cells process energy could offer a way to treat asthma and chronic sinus infections.
Depemokimab shows no significant difference from other biologics in reducing severe asthma exacerbations
Depemokimab Shows Similar Results to Other Biologics for Severe Asthma
This systematic review and indirect treatment comparison evaluated depemokimab against omalizumab, benralizumab, dupilumab, and placebo in p…
A new review finds that the drug depemokimab performs similarly to other established biologics in reducing severe asthma flare-ups.
Higher school asthma readiness associated with 1.44 odds of asthma exacerbations in children
Better school asthma readiness linked to fewer asthma attacks in children
This observational nested cohort study of 202 children aged 5 to 13 years found that higher school asthma readiness was associated with a hi…
Children with asthma may face fewer flare-ups when their schools are better prepared with care plans and necessary medications.
Host-targeting antivirals offer a potential transformative treatment strategy for rhinovirus infection
Host Targeting Antivirals May Offer New Strategy for Common Cold
This systematic review examines host-targeting antivirals (HTAs) as an alternative to direct-acting antiviral drugs for respiratory infectio…
New research explores how host-targeting antivirals could change how we treat common cold infections and help high-risk patients.
SHVASAN model aims to improve rural screening and diagnosis of asthma and COPD
New plan aims to improve asthma and COPD screening
This study protocol describes the SHVASAN model for screening and diagnosing asthma and COPD in rural primary health care centers in India. …
A new health model aims to make it easier for rural communities to get screened and diagnosed for asthma and lung disease.
Extreme diurnal temperature range increases risk of asthma related visits in children and adolescents
Extreme temperature swings increase hospital visits for children with asthma
This meta-analysis of 14 studies examines the impact of ambient temperature variability on pediatric asthma healthcare utilization. Findings…
Rapid changes in daily temperatures are linked to more doctor visits for children with asthma, especially during the cold season.
Intravenous magnesium sulfate serves as secondary adjunctive therapy for severe refractory acute asthma exacerbations
Doctors clarify when to use magnesium for severe asthma attacks
This umbrella review synthesizes evidence regarding intravenous versus nebulized magnesium sulfate for acute asthma exacerbations. The autho…
New evidence clarifies that magnesium should only be used as a backup treatment for severe asthma cases, not as a first choice.
Fermented dairy consumption and reduced risk of asthma or wheeze in children
Fermented dairy may lower kids' asthma risk, but evidence is weak
This meta-analysis examined the relationship between fermented dairy consumption and the risk of asthma or wheeze in a large pediatric popul…
Kids who eat yogurt and similar foods may have lower odds of asthma or wheeze, but the evidence is shaky and more research is needed.
Multimodal gene prioritization improves predictive performance of polygenic transcriptome risk scores for asthma
New Genetic Framework Identifies Risk Factors for Childhood Asthma
This meta-analysis evaluates a multimodal gene prioritization framework integrating GWAS, bulk tissue eQTL, and single-cell gene eQTL data t…
A large study identifies 275 genetic locations linked to asthma, helping researchers better understand how genes influence the risk of devel…
Depemokimab maintains trough concentrations 90% above EC level with predicted half-life of 47 days
New data supports twice yearly dosing for asthma and sinus disease
This observational analysis of pharmacokinetic and pharmacodynamic data from Phase I and Phase III trials evaluated depemokimab in patients …
A new analysis of trial data shows a specific treatment for asthma and nasal polyps may only need to be given twice a year.