Research across Dementia
Related studies from across the Dementia family.
Diabetes mellitus acts as a context-dependent modifier of risk and phenotype in neurological disorders
Diabetes May Influence Risk and Progress of Neurological Disorders
This narrative review synthesizes evidence regarding the role of diabetes mellitus (DM) as a disease modifier across various neurological co…
New research suggests that diabetes can change how certain neurological conditions progress, potentially opening doors for new treatment opt…
Ligustilide shows neuroprotective effects across multiple CNS disorders in preclinical models
Ligustilide Shows Potential for Treating Various Brain Disorders
This systematic review of 55 original studies evaluates the neuroprotective potential of ligustilide (LIG) in various neurological condition…
Early research on the compound ligustilide shows potential to protect brain cells from damage caused by stroke, dementia, and other neurolog…
The osteoimmune-brain axis links systemic inflammation and bone hormones to neurodegenerative pathology
Immune system may link bone health and brain disease
This systematic review examines the role of the osteoimmune-brain axis, where the immune system mediates skeletal and cerebral pathology thr…
A new look at the body's immune system suggests a link between bone health and conditions like Alzheimer's and dementia.
Rapid advancements in imaging and blood-based biomarkers are transforming the diagnosis and management of ADRD
New guidelines help doctors tell delirium from dementia
This clinical guideline provides a narrative review on the evolving diagnostic and treatment landscape for Alzheimer's disease and related d…
Delirium is acute and fluctuating; dementia is chronic. New guidelines help doctors tell them apart.
Extended occupational therapy showed no significant improvement in behavioral symptoms for dementia patients
Extended occupational therapy shows no added benefit for dementia
This randomized controlled trial evaluated community-dwelling adults with mild-to-moderate dementia in France. Participants received occupat…
Adding four more months of occupational therapy did not improve behavioral symptoms in people with mild-to-moderate dementia, compared to st…
GLP-1 receptor agonists may reduce cognitive decline in type 2 diabetes patients with dementia
GLP-1 drugs may slow cognitive decline in type 2 diabetes
A systematic review of systematic reviews and meta-analyses found that GLP-1 receptor agonists are associated with reduced overall cognitive…
A review of reviews suggests GLP-1 drugs like Ozempic may help protect memory and thinking in people with type 2 diabetes.
SLE linked to 53% higher odds of cognitive impairment in meta-analysis of 7 million
Lupus linked to higher risk of cognitive decline
This meta-analysis of 7 observational studies involving over 7 million participants found that systemic lupus erythematosus (SLE) is signifi…
People with lupus may face 53% higher odds of cognitive impairment, a large analysis finds.
Dog-assisted therapy significantly improves behavioral symptoms in dementia patients compared to routine care in a systematic review
Dog-assisted therapy improves behavior in dementia patients
This systematic review and meta-analysis of 10 randomized controlled trials evaluated dog-assisted therapy for patients with dementia. The p…
A meta-analysis suggests dog-assisted therapy may reduce behavioral symptoms in dementia patients, though evidence remains weak due to study…
Systematic review finds inflammatory markers elevated in Alzheimer's disease compared to healthy controls across 41 studies
Inflammatory markers linked to Alzheimer's and other dementia types
This systematic review and meta-analysis examined 41 eligible studies involving healthy controls and patients with various dementia subtypes…
A large review found that people with Alzheimer's and other dementias show higher inflammation than healthy people, though more research is …
Higher EAT-Lancet diet adherence linked to lower risks of depression, anxiety, stroke, and dementia in observational cohorts
Eating healthy plant foods may lower risk of depression, anxiety, stroke, and dementia in older adults
This systematic review and meta-analysis examined associations between adherence to the EAT-Lancet diet and neuropsychiatric disorders acros…
A review of many studies found that following a plant-based diet like EAT-Lancet was linked to lower chances of depression, anxiety, stroke,…
Systematic review and meta-analysis of retinal biomarkers in frontotemporal dementia and Alzheimer disease
Retinal scans show thinner layers in frontotemporal dementia than Alzheimer disease
This systematic review and meta-analysis synthesized optical coherence tomography data on retinal biomarkers in frontotemporal dementia, Alz…
A new analysis of retinal scans found that people with frontotemporal dementia have thinner eye layers than those with Alzheimer disease or …
Depression linked to higher risk of progression from mild cognitive impairment to Alzheimer's disease and dementia in adults
Depression Linked to Higher Risk of Dementia Progression in Mild Cognitive Impairment
This systematic review and meta-analysis evaluated the association between depression and progression from mild cognitive impairment to Alzh…
A new analysis suggests depression may increase the risk of dementia progression in adults with mild cognitive impairment, though evidence c…