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Young-onset dementia

Part of Dementia

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
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Research across Dementia

Related studies from across the Dementia family.

Impact of Domain Specific Physical Activity on Risk of All Cause Dementia
Neurology Meta-analysis
Impact of Domain Specific Physical Activity on Risk of All Cause Dementia High levels of physical activity linked to lower dementia risk
A massive meta-analysis of over 4 million participants reveals that specific types of physical activity significantly influence dementia ris…
Active lifestyles, especially during leisure time, are linked to a lower risk of developing Alzheimer's and other forms of dementia.
Increased Risk of Dementia Diagnosis Among Individuals Diagnosed With Bipolar Disorder
Psychiatry Meta-analysis
Increased Risk of Dementia Diagnosis Among Individuals Diagnosed With Bipolar Disorder Bipolar disorder linked to triple dementia risk
A large-scale meta-analysis identifies a significant correlation between bipolar disorder and an elevated risk of dementia diagnosis.
People with bipolar disorder face a higher risk of dementia, a new analysis finds. The link is strong but the evidence has limits.
Dementia prevalence 24.3% in older adults with psychotic disorders, meta-analysis finds
Psychiatry Meta-analysis
Dementia prevalence 24.3% in older adults with psychotic disorders, meta-analysis finds Dementia found in 1 in 4 older adults with psychotic disorders
This meta-analysis of older adults with psychotic disorders reports a pooled dementia prevalence of 24.3% (95% CI: 20.5%-28.5%), with high h…
A new analysis finds dementia in 24.3% of older adults with psychotic disorders, highlighting the need for better care planning.
Animal-assisted interventions improve depression in dementia, but not other outcomes
Physical Medicine & Rehab Meta-analysis
Animal-assisted interventions improve depression in dementia, but not other outcomes Animal interactions may help ease depression in people with dementia
This overview of systematic reviews and meta-analyses found moderate evidence that animal-assisted interventions (AAIs) improve depression i…
Interacting with animals can significantly improve feelings of depression for people living with dementia, according to a review of recent r…
Prolonged FVEP-P2 latency is associated with Alzheimer's disease and other forms of dementia
Neurology Meta-analysis
Prolonged FVEP-P2 latency is associated with Alzheimer's disease and other forms of dementia Brain Signal Delays Linked to Alzheimer's and Dementia Types
This meta-analysis of 18 comparisons involving 1,778 participants found significantly prolonged FVEP-P2 latency in patients with Alzheimer's…
A large review found that specific brain signal delays are linked to Alzheimer's disease and other forms of cognitive decline.
Person-centered non-pharmacological interventions significantly reduce verbal agitation in patients with dementia
Neurology Meta-analysis
Person-centered non-pharmacological interventions significantly reduce verbal agitation in patients with dementia Personalized care helps reduce agitation in people with dementia
This meta-analysis of randomized controlled trials evaluates the impact of person-centered non-pharmacological interventions on agitation in…
Tailored, person-centered care can significantly lower verbal agitation in people living with dementia compared to standard methods.
SGLT2 inhibitors significantly reduce dementia risk in patients with type 2 diabetes
Diabetes & Endocrinology Meta-analysis
SGLT2 inhibitors significantly reduce dementia risk in patients with type 2 diabetes Diabetes drugs may lower dementia risk, study finds
This network meta-analysis involving 845,433 participants analyzed the impact of SGLT2 inhibitors on dementia outcomes in patients with type…
A large analysis of over 845,000 people with type 2 diabetes found that certain diabetes drugs, especially empagliflozin, were linked to a l…
Gabapentinoid use is associated with modestly higher odds of Alzheimer's disease and related dementias
Neurology Meta-analysis
Gabapentinoid use is associated with modestly higher odds of Alzheimer's disease and related dementias Reviewing the Link Between Gabapentin Use and Risk of Developing Dementia
This meta-analysis of 325,245 individuals found that gabapentinoid use was associated with modestly higher odds of Alzheimer's disease and r…
A large review looked at how gabapentin and pregabalin affect brain health. Some findings suggest a possible link to dementia.
Diabetic retinopathy is associated with a significantly higher risk of all-cause dementia
Diabetes & Endocrinology Meta-analysis
Diabetic retinopathy is associated with a significantly higher risk of all-cause dementia Diabetic retinopathy is linked to a higher risk of dementia
This meta-analysis of observational studies involving 2,887,409 patients found that diabetic retinopathy is associated with an increased ris…
A large analysis shows people with diabetic retinopathy may face an increased risk of developing dementia, highlighting the need for closer …
Elevated neutrophil-to-lymphocyte ratio correlates with greater cerebral small vessel disease burden and white matter hyperintensities
Neurology Meta-analysis
Elevated neutrophil-to-lymphocyte ratio correlates with greater cerebral small vessel disease burden and white matter hyperintensities High Neutrophil Levels Linked to Brain Small Vessel Damage
This systematic review and meta-analysis of 62,961 patients found that elevated neutrophil-to-lymphocyte ratio (NLR) is associated with the …
A large analysis finds that higher neutrophil-to-lymphocyte ratios are linked to more severe damage in the brain's small blood vessels.
Pain assessment guidelines for cognitively impaired older adults lack practical detail
Anesthesiology & Pain Medicine Sys. Review
Pain assessment guidelines for cognitively impaired older adults lack practical detail Pain guidelines for dementia patients lack practical advice
This scoping review mapped pain assessment guidelines for hospitalized older adults with cognitive impairment. No Australian guidelines were…
A review finds most pain assessment guidelines for older adults with dementia offer little practical help for hospital staff.
Network meta-analysis protocol aims to rank structured exercise interventions for fall prevention in dementia
Rheumatology Meta-analysis
Network meta-analysis protocol aims to rank structured exercise interventions for fall prevention in dementia Exercise Programs May Help Prevent Falls in Seniors with Dementia
This is a protocol for a systematic review and network meta-analysis regarding structured exercise interventions for older adults with mild …
A planned review aims to determine which types of structured exercise best help older adults with memory loss stay safe and avoid falling.