Obstructive sleep apnea is associated with a 2- to 3-fold increase in stroke risk
Sleep disorders significantly impact recovery for stroke patients
This narrative review examines the prevalence and impact of sleep disorders, including obstructive sleep apnea (OSA), in stroke patients. Th…
Up to 84% of stroke patients suffer from sleep disorders, which can hinder recovery and increase the risk of future strokes.
Phenotype-guided pharmacologic management of postoperative sleep disturbance in breast cancer patients may improve outcomes
Tailored Medication Options for Sleep Issues After Breast Surgery
This narrative review explores the pharmacological management of postoperative sleep disturbance (PSD) in breast cancer patients following s…
Newer strategies suggest matching specific medications to the type of sleep issues patients face after breast cancer surgery.
Circadian rhythm disruption is a core pathophysiological mechanism for anxiety and depressive disorders
Circadian Disruption Linked to Anxiety and Depression
This systematic review examines the role of circadian rhythms in mental health. It identifies circadian disruption as a primary pathophysiol…
A new review suggests fixing your body clock could be key to treating anxiety and depression, not just a side effect.
Multimodal pharmacological and behavioral strategies may improve perioperative sleep management in cardiac surgery patients
New ways to manage sleep for heart surgery patients
This evidence-oriented narrative review synthesizes the efficacy of melatonin, dexmedetomidine, GABAergic hypnotics, and respiratory support…
Managing sleep after heart surgery is complex. New research looks at how different medications and oxygen tools can help patients rest bette…
Erratum issued for previous report on pediatric melatonin ingestions in the US
Correction issued for earlier report on children swallowing melatonin
An erratum has been published for a prior report on pediatric melatonin ingestions in the United States. No study details, results, or corre…
A journal correction warns that a report on children swallowing melatonin contains an error, leaving the public without clear facts until de…
Review of preclinical interventions for heat stroke pathophysiology and gaps
Heat Stroke Harms Your Cells: New Clues Could Change Treatment
This narrative review synthesizes preclinical evidence on several compounds for heat stroke pathophysiology. The authors note mitochondrial …
Heat stroke doesn't just raise your temperature, it shuts down your cells' power plants, and new research points to ways of protecting them …
Network meta-analysis of pediatric atopic dermatitis treatments shows dupilumab and pimecrolimus efficacy
Dupilumab and Pimecrolimus Lead New Rankings for Children's Eczema Relief
This network meta-analysis evaluated dupilumab, pimecrolimus, melatonin, probiotics, tralokinumab, nemolizumab, and vitamin D for pediatric …
A new analysis ranks the top treatments for children's eczema, with dupilumab and pimecrolimus leading for symptom relief.
Sleep efficiency improved with mindfulness in multiple sclerosis patients according to a meta-analysis
Mindfulness and Melatonin May Help Sleep in Multiple Sclerosis
This systematic review and meta-analysis evaluated non-pharmacologic and pharmacologic interventions for sleep in people with multiple scler…
A review of ten studies suggests mindfulness, melatonin, and other therapies may improve sleep for people with multiple sclerosis, though mo…
Narrative review proposes redox-guided framework for vitamin D, myo-inositol, and melatonin in PCOS
Researchers propose new PCOS framework using vitamin D and melatonin
This narrative review synthesizes existing data on combined vitamin D, myo-inositol, and melatonin supplementation for polycystic ovary synd…
A new framework suggests combining vitamin D, myo-inositol, and melatonin for PCOS ovulation and insulin markers.
Narrative review suggests melatonin for ICU sleep only after non-pharmacologic measures fail
New Sleep Strategies Could Help ICU Patients Heal Sooner
This narrative review addresses the pharmacologic management of sleep in ICU patients.
ICU patients sleep poorly due to stress. New research shows better sleep strategies could help them heal faster without risky drugs.
Narrative review associates melatonin use with delayed age-related macular degeneration in Americans over 40
Melatonin May Slow Vision Loss in Aging Eyes
This narrative review examines the association between melatonin use and delayed age-related macular degeneration (AMD) in Americans over th…
Melatonin, the sleep hormone, may slow vision loss in aging eyes by fighting the oxidative stress that damages cells in age-related macular …
Melatonin treatment in term or late preterm newborns with neonatal encephalopathy shows very uncertain effects on mortality or disability
Could Melatonin Protect Newborn Brains? We Still Don't Know
This systematic review and meta-analysis evaluated melatonin in newborns with neonatal encephalopathy.
Melatonin shows promise in animal studies for protecting newborn brains from oxygen injury, but human trials are too few to guide treatment …
All melatonin Articles
- Obstructive sleep apnea is associated with a 2- to 3-fold increase in stroke risk
- Phenotype-guided pharmacologic management of postoperative sleep disturbance in breast cancer patients may improve outcomes
- Circadian rhythm disruption is a core pathophysiological mechanism for anxiety and depressive disorders
- Multimodal pharmacological and behavioral strategies may improve perioperative sleep management in cardiac surgery patients
- Erratum issued for previous report on pediatric melatonin ingestions in the US
- Review of preclinical interventions for heat stroke pathophysiology and gaps
- Network meta-analysis of pediatric atopic dermatitis treatments shows dupilumab and pimecrolimus efficacy
- Sleep efficiency improved with mindfulness in multiple sclerosis patients according to a meta-analysis
- Narrative review proposes redox-guided framework for vitamin D, myo-inositol, and melatonin in PCOS
- Narrative review suggests melatonin for ICU sleep only after non-pharmacologic measures fail
- Narrative review associates melatonin use with delayed age-related macular degeneration in Americans over 40
- Melatonin treatment in term or late preterm newborns with neonatal encephalopathy shows very uncertain effects on mortality or disability
- Oral melatonin adjunct therapy improves echocardiographic parameters and clinical outcomes in neonates with persistent pulmonary hypertension of the newborn
- Emergency department visits for unsupervised melatonin ingestion in infants and young children reported
- High-dose melatonin linked to hepatotoxicity in small PP-MS trial, prompting early halt