HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Neurology
Meta-analysis
Sleep efficiency improved with mindfulness in multiple sclerosis patients according to a meta-analysis
Mindfulness and Melatonin May Help Sleep in Multiple Sclerosis
This systematic review and meta-analysis evaluated non-pharmacologic and pharmacologic interventions for sleep in people with multiple scler…
A review of ten studies suggests mindfulness, melatonin, and other therapies may improve sleep for people with multiple sclerosis, though mo…
May 1, 2026
Diabetes & Endocrinology
Sys. Review
Narrative review proposes redox-guided framework for vitamin D, myo-inositol, and melatonin in PCOS
Researchers propose new PCOS framework using vitamin D and melatonin
This narrative review synthesizes existing data on combined vitamin D, myo-inositol, and melatonin supplementation for polycystic ovary synd…
A new framework suggests combining vitamin D, myo-inositol, and melatonin for PCOS ovulation and insulin markers.
Frontiers
Apr 28, 2026
Neurology
Sys. Review
Narrative review suggests melatonin for ICU sleep only after non-pharmacologic measures fail.
New Sleep Strategies Could Help ICU Patients Heal Sooner
This narrative review addresses the pharmacologic management of sleep in ICU patients. The authors note that melatonin and melatonin recepto…
ICU patients sleep poorly due to stress. New research shows better sleep strategies could help them heal faster without risky drugs.
Frontiers
Apr 28, 2026
Ophthalmology
Sys. Review
Narrative review associates melatonin use with delayed age-related macular degeneration in Americans over 40
Melatonin May Slow Vision Loss in Aging Eyes
This narrative review examines the association between melatonin use and delayed age-related macular degeneration (AMD) in Americans over th…
Melatonin, the sleep hormone, may slow vision loss in aging eyes by fighting the oxidative stress that damages cells in age-related macular …
Frontiers
Apr 15, 2026
Pediatrics
Meta-analysis
Melatonin treatment in term or late preterm newborns with neonatal encephalopathy shows very uncertain effects on mortality or disability.
Could Melatonin Protect Newborn Brains? We Still Don't Know
This systematic review and meta-analysis evaluated melatonin in newborns with neonatal encephalopathy. Based on one pilot study, evidence re…
Melatonin shows promise in animal studies for protecting newborn brains from oxygen injury, but human trials are too few to guide treatment …
Apr 14, 2026
Pediatrics
RCT
Oral melatonin adjunct therapy improves echocardiographic parameters and clinical outcomes in neonates with persistent pulmonary hypertension of the newborn.
Could The Sleep Hormone Help Newborn Hearts Heal Faster?
This randomized controlled trial evaluated oral melatonin added to standard therapy versus standard therapy alone in 80 neonates with persis…
Adding melatonin to standard care helped newborn hearts pump stronger and got babies off ventilators sooner in a careful 80-baby trial.
Apr 13, 2026
Neurology
RCT
High-dose melatonin linked to hepatotoxicity in small PP-MS trial, prompting early halt
High-dose melatonin trial halted after liver safety concerns in MS patients
A phase I/II RCT of 8 patients with PP-MS on stable ocrelizumab found that adjunctive high-dose oral melatonin (300 mg/day) was associated w…
A high-dose melatonin trial for multiple sclerosis stopped early after three of four patients developed mild liver injury, though the issue …
Apr 4, 2026
Pediatrics
Erratum issued for previous report on pediatric melatonin ingestions in the US
Correction issued for earlier report on children swallowing melatonin
An erratum has been published for a prior report on pediatric melatonin ingestions in the United States. No study details, results, or corre…
A journal correction warns that a report on children swallowing melatonin contains an error, leaving the public without clear facts until de…
CDC
Apr 4, 2026
Pediatrics
Emergency department visits for unsupervised melatonin ingestion in infants and young children reported.
Are more young children ending up in emergency rooms after eating melatonin?
An observational report describes emergency department visits in the US for unsupervised melatonin ingestion among infants and young childre…
A new report tracks emergency room visits for infants and young children who ate melatonin without supervision.
CDC
Apr 4, 2026