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Home › Medications › adalimumab

adalimumab

14 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of adalimumab

132 trials tracked of adalimumab: 102 in phase 3 or 4 and 49 with published results. The most-cited published study has 930 citations.

132Trials tracked
102Phase 3 & 4
0Recruiting
49With published results
Phase distribution
Phase 4 23 Phase 3 79 Phase 2 19 Phase 1 1 Other / NA 10
  1. Phase 3 Efficacy and Safety of Two Treatment Algorithms in Adults With Moderate to Severe Crohn's Disease Completed · 930 cited
  2. Phase 3 An Efficacy and Safety Study of Vedolizumab Intravenous (IV) Compared to Adalimumab Subcutaneous (SC) in Participants With Ulcerative Colitis Completed · 737 cited
  3. Phase 3 Efficacy and Safety of Adalimumab in Patients With Active Uveitis Completed · 669 cited
  4. Phase 3 Efficacy and Safety of Adalimumab in Subjects With Inactive Uveitis Completed · 522 cited
  5. Phase 3 BI 655066/ABBV-066 (Risankizumab) Compared to Active Comparator (Adalimumab) in Patients With Moderate to Severe Chronic Plaque Psoriasis Completed · 302 cited
  6. Phase 3 Efficacy of Secukinumab Compared to Adalimumab in Patients With Psoriatic Arthritis Completed · 285 cited
Show 44 more trials
  1. Phase 3 Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis Completed · 188 cited
  2. Phase 3 A Study in Moderate to Severe Rheumatoid Arthritis Completed · 168 cited
  3. Phase 4 Safety and Efficacy of Adalimumab (Humira) for Hidradenitis Suppurativa (HS) Peri-Surgically Completed · 162 cited
  4. Phase 3 A Double Blind Study in Pediatric Subjects With Chronic Plaque Psoriasis, Studying Adalimumab vs. Methotrexate Completed · 153 cited
  5. Phase 4 Vascular Inflammation in Psoriasis - Extension Study Completed · 149 cited
  6. Phase 3 A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis Completed · 112 cited
  7. Phase 3 Continuing Versus Withdrawing Adalimumab in Maintaining Remission in Non-Radiographic Axial Spondyloarthritis Completed · 102 cited
  8. Phase 4 Triple Combination Therapy in High Risk Crohn's Disease (CD) Completed · 93 cited
  9. Phase 3 A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors Completed · 92 cited
  10. Phase 3 A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors Completed · 92 cited
  11. Phase 3 Study of Adalimumab in Participants With Peripheral Spondyloarthritis (SpA) Completed · 87 cited
  12. Phase 3 Study to Evaluate Efficacy and Safety of Two Drug Regimens in Subjects With Moderate to Severe Crohn's Disease Completed · 86 cited
  13. Phase 3 A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis With Randomized Withdrawal and Retreatment Completed · 84 cited
  14. Phase 3 Study to Compare Efficacy and Safety of ABP 501 and Adalimumab (HUMIRA®) in Adults With Moderate to Severe Plaque Psoriasis Completed · 82 cited
  15. Phase 3 Efficacy and Safety of Adalimumab in Pediatric Subjects With Moderate to Severe Ulcerative Colitis Completed · 82 cited
  16. Phase 4 Treatments Against RA and Effect on FDG-PET/CT Completed · 77 cited
  17. Phase 3 A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis Completed · 66 cited
  18. Phase 3 Efficacy and Long Term Safety of Adalimumab in Pediatric Subjects Who Have Demonstrated Clinical Response in M06-806 Completed · 62 cited
  19. Phase 3 A Study of the Long-term Safety and Efficacy of Adalimumab in Subjects With Intermediate-, Posterior-, or Pan-uveitis Completed · 61 cited
  20. Phase 3 A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis Completed · 58 cited
  21. Phase 3 A Study Of PF-06410293 (Adalimumab-Pfizer) And Adalimumab (Humira®) In Combination With Methotrexate In Subjects With Active Rheumatoid Arthritis (REFLECTIONS B538-02). Completed · 56 cited
  22. Phase 3 Study to Evaluate the Safety and Efficacy of Adalimumab in Chinese Subjects With Moderate to Severe Crohn's Disease Completed · 55 cited
  23. Phase 4 Study to Assess Changes in the Immune Profile in Adults With Early Rheumatoid Arthritis Completed · 53 cited
  24. Phase 3 A Study to Test the Efficacy and Safety of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis Completed · 48 cited
  25. Phase 4 A Study of Ixekizumab (LY2439821) Versus Adalimumab in Participants With Psoriatic Arthritis Completed · 46 cited
  26. Phase 3 A Study to Evaluate the Impact of Adalimumab on Quality of Life, Health Care Utilization and Costs of Ulcerative Colitis Subjects in the Usual Clinical Practice Setting Completed · 44 cited
  27. Phase 4 A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) Subjects Completed · 40 cited
  28. Phase 3 Long-term Open-label Safety and Efficacy Study of Adalimumab in Subjects With Ulcerative Colitis Completed · 33 cited
  29. Phase 3 Study to Demonstrate Non-Inferior Efficacy and Safety of CinnoRA® Versus Humira® for Treatment of Active RA Completed · 33 cited
  30. Phase 3 A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (DMARD) Completed · 31 cited
  31. Phase 3 Efficacy and Safety of Sarilumab and Adalimumab Monotherapy in Patients With Rheumatoid Arthritis (SARIL-RA-MONARCH) Completed · 25 cited
  32. Phase 4 Adalimumab in JIA-associated Uveitis Stopping Trial Completed · 24 cited
  33. Phase 3 Study to Evaluate the Safety and Efficacy of Two Adalimumab Dosing Regimens in Subjects With Moderate to Severe Ulcerative Colitis Completed · 20 cited
  34. Phase 4 Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis Completed · 19 cited
  35. Phase 3 A Comparative Study Between PF-06410293 and Humira® in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis Completed · 15 cited
  36. Phase 4 Evaluation of the Optimal MTX Dose as an Add-on Therapy to Adalimumab for RA Patients in Japan, South Korea and Taiwan Completed · 14 cited
  37. Phase 3 A Study of Adalimumab After Dose Escalation in Japanese Subjects With Crohn's Disease Completed · 13 cited
  38. Phase 3 Filgotinib in Combination With Methotrexate in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Completed · 12 cited
  39. Phase 3 A Study of Ixekizumab (LY2439821) in bDMARD-Naive Participants With Radiographic Axial Spondyloarthritis Completed · 8 cited
  40. Phase 3 A Study of Ixekizumab in Participants With Active Psoriatic Arthritis Completed · 8 cited
  41. Phase 4 Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial Completed · 4 cited
  42. Phase 3 Efficacy And Safety Of Tofacitinib In Psoriatic Arthritis: Comparator Study Completed · 2 cited
  43. Phase 3 A Comparative Study Between ABP 501 and Humira® in Participants With Moderate to Severe Plaque Psoriasis Completed · 1 cited
  44. Phase 4 A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid Arthritis Completed

