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Patient Mode — summaries use plain language, avoiding clinical jargon.
Drug Pipeline
RCT
Baricitinib showed limited efficacy in pediatric JIA-uveitis patients refractory to methotrexate or biologics at week 24.
New Hope for Kids with Stubborn Eye Inflammation
This open-label, active-controlled phase-3 multicenter trial enrolled 30 pediatric patients with juvenile idiopathic arthritis-associated uv…
A new drug shows early promise for children with stubborn eye inflammation who didn't respond to standard treatments, offering hope when oth…
Apr 18, 2026
Drug Pipeline
RCT
Baricitinib maintains SALT score ≤20 in adults with severe alopecia areata over 152 weeks.
Baricitinib maintained hair regrowth in severe alopecia areata for over three years in this trial.
This phase 3 RCT evaluated continuous baricitinib in 196 adults with severe alopecia areata. At 152 weeks, 89.1% on 4 mg and 83.6% on 2 mg m…
Baricitinib kept hair growing on the scalp, eyebrows, and eyelashes for over three years in adults with severe alopecia areata who responded…
Apr 18, 2026
Psychiatry
Cohort
Hospitalized AE-RA-ILD patients receiving JAK inhibitors alongside glucocorticoids showed mixed respiratory outcomes over three months.
A Rheumatoid Arthritis Drug May Help Save Lungs in Crisis
This retrospective observational case series examined six consecutive patients hospitalized for acute exacerbation of rheumatoid arthritis–a…
A small study suggests a familiar arthritis pill may help calm sudden, dangerous lung flare-ups in people with rheumatoid arthritis.
Frontiers
Apr 16, 2026
Dermatology
Meta-analysis
Meta-analysis finds oral JAK inhibitors increase HDL and LDL cholesterol levels in patients from RCTs
Common arthritis and skin drugs linked to cholesterol changes, analysis finds
A systematic review and meta-analysis of 13 phase 2 and 3 RCTs involving 5,658 patients found treatment with oral JAK inhibitors (baricitini…
Common arthritis and skin drugs can raise both 'good' and 'bad' cholesterol levels, a review of nearly 4,000 patients shows.
Apr 4, 2026