VerifyNow-guided antiplatelet modification linked to lower stroke recurrence in atherothrombotic or lacunar infarction
Testing Blood Saves Stroke Patients From Recurrence
A retrospective observational study of 243 patients with atherothrombotic or lacunar infarction found that VerifyNow-guided antiplatelet the…
Doctors who adjusted blood thinner choices based on a simple blood test saw far fewer repeat strokes in patients with prior clots.
Infliximab in IVIG-resistant Kawasaki disease with cholestatic hepatitis: case report
Can a new drug stop heart damage in Kawasaki disease when standard treatments fail?
A case report describes a 2-year-old Han Chinese male with IVIG-resistant Kawasaki disease and cholestatic hepatitis treated with infliximab…
In a two-year-old boy with Kawasaki disease, the drug infliximab quickly stopped his fever and liver trouble, yet his heart artery damage ke…
Cerebral infarction common in tuberculous meningitis and linked to disease severity and arterial occlusion
Could blood thinners or specific treatments make brain strokes worse in severe meningitis?
This secondary analysis of the ACT-TBM randomized trial examined 226 patients with tuberculous meningitis at two tertiary centers in India. …
Patients with tuberculous meningitis and blocked arteries were much more likely to develop strokes, especially if they received modified tub…
Ten-year HOST-EXAM trial data show clopidogrel reduces major adverse events versus aspirin in chronic PCI maintenance.
Long-term clopidogrel may lower risks compared to aspirin after heart stents
This 10-year extended follow-up of the HOST-EXAM randomized controlled trial evaluated clopidogrel versus aspirin in 5,438 patients during t…
After heart stents, long-term clopidogrel alone lowered risks of major heart events and death compared to aspirin alone in a 10-year study.
Adding low-dose rivaroxaban to DAPT did not significantly reduce LV thrombus in anterior STEMI patients.
Adding low-dose rivaroxaban to standard heart attack drugs did not clearly prevent blood clots in the heart
This randomized clinical trial evaluated 560 patients with anterior ST-segment elevation myocardial infarction (STEMI) across 29 centers in …
Adding a low-dose blood thinner to standard heart attack drugs did not clearly prevent dangerous clots in the heart, based on a trial of 560…
Regular antithrombotic use associated with increased nonbiliary pancreatitis risk in UK Biobank cohort
Large UK study finds link between blood-thinning drugs and pancreatitis risk
A prospective cohort study of 431,754 UK Biobank participants found regular antithrombotic drug use was associated with a 31% increased risk…
Regular blood-thinning drug use is linked to a 31% higher risk of a specific pancreatitis type, with clopidogrel showing the strongest conne…
Lp-PLA2 activity does not significantly modify dual antiplatelet therapy efficacy in minor stroke/TIA with CYP2C19 loss-of-function alleles
Blood enzyme levels don't change which stroke prevention drug works better, study finds
This subgroup analysis of the CHANCE-2 RCT examined 5919 patients with minor stroke/TIA and CYP2C19 loss-of-function alleles. Lp-PLA2 activi…
A simple blood test for inflammation doesn't predict which stroke prevention drug works best for patients with a specific genetic trait.
Protocol for argatroban plus clopidogrel versus aspirin plus clopidogrel in acute minor ischemic stroke
Study will compare two blood thinner combinations for minor strokes
This is a study protocol for a randomized controlled trial of 464 patients with acute minor ischemic stroke (NIHSS ≤5) within 72 hours. It w…
A new trial will test if adding argatroban to clopidogrel leads to better recovery than aspirin plus clopidogrel for minor stroke patients.
Post hoc analysis finds cilostazol reduces stroke recurrence without lowering systolic blood pressure
Study finds cilostazol reduces stroke recurrence without lowering blood pressure
A post hoc mediation analysis of an RCT in 1,795 patients with noncardioembolic ischemic stroke found dual therapy with cilostazol plus aspi…
Cilostazol lowers stroke recurrence risk in patients with prior noncardioembolic strokes without working by dropping their blood pressure.