Showing the 50 most-cited and recently-updated of 132 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Sudden sensorineural hearing loss risk factors in ankylosing spondylitis patients on adalimumab plus methotrexate
Neurology Cohort
Sudden sensorineural hearing loss risk factors in ankylosing spondylitis patients on adalimumab plus methotrexate Could long-term arthritis treatment raise your risk of sudden hearing loss?
This retrospective case-control analysis drew on 2,564 ankylosing spondylitis patients at Henan Provincial People's Hospital (2015-2024), co…
Patients with long-term ankylosing spondylitis taking adalimumab and methotrexate are more likely to experience sudden hearing loss than tho…
Frontiers Apr 16, 2026
Vedolizumab with Adalimumab or Ustekinumab Studied for Crohn's Endoscopic Response
Gastroenterology Phase IV
Vedolizumab with Adalimumab or Ustekinumab Studied for Crohn's Endoscopic Response Can New Drug Combinations Offer Hope for Crohn's Disease Sufferers?
Phase 4 trial investigates vedolizumab with adalimumab or ustekinumab in Crohn's. Primary endpoint: endoscopic response at 26 weeks.
Adults with moderate to severe Crohn's disease may find new relief by combining vedolizumab with adalimumab or ustekinumab before continuing…
CT.gov Mar 27, 2026