HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Rheumatology
RCT
Short-term prednisolone bridging enables 95% discontinuation in new rheumatoid arthritis patients after 24 months
Most patients stop steroid use after a short bridge to methotrexate treatment
This randomized controlled trial enrolled 230 patients with newly diagnosed rheumatoid arthritis naive to disease-modifying antirheumatic dr…
A trial of 230 patients with new rheumatoid arthritis found that most could stop using prednisolone after just seven weeks of short-term bri…
Jun 5, 2026
Ophthalmology
Meta-analysis
Network meta-analysis compares adjunctive therapies for proliferative vitreoretinopathy
Oral retinoic acid shows promise for retinal detachment repair
Oral retinoic acid significantly improves retinal reattachment rates in PVR patients, with strong evidence for visual acuity and reduced com…
A study found oral retinoic acid may improve retinal reattachment rates after surgery for certain eye conditions, offering a potential new t…
Jun 1, 2026
Pediatrics
RCT
Mycophenolate mofetil non-inferior to prednisone for first-episode nephrotic syndrome in children
Mycophenolate Mofetil Offers Alternative to Steroids for Nephrotic Syndrome
This phase 3 non-inferiority trial randomized 272 children aged 1-10 years with first-episode steroid-sensitive nephrotic syndrome to mycoph…
A new trial shows mycophenolate mofetil works as well as prednisone for children with nephrotic syndrome, with fewer steroid side effects.
May 1, 2026
Neurology
Cohort
Obesity associated with reduced SLE relapse rates in Japanese registry cohort
A Surprising Link Between Weight and Lupus Flares
This observational cohort study of 1134 patients with systemic lupus erythematosus in Japan found that obesity (BMI ≥25 kg/m2) was associate…
Being overweight or mildly obese might lower the risk of lupus relapses, challenging common beliefs about weight and autoimmune disease.
Frontiers
Apr 19, 2026
Drug Pipeline
RCT
Dazdotuftide inferior to prednisolone for uveitis inflammation but superior IOP safety in phase 3 trial
New Eye Drops Control Inflammation Without the Glaucoma Risk
In a randomized, double-masked, multicenter phase 3 trial of 136 adult and pediatric patients with active anterior noninfectious uveitis, to…
This new treatment offers a safer way to calm eye inflammation without raising the pressure that can lead to blindness.
Apr 17, 2026
Cardiology
RCT
Prednisolone plus standard treatment did not significantly reduce coronary-artery lesions in newly diagnosed Kawasaki disease patients
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients
This multicenter, open-label, randomized, controlled trial evaluated 3208 participants with newly diagnosed Kawasaki disease in China.
Adding prednisolone to standard care did not prevent heart damage in Kawasaki disease patients, as lesion rates remained nearly the same.
Apr 16, 2026