Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Conditions › X-linked severe combined immunodeficiency

X-linked severe combined immunodeficiency

Part of Inborn error of immunity

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
CRISPR SGE platform maps functional impact of 470 IL2RG variants in X-linked severe combined immunodeficiency
Genetics & Precision Medicine
CRISPR SGE platform maps functional impact of 470 IL2RG variants in X-linked severe combined immunodeficiency New tool maps genetic errors that break immune system cells
This article describes a CRISPR-targeted saturation genome editing (SGE) platform used to map functional impact of variants in X-linked seve…
A new method mapped 470 genetic changes in immune cells, confirming 90 that stop the cells from working properly.
medRxiv Apr 30, 2026

Research across Inborn error of immunity

Related studies from across the Inborn error of immunity family.

HSCT in AK2-Related Reticular Dysgenesis: 85.7% Survival at 10 Years
Allergy & Immunology Cohort
HSCT in AK2-Related Reticular Dysgenesis: 85.7% Survival at 10 Years Rare Immune Disorder: Early Transplant Restores Immunity in Newborns
This retrospective observational cohort study from a single high-consanguinity center evaluated 10 patients with AK2-related reticular dysge…
Early stem cell transplants may save babies with a rare immune disorder, restoring immunity and hearing stability in a small study.
Frontiers Apr 24, 2026